megakaryocyte Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A large cell that has a lobulated nucleus, is found especially in the bone marrow, and is the source of blood platelets. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000843)
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Genes

65 genes co-occuring with the biological term megakaryocyte in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
CD40LG CD40 ligand
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DNM3 dynamin 3
E2F6 E2F transcription factor 6
EGR1 early growth response 1
F13A1 coagulation factor XIII, A1 polypeptide
F5 coagulation factor V (proaccelerin, labile factor)
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FN1 fibronectin 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GFI1B growth factor independent 1B transcription repressor
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP6 glycoprotein VI (platelet)
HOXA1 homeobox A1
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL20 interleukin 20
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KLF1 Kruppel-like factor 1 (erythroid)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LYN LYN proto-oncogene, Src family tyrosine kinase
MECOM MDS1 and EVI1 complex locus
MIR105-1 microRNA 105-1
MIR105-2 microRNA 105-2
MIR10A microRNA 10a
MIR28 microRNA 28
MPL MPL proto-oncogene, thrombopoietin receptor
MSLN mesothelin
MSLNL mesothelin-like
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2 nuclear factor, erythroid 2
NUDC nudC nuclear distribution protein
ORAI1 ORAI calcium release-activated calcium modulator 1
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
PLAU plasminogen activator, urokinase
PRG4 proteoglycan 4
PRKCE protein kinase C, epsilon
PRNP prion protein
RUNX1 runt-related transcription factor 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SPP1 secreted phosphoprotein 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
STIM1 stromal interaction molecule 1
STMN1 stathmin 1
TAL1 T-cell acute lymphocytic leukemia 1
THPO thrombopoietin
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VIP vasoactive intestinal peptide
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VIPR1 vasoactive intestinal peptide receptor 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)