| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the megestrol-3091 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ABHD6 | abhydrolase domain containing 6 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACVR1B | activin A receptor, type IB |
| ADORA3 | adenosine A3 receptor |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| BIN1 | bridging integrator 1 |
| CABP2 | calcium binding protein 2 |
| CBR3 | carbonyl reductase 3 |
| CBX7 | chromobox homolog 7 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CENPO | centromere protein O |
| CHN2 | chimerin 2 |
| DICER1 | dicer 1, ribonuclease type III |
| DPEP2 | dipeptidase 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERICH1 | glutamate-rich 1 |
| EXO5 | exonuclease 5 |
| FAM120C | family with sequence similarity 120C |
| FAM174B | family with sequence similarity 174, member B |
| FPR1 | formyl peptide receptor 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| G6PC3 | glucose 6 phosphatase, catalytic, 3 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GNLY | granulysin |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTPBP1 | GTP binding protein 1 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HOXC8 | homeobox C8 |
| HOXD10 | homeobox D10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFT140 | intraflagellar transport 140 |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL1R1 | interleukin 1 receptor, type I |
| IL1R2 | interleukin 1 receptor, type II |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIF1C | kinesin family member 1C |
| KLK2 | kallikrein-related peptidase 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LTA | lymphotoxin alpha |
| MAGIX | MAGI family member, X-linked |
| MED16 | mediator complex subunit 16 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MRC2 | mannose receptor, C type 2 |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MYO6 | myosin VI |
| NLGN1 | neuroligin 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OBSL1 | obscurin-like 1 |
| OLFML2A | olfactomedin-like 2A |
| PCDH11Y | protocadherin 11 Y-linked |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PGAP1 | post-GPI attachment to proteins 1 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PQLC2 | PQ loop repeat containing 2 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASAL2 | RAS protein activator like 2 |
| RBPMS | RNA binding protein with multiple splicing |
| RELN | reelin |
| RGS12 | regulator of G-protein signaling 12 |
| RPLP2 | ribosomal protein, large, P2 |
| SDC2 | syndecan 2 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC35F5 | solute carrier family 35, member F5 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPAG8 | sperm associated antigen 8 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| SV2A | synaptic vesicle glycoprotein 2A |
| TAOK2 | TAO kinase 2 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TMEM63A | transmembrane protein 63A |
| TNC | tenascin C |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TRAF4 | TNF receptor-associated factor 4 |
| WDR25 | WD repeat domain 25 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF219 | zinc finger protein 219 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACPP | acid phosphatase, prostate |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ARG1 | arginase 1 |
| BEND5 | BEN domain containing 5 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC85C | coiled-coil domain containing 85C |
| CDHR2 | cadherin-related family member 2 |
| CDO1 | cysteine dioxygenase type 1 |
| CELP | carboxyl ester lipase pseudogene |
| CEP170B | centrosomal protein 170B |
| CES3 | carboxylesterase 3 |
| CHPF | chondroitin polymerizing factor |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLCA1 | chloride channel accessory 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL9A2 | collagen, type IX, alpha 2 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CPNE7 | copine VII |
| CPTP | ceramide-1-phosphate transfer protein |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| EXOSC1 | exosome component 1 |
| FAM212B | family with sequence similarity 212, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FRMD1 | FERM domain containing 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GALK1 | galactokinase 1 |
| GPR35 | G protein-coupled receptor 35 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| IL22 | interleukin 22 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLK5 | kallikrein-related peptidase 5 |
| KRTAP2-4 | keratin associated protein 2-4 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LBH | limb bud and heart development |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOXL3 | lysyl oxidase-like 3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MED31 | mediator complex subunit 31 |
| MEFV | Mediterranean fever |
| MX1 | MX dynamin-like GTPase 1 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NES | nestin |
| NMB | neuromedin B |
| NNAT | neuronatin |
| NOL10 | nucleolar protein 10 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PLCD1 | phospholipase C, delta 1 |
| PLCL1 | phospholipase C-like 1 |
| PLD3 | phospholipase D family, member 3 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PSKH1 | protein serine kinase H1 |
| RANBP17 | RAN binding protein 17 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RND1 | Rho family GTPase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC2A4 | solute carrier family 2 (facilitated glucose transporter), member 4 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| ST7L | suppression of tumorigenicity 7 like |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STATH | statherin |
| STX11 | syntaxin 11 |
| TAS2R4 | taste receptor, type 2, member 4 |
| TMEM212 | transmembrane protein 212 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZNF132 | zinc finger protein 132 |
| ZNF528 | zinc finger protein 528 |
| ZNF549 | zinc finger protein 549 |
| ZNF695 | zinc finger protein 695 |
| ZNF74 | zinc finger protein 74 |
