| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the megestrol-5013 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| BLVRA | biliverdin reductase A |
| CALCR | calcitonin receptor |
| CD52 | CD52 molecule |
| CDC14B | cell division cycle 14B |
| CLDN1 | claudin 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| DAPK2 | death-associated protein kinase 2 |
| DOCK5 | dedicator of cytokinesis 5 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECE1 | endothelin converting enzyme 1 |
| EFNB3 | ephrin-B3 |
| EGR3 | early growth response 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| ETV5 | ets variant 5 |
| FAM46C | family with sequence similarity 46, member C |
| FGF18 | fibroblast growth factor 18 |
| FLJ11292 | |
| FSCN1 | fascin actin-bundling protein 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GK | glycerol kinase |
| GLRA2 | glycine receptor, alpha 2 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| H2AFX | H2A histone family, member X |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HR | hair growth associated |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL27RA | interleukin 27 receptor, alpha |
| IL6ST | interleukin 6 signal transducer |
| ING1 | inhibitor of growth family, member 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JAK2 | Janus kinase 2 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIF5C | kinesin family member 5C |
| KLF6 | Kruppel-like factor 6 |
| KLHL25 | kelch-like family member 25 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LENEP | lens epithelial protein |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOC644450 | uncharacterized LOC644450 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MLXIP | MLX interacting protein |
| MMP3 | matrix metallopeptidase 3 |
| MST1 | macrophage stimulating 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OSBPL10 | oxysterol binding protein-like 10 |
| OVOL1 | ovo-like zinc finger 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTHLH | parathyroid hormone-like hormone |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PVR | poliovirus receptor |
| RB1 | retinoblastoma 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RPL7 | ribosomal protein L7 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RUNX1 | runt-related transcription factor 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SGCE | sarcoglycan, epsilon |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMAD6 | SMAD family member 6 |
| SRCAP | Snf2-related CREBBP activator protein |
| STEAP4 | STEAP family member 4 |
| SYBU | syntabulin (syntaxin-interacting) |
| TEF | thyrotrophic embryonic factor |
| THBS1 | thrombospondin 1 |
| TMEM63A | transmembrane protein 63A |
| TP63 | tumor protein p63 |
| TRAIP | TRAF interacting protein |
| TSPAN9 | tetraspanin 9 |
| VNN2 | vanin 2 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF589 | zinc finger protein 589 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A4GALT | alpha 1,4-galactosyltransferase |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALPK1 | alpha-kinase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARRB1 | arrestin, beta 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BLNK | B-cell linker |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFAP44 | cilia and flagella associated protein 44 |
| CLSTN2 | calsyntenin 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CUL9 | cullin 9 |
| DEAF1 | DEAF1 transcription factor |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EFNA3 | ephrin-A3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| F2R | coagulation factor II (thrombin) receptor |
| FAM50B | family with sequence similarity 50, member B |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GLI3 | GLI family zinc finger 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| JMJD4 | jumonji domain containing 4 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIF13B | kinesin family member 13B |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MSI1 | musashi RNA-binding protein 1 |
| N4BP3 | NEDD4 binding protein 3 |
| NME5 | NME/NM23 family member 5 |
| NRSN2 | neurensin 2 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PER3 | period circadian clock 3 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKX | protein kinase, X-linked |
| PTK6 | protein tyrosine kinase 6 |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF122 | ring finger protein 122 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A9 | S100 calcium binding protein A9 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SH2D4A | SH2 domain containing 4A |
| SIX1 | SIX homeobox 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TCTN1 | tectonic family member 1 |
| TEX40 | testis expressed 40 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMC5 | transmembrane channel-like 5 |
| TMEM242 | transmembrane protein 242 |
| TMEM254 | transmembrane protein 254 |
| TNS3 | tensin 3 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM21 | tripartite motif containing 21 |
| TRIM66 | tripartite motif containing 66 |
| TSGA10 | testis specific, 10 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| WLS | wntless Wnt ligand secretion mediator |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF205 | zinc finger protein 205 |
| ZNF639 | zinc finger protein 639 |
| ZNF696 | zinc finger protein 696 |
| ZNF862 | zinc finger protein 862 |
