| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the megestrol-6468 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE | angiotensin I converting enzyme |
| ACVRL1 | activin A receptor type II-like 1 |
| AGER | advanced glycosylation end product-specific receptor |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
| ARL4D | ADP-ribosylation factor-like 4D |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| C5AR1 | complement component 5a receptor 1 |
| CADM4 | cell adhesion molecule 4 |
| CAMKV | CaM kinase-like vesicle-associated |
| CIB2 | calcium and integrin binding family member 2 |
| CLEC10A | C-type lectin domain family 10, member A |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CREB5 | cAMP responsive element binding protein 5 |
| CRYAB | crystallin, alpha B |
| DAPK1 | death-associated protein kinase 1 |
| DLX2 | distal-less homeobox 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| EGR3 | early growth response 3 |
| EMID1 | EMI domain containing 1 |
| ENG | endoglin |
| EPHB2 | EPH receptor B2 |
| EPYC | epiphycan |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FHL1 | four and a half LIM domains 1 |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
| FLJ22184 | |
| FOLR1 | folate receptor 1 (adult) |
| FOSL2 | FOS-like antigen 2 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GFAP | glial fibrillary acidic protein |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNRHR | gonadotropin-releasing hormone receptor |
| GOLGA8A | golgin A8 family, member A |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IL2RG | interleukin 2 receptor, gamma |
| INADL | InaD-like (Drosophila) |
| IRF4 | interferon regulatory factor 4 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KIF5A | kinesin family member 5A |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LAMA4 | laminin, alpha 4 |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LILRP2 | leukocyte immunoglobulin-like receptor pseudogene 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAX | MYC associated factor X |
| MIER2 | mesoderm induction early response 1, family member 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PDLIM3 | PDZ and LIM domain 3 |
| PER1 | period circadian clock 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| RAB11B | RAB11B, member RAS oncogene family |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF122 | ring finger protein 122 |
| RUNX1 | runt-related transcription factor 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SH2D3A | SH2 domain containing 3A |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC6A16 | solute carrier family 6, member 16 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPRR1A | small proline-rich protein 1A |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| THRB | thyroid hormone receptor, beta |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPMT | thiopurine S-methyltransferase |
| TRD | T cell receptor delta locus |
| TRIM2 | tripartite motif containing 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WSCD1 | WSC domain containing 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF551 | zinc finger protein 551 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAPRIN2 | caprin family member 2 |
| CBR4 | carbonyl reductase 4 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEL | carboxyl ester lipase |
| CEP131 | centrosomal protein 131kDa |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 |
| CLIC2 | chloride intracellular channel 2 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC6 | excision repair cross-complementation group 6 |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GSTA4 | glutathione S-transferase alpha 4 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2AK | histone cluster 1, H2ak |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| HYI | hydroxypyruvate isomerase (putative) |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT81 | intraflagellar transport 81 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| KRT13 | keratin 13, type I |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| METTL16 | methyltransferase like 16 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MXD3 | MAX dimerization protein 3 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDHA9 | protocadherin alpha 9 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRDM14 | PR domain containing 14 |
| PROL1 | proline rich, lacrimal 1 |
| PRSS50 | protease, serine, 50 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RARS | arginyl-tRNA synthetase |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF25 | ring finger protein 25 |
| SESN1 | sestrin 1 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| STRA6 | stimulated by retinoic acid 6 |
| TESC | tescalcin |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM57 | transmembrane protein 57 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TOM1 | target of myb1 (chicken) |
| TRIM5 | tripartite motif containing 5 |
| TTBK2 | tau tubulin kinase 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBTD1 | ubiquitin domain containing 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR91 | WD repeat domain 91 |
| ZNF35 | zinc finger protein 35 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF428 | zinc finger protein 428 |
| ZNF446 | zinc finger protein 446 |
| ZNF516 | zinc finger protein 516 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
