| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the megestrol-6667 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANGPTL4 | angiopoietin-like 4 |
| APOD | apolipoprotein D |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| AURKC | aurora kinase C |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CACFD1 | calcium channel flower domain containing 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACYBP | calcyclin binding protein |
| CCDC181 | coiled-coil domain containing 181 |
| COBL | cordon-bleu WH2 repeat protein |
| COMMD4 | COMM domain containing 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DGCR6L | DiGeorge syndrome critical region gene 6-like |
| DTNA | dystrobrevin, alpha |
| DTNB | dystrobrevin, beta |
| EDN3 | endothelin 3 |
| EED | embryonic ectoderm development |
| EGR1 | early growth response 1 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPHB1 | EPH receptor B1 |
| ESR1 | estrogen receptor 1 |
| ETV1 | ets variant 1 |
| ETV6 | ets variant 6 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FOXO4 | forkhead box O4 |
| FRMD8 | FERM domain containing 8 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GH1 | growth hormone 1 |
| GPR15 | G protein-coupled receptor 15 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HNF1B | HNF1 homeobox B |
| HOMER3 | homer scaffolding protein 3 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLHL22 | kelch-like family member 22 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMTK2 | lemur tyrosine kinase 2 |
| LOXL3 | lysyl oxidase-like 3 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MORC1 | MORC family CW-type zinc finger 1 |
| MORN1 | MORN repeat containing 1 |
| MYO9B | myosin IXB |
| NCALD | neurocalcin delta |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| OGFR | opioid growth factor receptor |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| OR7C1 | olfactory receptor, family 7, subfamily C, member 1 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCDH9 | protocadherin 9 |
| PCDHB3 | protocadherin beta 3 |
| PCNX | pecanex homolog (Drosophila) |
| PCP4 | Purkinje cell protein 4 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PRMT2 | protein arginine methyltransferase 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RB1 | retinoblastoma 1 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RNF122 | ring finger protein 122 |
| SIRT4 | sirtuin 4 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TADA3 | transcriptional adaptor 3 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBX1 | T-box 1 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF516 | zinc finger protein 516 |
| ZNF74 | zinc finger protein 74 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ALPK1 | alpha-kinase 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CASZ1 | castor zinc finger 1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD101 | CD101 molecule |
| CD82 | CD82 molecule |
| CENPO | centromere protein O |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| FAM53B | family with sequence similarity 53, member B |
| FBRS | fibrosin |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GAS8 | growth arrest-specific 8 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRAMD1C | GRAM domain containing 1C |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H1D | histone cluster 1, H1d |
| HOMER2 | homer scaffolding protein 2 |
| HOXA1 | homeobox A1 |
| HOXC10 | homeobox C10 |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB7 | integrin, beta 7 |
| KIAA1107 | KIAA1107 |
| KIAA1456 | KIAA1456 |
| KIF13B | kinesin family member 13B |
| KIRREL | kin of IRRE like (Drosophila) |
| LOC257152 | uncharacterized LOC257152 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP1S | microtubule-associated protein 1S |
| MEGF8 | multiple EGF-like-domains 8 |
| MEIS1 | Meis homeobox 1 |
| MGP | matrix Gla protein |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRSS22 | protease, serine, 22 |
| RGCC | regulator of cell cycle |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCG5 | secretogranin V |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SETBP1 | SET binding protein 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SYNPO | synaptopodin |
| THBS3 | thrombospondin 3 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM156 | transmembrane protein 156 |
| TMEM180 | transmembrane protein 180 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| WDR33 | WD repeat domain 33 |
| WDR91 | WD repeat domain 91 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF141 | zinc finger protein 141 |
| ZNF219 | zinc finger protein 219 |
| ZNF747 | zinc finger protein 747 |
