meglumine-3068 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the meglumine-3068 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACVR1B activin A receptor, type IB
ADD2 adducin 2 (beta)
ADORA1 adenosine A1 receptor
ADRA2C adrenoceptor alpha 2C
AK5 adenylate kinase 5
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOL1 apolipoprotein L, 1
ARRB1 arrestin, beta 1
ATAT1 alpha tubulin acetyltransferase 1
BGN biglycan
BMP8B bone morphogenetic protein 8b
CARD10 caspase recruitment domain family, member 10
CD300A CD300a molecule
CDON cell adhesion associated, oncogene regulated
CHN2 chimerin 2
CLCF1 cardiotrophin-like cytokine factor 1
COMT catechol-O-methyltransferase
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CREBBP CREB binding protein
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGCR8 DGCR8 microprocessor complex subunit
DICER1 dicer 1, ribonuclease type III
DPEP2 dipeptidase 2
DRD2 dopamine receptor D2
E2F5 E2F transcription factor 5, p130-binding
EFNB3 ephrin-B3
EGF epidermal growth factor
EPN2 epsin 2
ESR1 estrogen receptor 1
FAM106A family with sequence similarity 106, member A
FAM65B family with sequence similarity 65, member B
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGD1 FYVE, RhoGEF and PH domain containing 1
GDF2 growth differentiation factor 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNLY granulysin
GPR182 G protein-coupled receptor 182
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GTPBP1 GTP binding protein 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXD9 homeobox D9
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
ING2 inhibitor of growth family, member 2
INO80B INO80 complex subunit B
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGA6 integrin, alpha 6
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KCTD2 potassium channel tetramerization domain containing 2
KIAA0513 KIAA0513
LECT1 leukocyte cell derived chemotaxin 1
MAP4 microtubule-associated protein 4
MATN1 matrilin 1, cartilage matrix protein
MLXIPL MLX interacting protein-like
PENK proenkephalin
POU5F1P4 POU class 5 homeobox 1 pseudogene 4
PPP1R17 protein phosphatase 1, regulatory subunit 17
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTCRA pre T-cell antigen receptor alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD52 RAD52 homolog (S. cerevisiae)
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
REPS1 RALBP1 associated Eps domain containing 1
RGS12 regulator of G-protein signaling 12
RUNX2 runt-related transcription factor 2
RYR2 ryanodine receptor 2 (cardiac)
SAA3P serum amyloid A3 pseudogene
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SEZ6L seizure related 6 homolog (mouse)-like
SIRT3 sirtuin 3
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SPAG1 sperm associated antigen 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SSX7 synovial sarcoma, X breakpoint 7
STOML1 stomatin (EPB72)-like 1
TAGLN3 transgelin 3
THRB thyroid hormone receptor, beta
THSD7A thrombospondin, type I, domain containing 7A
THTPA thiamine triphosphatase
TSPAN2 tetraspanin 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WWOX WW domain containing oxidoreductase
YIPF2 Yip1 domain family, member 2
ZNF185 zinc finger protein 185 (LIM domain)
ZNF205 zinc finger protein 205
ZNF639 zinc finger protein 639
ZNF688 zinc finger protein 688
ZNF749 zinc finger protein 749

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ANGEL1 angel homolog 1 (Drosophila)
ART1 ADP-ribosyltransferase 1
BCL2L2 BCL2-like 2
BEND5 BEN domain containing 5
C11ORF30 chromosome 11 open reading frame 30
C1RL complement component 1, r subcomponent-like
CD180 CD180 molecule
CD70 CD70 molecule
CEP295 centrosomal protein 295kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL4A2 collagen, type IV, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CROT carnitine O-octanoyltransferase
CRYL1 crystallin, lambda 1
CTSD cathepsin D
CXCL2 chemokine (C-X-C motif) ligand 2
DNMBP dynamin binding protein
FBRS fibrosin
FHL3 four and a half LIM domains 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPATCH2L G patch domain containing 2-like
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSDMD gasdermin D
GTPBP3 GTP binding protein 3 (mitochondrial)
HIST1H1B histone cluster 1, H1b
HIST1H2BN histone cluster 1, H2bn
HIST1H3G histone cluster 1, H3g
HYAL2 hyaluronoglucosaminidase 2
IPO13 importin 13
KIF24 kinesin family member 24
KLK5 kallikrein-related peptidase 5
L2HGDH L-2-hydroxyglutarate dehydrogenase
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MAGED1 melanoma antigen family D1
MAGEH1 melanoma antigen family H1
MEFV Mediterranean fever
METTL2B methyltransferase like 2B
MIR22HG MIR22 host gene
MKL2 MKL/myocardin-like 2
MPZ myelin protein zero
NABP2 nucleic acid binding protein 2
NINJ2 ninjurin 2
NOL10 nucleolar protein 10
NXPE3 neurexophilin and PC-esterase domain family, member 3
PERP PERP, TP53 apoptosis effector
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PTH2R parathyroid hormone 2 receptor
RAB23 RAB23, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCAN3 RCAN family member 3
RIN1 Ras and Rab interactor 1
RNF121 ring finger protein 121
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SKA1 spindle and kinetochore associated complex subunit 1
SLC35F6 solute carrier family 35, member F6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPINT1 serine peptidase inhibitor, Kunitz type 1
STAT5A signal transducer and activator of transcription 5A
STX1A syntaxin 1A (brain)
SYNC syncoilin, intermediate filament protein
TBX19 T-box 19
TGFBR3 transforming growth factor, beta receptor III
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMC5 transmembrane channel-like 5
TMEM140 transmembrane protein 140
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRAF1 TNF receptor-associated factor 1
TRIM36 tripartite motif containing 36
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBG2 tubulin, gamma 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UCN urocortin
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XYLT2 xylosyltransferase II
ZC2HC1A zinc finger, C2HC-type containing 1A
ZHX2 zinc fingers and homeoboxes 2
ZNF134 zinc finger protein 134
ZNF428 zinc finger protein 428
ZNF611 zinc finger protein 611
ZSCAN16 zinc finger and SCAN domain containing 16