meglumine-5285 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the meglumine-5285 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACTG2 actin, gamma 2, smooth muscle, enteric
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKIP1 A kinase (PRKA) interacting protein 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGAP33 Rho GTPase activating protein 33
ASF1A anti-silencing function 1A histone chaperone
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BMP1 bone morphogenetic protein 1
BTBD7 BTB (POZ) domain containing 7
C17ORF80 chromosome 17 open reading frame 80
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF29 chromosome 22 open reading frame 29
C8ORF60 chromosome 8 open reading frame 60
CASD1 CAS1 domain containing 1
CD82 CD82 molecule
COCH cochlin
CPPED1 calcineurin-like phosphoesterase domain containing 1
DCAF15 DDB1 and CUL4 associated factor 15
DSCAM Down syndrome cell adhesion molecule
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EML3 echinoderm microtubule associated protein like 3
EPHA1 EPH receptor A1
EPHB3 EPH receptor B3
ETNK1 ethanolamine kinase 1
FCHO1 FCH domain only 1
FKBP10 FK506 binding protein 10, 65 kDa
FXR2 fragile X mental retardation, autosomal homolog 2
H2AFX H2A histone family, member X
HCFC1 host cell factor C1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2BC histone cluster 1, H2bc
HLA-B major histocompatibility complex, class I, B
HMGN5 high mobility group nucleosome binding domain 5
HOXC10 homeobox C10
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IP6K1 inositol hexakisphosphate kinase 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
JAG2 jagged 2
JRK Jrk homolog (mouse)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0485 uncharacterized LOC57235
LPPR2 lipid phosphate phosphatase-related protein type 2
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAPK14 mitogen-activated protein kinase 14
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MMP19 matrix metallopeptidase 19
MTAP methylthioadenosine phosphorylase
NAAA N-acylethanolamine acid amidase
NDE1 nudE neurodevelopment protein 1
NFX1 nuclear transcription factor, X-box binding 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NMT1 N-myristoyltransferase 1
NPFFR1 neuropeptide FF receptor 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSBPL2 oxysterol binding protein-like 2
PAOX polyamine oxidase (exo-N4-amino)
PDE4DIP phosphodiesterase 4D interacting protein
PGPEP1 pyroglutamyl-peptidase I
PLCG1 phospholipase C, gamma 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLL polymerase (DNA directed), lambda
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RIPK4 receptor-interacting serine-threonine kinase 4
RPL10 ribosomal protein L10
RPL7 ribosomal protein L7
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SETD8 SET domain containing (lysine methyltransferase) 8
SIN3B SIN3 transcription regulator family member B
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPTAN1 spectrin, alpha, non-erythrocytic 1
STK10 serine/threonine kinase 10
STX2 syntaxin 2
SUGP2 SURP and G patch domain containing 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNJ2 synaptojanin 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TEAD3 TEA domain family member 3
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TMEM63A transmembrane protein 63A
TMPRSS3 transmembrane protease, serine 3
TP53I11 tumor protein p53 inducible protein 11
TRIM2 tripartite motif containing 2
TRIM25 tripartite motif containing 25
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WIZ widely interspaced zinc finger motifs
ZBTB48 zinc finger and BTB domain containing 48
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
BPGM 2,3-bisphosphoglycerate mutase
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF49 chromosome 11 open reading frame 49
C16ORF59 chromosome 16 open reading frame 59
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA2 calmodulin binding transcription activator 2
CAPG capping protein (actin filament), gelsolin-like
CAPN15 calpain 15
CBX7 chromobox homolog 7
CCDC94 coiled-coil domain containing 94
CCS copper chaperone for superoxide dismutase
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CEP97 centrosomal protein 97kDa
CLK1 CDC-like kinase 1
COQ3 coenzyme Q3 methyltransferase
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DDIT3 DNA-damage-inducible transcript 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND1A DENN/MADD domain containing 1A
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DUSP22 dual specificity phosphatase 22
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFHD1 EF-hand domain family, member D1
ELP3 elongator acetyltransferase complex subunit 3
FSD1 fibronectin type III and SPRY domain containing 1
FYCO1 FYVE and coiled-coil domain containing 1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNL1 guanine nucleotide binding protein-like 1
GRAMD3 GRAM domain containing 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIRIP3 HIRA interacting protein 3
HIST1H1D histone cluster 1, H1d
HIST2H2AA3 histone cluster 2, H2aa3
IDI2-AS1 IDI2 antisense RNA 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT13 keratin 13, type I
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MED15 mediator complex subunit 15
MEIS2 Meis homeobox 2
MSX1 msh homeobox 1
NDRG1 N-myc downstream regulated 1
NPY1R neuropeptide Y receptor Y1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NT5DC2 5'-nucleotidase domain containing 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PILRB paired immunoglobin-like type 2 receptor beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD3 phospholipase D family, member 3
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
PTK6 protein tyrosine kinase 6
PTOV1 prostate tumor overexpressed 1
PYGL phosphorylase, glycogen, liver
RAB17 RAB17, member RAS oncogene family
RCOR3 REST corepressor 3
RFTN1 raftlin, lipid raft linker 1
RIN2 Ras and Rab interactor 2
RINT1 RAD50 interactor 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF123 ring finger protein 123
RPL23AP7 ribosomal protein L23a pseudogene 7
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F6 solute carrier family 35, member F6
SMA4 glucuronidase, beta pseudogene
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNIP1 Smad nuclear interacting protein 1
SPIDR scaffolding protein involved in DNA repair
SQRDL sulfide quinone reductase-like (yeast)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK16 serine/threonine kinase 16
THAP7 THAP domain containing 7
TMCO3 transmembrane and coiled-coil domains 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TXLNG taxilin gamma
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
USP36 ubiquitin specific peptidase 36
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR46 WD repeat domain 46
YEATS2 YEATS domain containing 2
ZNF329 zinc finger protein 329
ZNF35 zinc finger protein 35
ZNF492 zinc finger protein 492
ZNF639 zinc finger protein 639
ZNF665 zinc finger protein 665
ZNF767P zinc finger family member 767, pseudogene