meglumine-6685 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the meglumine-6685 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADRA1A adrenoceptor alpha 1A
ANXA2P1 annexin A2 pseudogene 1
ARHGAP28 Rho GTPase activating protein 28
BMP8A bone morphogenetic protein 8a
C3ORF36 chromosome 3 open reading frame 36
CARD9 caspase recruitment domain family, member 9
CD209 CD209 molecule
CD6 CD6 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLCA2 chloride channel accessory 2
COL6A1 collagen, type VI, alpha 1
COMP cartilage oligomeric matrix protein
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYSLTR1 cysteinyl leukotriene receptor 1
DKKL1 dickkopf-like 1
EFCAB11 EF-hand calcium binding domain 11
FES FES proto-oncogene, tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FUBP1 far upstream element (FUSE) binding protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAS8 growth arrest-specific 8
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GRM8 glutamate receptor, metabotropic 8
GTPBP1 GTP binding protein 1
GZMK granzyme K (granzyme 3; tryptase II)
HCFC1 host cell factor C1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL12RB1 interleukin 12 receptor, beta 1
IRX4 iroquois homeobox 4
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KIAA1467 KIAA1467
KIF13A kinesin family member 13A
KLHL22 kelch-like family member 22
KLHL23 kelch-like family member 23
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMOD1 leiomodin 1 (smooth muscle)
LRRC48 leucine rich repeat containing 48
LY9 lymphocyte antigen 9
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBNL1 muscleblind-like splicing regulator 1
MCF2 MCF.2 cell line derived transforming sequence
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGC2889 uncharacterized protein MGC2889
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MYCNOS MYCN opposite strand
NCR1 natural cytotoxicity triggering receptor 1
NEUROD1 neuronal differentiation 1
NEUROG2 neurogenin 2
NPAS1 neuronal PAS domain protein 1
NPR1 natriuretic peptide receptor 1
NRP2 neuropilin 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PBOV1 prostate and breast cancer overexpressed 1
PHF7 PHD finger protein 7
PKD2L2 polycystic kidney disease 2-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PVALB parvalbumin
PVR poliovirus receptor
PXN paxillin
RASAL1 RAS protein activator like 1 (GAP1 like)
RBM12B-AS1 RBM12B antisense RNA 1
RGS12 regulator of G-protein signaling 12
RGS6 regulator of G-protein signaling 6
RUNX1 runt-related transcription factor 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC39A9 solute carrier family 39, member 9
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
SMG7-AS1 SMG7 antisense RNA 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNED1 sushi, nidogen and EGF-like domains 1
SPAG8 sperm associated antigen 8
SRPX2 sushi-repeat containing protein, X-linked 2
SSX1 synovial sarcoma, X breakpoint 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
THEMIS2 thymocyte selection associated family member 2
TLX2 T-cell leukemia homeobox 2
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP63 tumor protein p63
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VCL vinculin
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XYLB xylulokinase homolog (H. influenzae)
ZNF117 zinc finger protein 117
ZNF223 zinc finger protein 223
ZNF407 zinc finger protein 407
ZNF440 zinc finger protein 440
ZNF484 zinc finger protein 484
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AMDHD2 amidohydrolase domain containing 2
ARL15 ADP-ribosylation factor-like 15
ATP10D ATPase, class V, type 10D
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C1ORF105 chromosome 1 open reading frame 105
C9ORF78 chromosome 9 open reading frame 78
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASZ1 castor zinc finger 1
CDH7 cadherin 7, type 2
CEMIP cell migration inducing protein, hyaluronan binding
CEP112 centrosomal protein 112kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCN5 chloride channel, voltage-sensitive 5
CLDN14 claudin 14
CLDN8 claudin 8
COQ3 coenzyme Q3 methyltransferase
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL2 chemokine (C-X-C motif) ligand 2
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND1B DENN/MADD domain containing 1B
DTX4 deltex 4, E3 ubiquitin ligase
FAM50B family with sequence similarity 50, member B
FBXL7 F-box and leucine-rich repeat protein 7
GPALPP1 GPALPP motifs containing 1
GPNMB glycoprotein (transmembrane) nmb
GPX2 glutathione peroxidase 2
GUSBP3 glucuronidase, beta pseudogene 3
HEATR3 HEAT repeat containing 3
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST2H2AA3 histone cluster 2, H2aa3
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOOK1 hook microtubule-tethering protein 1
IER3IP1 immediate early response 3 interacting protein 1
IL17RA interleukin 17 receptor A
ISL1 ISL LIM homeobox 1
KDM8 lysine (K)-specific demethylase 8
KIAA1107 KIAA1107
KIRREL kin of IRRE like (Drosophila)
LOC100286895 cell division cycle 27 homolog pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MCC mutated in colorectal cancers
MOCS3 molybdenum cofactor synthesis 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL52 mitochondrial ribosomal protein L52
MSRA methionine sulfoxide reductase A
NBEA neurobeachin
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PARM1 prostate androgen-regulated mucin-like protein 1
PER3 period circadian clock 3
PLCD1 phospholipase C, delta 1
PMCH pro-melanin-concentrating hormone
POLL polymerase (DNA directed), lambda
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRR14L proline rich 14-like
PRR4 proline rich 4 (lacrimal)
QSER1 glutamine and serine rich 1
RAI2 retinoic acid induced 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RGS19 regulator of G-protein signaling 19
RPL23AP32 ribosomal protein L23a pseudogene 32
RUSC2 RUN and SH3 domain containing 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SERINC5 serine incorporator 5
SKI SKI proto-oncogene
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TMEM242 transmembrane protein 242
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRIM52 tripartite motif containing 52
UBQLN4 ubiquilin 4
USP6 ubiquitin specific peptidase 6
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZBTB39 zinc finger and BTB domain containing 39
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480
ZNF652 zinc finger protein 652