mek Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

118 genes co-occuring with the biological term mek in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APP amyloid beta (A4) precursor protein
AR androgen receptor
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL15 chemokine (C-C motif) ligand 15
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CIRBP cold inducible RNA binding protein
CTGF connective tissue growth factor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DNMT1 DNA (cytosine-5-)-methyltransferase 1
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ELK1 ELK1, member of ETS oncogene family
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGFR2 fibroblast growth factor receptor 2
FOXM1 forkhead box M1
GH1 growth hormone 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GRM3 glutamate receptor, metabotropic 3
HAVCR2 hepatitis A virus cellular receptor 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSF1 heat shock transcription factor 1
HSPA8 heat shock 70kDa protein 8
IGF1 insulin-like growth factor 1 (somatomedin C)
IL17A interleukin 17A
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK3 Janus kinase 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KSR2 kinase suppressor of ras 2
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LOX lysyl oxidase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAT2B methionine adenosyltransferase II, beta
MCL1 myeloid cell leukemia 1
MIR17 microRNA 17
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLANA melan-A
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCOR2 nuclear receptor corepressor 2
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSM oncostatin M
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP1 poly (ADP-ribose) polymerase 1
PDGFA platelet-derived growth factor alpha polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PEBP4 phosphatidylethanolamine-binding protein 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RARA retinoic acid receptor, alpha
RND3 Rho family GTPase 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOD1 superoxide dismutase 1, soluble
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STK11 serine/threonine kinase 11
SUMO1 small ubiquitin-like modifier 1
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
VEGFA vascular endothelial growth factor A
WISP1 WNT1 inducible signaling pathway protein 1