melanocytic nevus Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A oval and round, colored (usually medium-to dark brown, reddish brown, or flesh colored) lesion. Typically, a melanocytic nevus is less than 6 mm in diameter, but may be much smaller or larger. (Human Phenotype Ontology, HP_0000995)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000995
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Genes

39 genes associated with the melanocytic nevus phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
COL3A1 collagen, type III, alpha 1
ERF Ets2 repressor factor
FGF3 fibroblast growth factor 3
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FKBP10 FK506 binding protein 10, 65 kDa
HPS1 Hermansky-Pudlak syndrome 1
HRAS Harvey rat sarcoma viral oncogene homolog
KAT6B K(lysine) acetyltransferase 6B
KLLN killin, p53-regulated DNA replication inhibitor
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT1 keratin 1, type II
KRT10 keratin 10, type I
LEMD3 LEM domain containing 3
MPL MPL proto-oncogene, thrombopoietin receptor
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDE4D phosphodiesterase 4D, cAMP-specific
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBM28 RNA binding motif protein 28
RIT1 Ras-like without CAAX 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SOS1 son of sevenless homolog 1 (Drosophila)
STK11 serine/threonine kinase 11
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TP63 tumor protein p63
TYR tyrosinase