| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the melatonin-2431 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK4 | aarF domain containing kinase 4 |
| ADCY6 | adenylate cyclase 6 |
| ADCY9 | adenylate cyclase 9 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AFF1 | AF4/FMR2 family, member 1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| APOD | apolipoprotein D |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATXN3 | ataxin 3 |
| AURKA | aurora kinase A |
| BCL6 | B-cell CLL/lymphoma 6 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CCDC57 | coiled-coil domain containing 57 |
| CD9 | CD9 molecule |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CEP164 | centrosomal protein 164kDa |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CNN3 | calponin 3, acidic |
| COL18A1 | collagen, type XVIII, alpha 1 |
| CPNE1 | copine I |
| CPTP | ceramide-1-phosphate transfer protein |
| CRAT | carnitine O-acetyltransferase |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DLG3 | discs, large homolog 3 (Drosophila) |
| ECE1 | endothelin converting enzyme 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ESRRA | estrogen-related receptor alpha |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBLN1 | fibulin 1 |
| FBXO31 | F-box protein 31 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FKBP1A | FK506 binding protein 1A, 12kDa |
| FOXP3 | forkhead box P3 |
| GNMT | glycine N-methyltransferase |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HDAC11 | histone deacetylase 11 |
| HN1L | hematological and neurological expressed 1-like |
| IDS | iduronate 2-sulfatase |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| METTL16 | methyltransferase like 16 |
| MRC2 | mannose receptor, C type 2 |
| MTSS1 | metastasis suppressor 1 |
| NEBL | nebulette |
| NOX1 | NADPH oxidase 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUP188 | nucleoporin 188kDa |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLCE1 | phospholipase C, epsilon 1 |
| PLK3 | polo-like kinase 3 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRR7 | proline rich 7 (synaptic) |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB13 | RAB13, member RAS oncogene family |
| RAB35 | RAB35, member RAS oncogene family |
| REEP1 | receptor accessory protein 1 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RFPL3 | ret finger protein-like 3 |
| RNASE3 | ribonuclease, RNase A family, 3 |
| RPL10L | ribosomal protein L10-like |
| RPS2P45 | ribosomal protein S2 pseudogene 45 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RXRB | retinoid X receptor, beta |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SH2D3A | SH2 domain containing 3A |
| SHOX2 | short stature homeobox 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SMAD5 | SMAD family member 5 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYCP2 | synaptonemal complex protein 2 |
| TEX40 | testis expressed 40 |
| THSD7A | thrombospondin, type I, domain containing 7A |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TNPO2 | transportin 2 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| UNC45A | unc-45 homolog A (C. elegans) |
| ZFHX4 | zinc finger homeobox 4 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZIM2 | zinc finger, imprinted 2 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BPI | bactericidal/permeability-increasing protein |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCNT1 | cyclin T1 |
| CDK3 | cyclin-dependent kinase 3 |
| CENPB | centromere protein B, 80kDa |
| CEP97 | centrosomal protein 97kDa |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNTLN | centlein, centrosomal protein |
| COL15A1 | collagen, type XV, alpha 1 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTSV | cathepsin V |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DPEP2 | dipeptidase 2 |
| FGF23 | fibroblast growth factor 23 |
| FGL1 | fibrinogen-like 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| HAMP | hepcidin antimicrobial peptide |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BN | histone cluster 1, H2bn |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HS1BP3 | HCLS1 binding protein 3 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IFNA14 | interferon, alpha 14 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IPO8 | importin 8 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| LOC257152 | uncharacterized LOC257152 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MIR22HG | MIR22 host gene |
| MRAS | muscle RAS oncogene homolog |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NCKAP1L | NCK-associated protein 1-like |
| NIPAL2 | NIPA-like domain containing 2 |
| NOTCH4 | notch 4 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PHACTR1 | phosphatase and actin regulator 1 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PNOC | prepronociceptin |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PSKH1 | protein serine kinase H1 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| QSER1 | glutamine and serine rich 1 |
| RAB33A | RAB33A, member RAS oncogene family |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SPATA20 | spermatogenesis associated 20 |
| SPRR2B | small proline-rich protein 2B |
| STEAP3 | STEAP family member 3, metalloreductase |
| STX11 | syntaxin 11 |
| THEM6 | thioesterase superfamily member 6 |
| TNS2 | tensin 2 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN2 | tetraspanin 2 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUFT1 | tuftelin 1 |
| VEGFC | vascular endothelial growth factor C |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR13 | WD repeat domain 13 |
| WDR82 | WD repeat domain 82 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF701 | zinc finger protein 701 |