melatonin-3293 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the melatonin-3293 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX15 arachidonate 15-lipoxygenase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ART1 ADP-ribosyltransferase 1
ARTN artemin
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
C8B complement component 8, beta polypeptide
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CD52 CD52 molecule
CD58 CD58 molecule
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLCN6 chloride channel, voltage-sensitive 6
CLCN7 chloride channel, voltage-sensitive 7
CORT cortistatin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXADR coxsackie virus and adenovirus receptor
CXCR2 chemokine (C-X-C motif) receptor 2
DAAM2 dishevelled associated activator of morphogenesis 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DTNA dystrobrevin, alpha
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EZR ezrin
F3 coagulation factor III (thromboplastin, tissue factor)
FAM174B family with sequence similarity 174, member B
FCMR Fc fragment of IgM receptor
FKBP10 FK506 binding protein 10, 65 kDa
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL2 FOS-like antigen 2
FOXN3 forkhead box N3
FRMD1 FERM domain containing 1
GLRA1 glycine receptor, alpha 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPC1 glypican 1
HFE hemochromatosis
HIST1H4F histone cluster 1, H4f
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
HR hair growth associated
HSF4 heat shock transcription factor 4
ICOS inducible T-cell co-stimulator
INPP1 inositol polyphosphate-1-phosphatase
ITGB8 integrin, beta 8
ITM2C integral membrane protein 2C
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1324 KIAA1324
KRT24 keratin 24, type I
LINC00341 long intergenic non-protein coding RNA 341
LRP12 low density lipoprotein receptor-related protein 12
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MOGAT2 monoacylglycerol O-acyltransferase 2
MSMB microseminoprotein, beta-
NDRG2 NDRG family member 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NPM3 nucleophosmin/nucleoplasmin 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OSBPL2 oxysterol binding protein-like 2
OVOL1 ovo-like zinc finger 1
PCDH7 protocadherin 7
PDLIM7 PDZ and LIM domain 7 (enigma)
PICK1 protein interacting with PRKCA 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLTP phospholipid transfer protein
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PRB3 proline-rich protein BstNI subfamily 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTCRA pre T-cell antigen receptor alpha
PURA purine-rich element binding protein A
RAD51B RAD51 paralog B
RB1 retinoblastoma 1
RBM8A RNA binding motif protein 8A
REM1 RAS (RAD and GEM)-like GTP-binding 1
RND1 Rho family GTPase 1
RNF31 ring finger protein 31
RPS2 ribosomal protein S2
RPS4Y1 ribosomal protein S4, Y-linked 1
RUFY3 RUN and FYVE domain containing 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNN stannin
SPHK2 sphingosine kinase 2
STK16 serine/threonine kinase 16
TBX5 T-box 5
TLDC1 TBC/LysM-associated domain containing 1
TRIM36 tripartite motif containing 36
TUBA4B tubulin, alpha 4b
TXNL4B thioredoxin-like 4B
WDR33 WD repeat domain 33
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZMAT4 zinc finger, matrin-type 4
ZNF770 zinc finger protein 770
ZNF862 zinc finger protein 862
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAT1 adenosine deaminase, tRNA-specific 1
AES amino-terminal enhancer of split
AFAP1 actin filament associated protein 1
ALPK1 alpha-kinase 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC6 armadillo repeat containing 6
ARRB2 arrestin, beta 2
AUP1 ancient ubiquitous protein 1
AUTS2 autism susceptibility candidate 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
C16ORF45 chromosome 16 open reading frame 45
C8ORF44 chromosome 8 open reading frame 44
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK18 cyclin-dependent kinase 18
CERS4 ceramide synthase 4
CIDEB cell death-inducing DFFA-like effector b
CSTA cystatin A (stefin A)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DAGLA diacylglycerol lipase, alpha
DENND4C DENN/MADD domain containing 4C
DIXDC1 DIX domain containing 1
DMTN dematin actin binding protein
DUSP2 dual specificity phosphatase 2
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
FRK fyn-related Src family tyrosine kinase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS2 HAUS augmin-like complex, subunit 2
HPN hepsin
HYI hydroxypyruvate isomerase (putative)
IFI6 interferon, alpha-inducible protein 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM7A lysine (K)-specific demethylase 7A
KIAA0125 KIAA0125
KIF3B kinesin family member 3B
LARP6 La ribonucleoprotein domain family, member 6
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRRC6 leucine rich repeat containing 6
LZTR1 leucine-zipper-like transcription regulator 1
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
MRPL44 mitochondrial ribosomal protein L44
MTCP1 mature T-cell proliferation 1
MYBBP1A MYB binding protein (P160) 1a
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NT5E 5'-nucleotidase, ecto (CD73)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
PC pyruvate carboxylase
PHACTR4 phosphatase and actin regulator 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRR14L proline rich 14-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB30 RAB30, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPL10L ribosomal protein L10-like
S100A6 S100 calcium binding protein A6
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SETD1A SET domain containing 1A
SETD1B SET domain containing 1B
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIDT1 SID1 transmembrane family, member 1
SIRT6 sirtuin 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLN sarcolipin
SUN2 Sad1 and UNC84 domain containing 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TDRD1 tudor domain containing 1
TMEM121 transmembrane protein 121
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSGA10 testis specific, 10
VGF VGF nerve growth factor inducible
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZIC3 Zic family member 3
ZNF160 zinc finger protein 160
ZNF428 zinc finger protein 428
ZNF606 zinc finger protein 606
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721