| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the melatonin-5393 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 |
| AGFG2 | ArfGAP with FG repeats 2 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARTN | artemin |
| ATF5 | activating transcription factor 5 |
| ATG3 | autophagy related 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C19ORF57 | chromosome 19 open reading frame 57 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC132 | coiled-coil domain containing 132 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD83 | CD83 molecule |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CEP290 | centrosomal protein 290kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL1A1 | collagen, type I, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPE | carboxypeptidase E |
| CREBZF | CREB/ATF bZIP transcription factor |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DOCK5 | dedicator of cytokinesis 5 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EDNRB | endothelin receptor type B |
| FLJ11292 | |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GLUD2 | glutamate dehydrogenase 2 |
| GM2A | GM2 ganglioside activator |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPR27 | G protein-coupled receptor 27 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL1RAP | interleukin 1 receptor accessory protein |
| JAM3 | junctional adhesion molecule 3 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KLHL22 | kelch-like family member 22 |
| KLHL25 | kelch-like family member 25 |
| KRT32 | keratin 32, type I |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| NFYA | nuclear transcription factor Y, alpha |
| NPFF | neuropeptide FF-amide peptide precursor |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUP188 | nucleoporin 188kDa |
| NXPH4 | neurexophilin 4 |
| PCDH7 | protocadherin 7 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHF3 | PHD finger protein 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLK4 | polo-like kinase 4 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PQBP1 | polyglutamine binding protein 1 |
| PRAMEF11 | PRAME family member 11 |
| PRKCE | protein kinase C, epsilon |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PYY | peptide YY |
| RAB30 | RAB30, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RND2 | Rho family GTPase 2 |
| S100A11 | S100 calcium binding protein A11 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIRT5 | sirtuin 5 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNX1 | sorting nexin 1 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STK3 | serine/threonine kinase 3 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TIGD6 | tigger transposable element derived 6 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPP1 | tripeptidyl peptidase I |
| TSPAN9 | tetraspanin 9 |
| ZFHX4 | zinc finger homeobox 4 |
| ZIC3 | Zic family member 3 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AEBP1 | AE binding protein 1 |
| AGO3 | argonaute RISC catalytic component 3 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOD | apolipoprotein D |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B9D2 | B9 protein domain 2 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CHM | choroideremia (Rab escort protein 1) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CTAGE9 | CTAGE family, member 9 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFNA3 | ephrin-A3 |
| ETNK2 | ethanolamine kinase 2 |
| ETV6 | ets variant 6 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HDAC5 | histone deacetylase 5 |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4F | histone cluster 1, H4f |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFT140 | intraflagellar transport 140 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0319L | KIAA0319-like |
| LAMA3 | laminin, alpha 3 |
| LHX1 | LIM homeobox 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MATN3 | matrilin 3 |
| MGC12488 | |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MVP | major vault protein |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| OLFML2A | olfactomedin-like 2A |
| PCDHB3 | protocadherin beta 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PGR | progesterone receptor |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PORCN | porcupine homolog (Drosophila) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRR4 | proline rich 4 (lacrimal) |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RNF39 | ring finger protein 39 |
| RPAP1 | RNA polymerase II associated protein 1 |
| S100A9 | S100 calcium binding protein A9 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SMIM14 | small integral membrane protein 14 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPAG4 | sperm associated antigen 4 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STIM1 | stromal interaction molecule 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TESC | tescalcin |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TLR5 | toll-like receptor 5 |
| TMEM104 | transmembrane protein 104 |
| TMEM180 | transmembrane protein 180 |
| TMEM212 | transmembrane protein 212 |
| TMEM57 | transmembrane protein 57 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPCN1 | two pore segment channel 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| UBOX5 | U-box domain containing 5 |
| UBTD1 | ubiquitin domain containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF516 | zinc finger protein 516 |
