| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the melatonin-6293 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| AIM1L | absent in melanoma 1-like |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| ATG10 | autophagy related 10 |
| BAIAP3 | BAI1-associated protein 3 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD58 | CD58 molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEP162 | centrosomal protein 162kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CLDN1 | claudin 1 |
| COPA | coatomer protein complex, subunit alpha |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDN | dendrin |
| DOCK9 | dedicator of cytokinesis 9 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| ESR1 | estrogen receptor 1 |
| ETNK2 | ethanolamine kinase 2 |
| FCMR | Fc fragment of IgM receptor |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLI2 | GLI family zinc finger 2 |
| GOLGA1 | golgin A1 |
| GPR15 | G protein-coupled receptor 15 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF2I | general transcription factor IIi |
| HGFAC | HGF activator |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HN1L | hematological and neurological expressed 1-like |
| HNMT | histamine N-methyltransferase |
| HOXB5 | homeobox B5 |
| HOXD1 | homeobox D1 |
| IFNA14 | interferon, alpha 14 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| INHBC | inhibin, beta C |
| IRF4 | interferon regulatory factor 4 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0922 | KIAA0922 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| LAMA4 | laminin, alpha 4 |
| LAMB4 | laminin, beta 4 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRRC48 | leucine rich repeat containing 48 |
| LTC4S | leukotriene C4 synthase |
| MATN1 | matrilin 1, cartilage matrix protein |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| MST1 | macrophage stimulating 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NME5 | NME/NM23 family member 5 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OSMR | oncostatin M receptor |
| PCNX | pecanex homolog (Drosophila) |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| POU4F1 | POU class 4 homeobox 1 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RARG | retinoic acid receptor, gamma |
| RGS12 | regulator of G-protein signaling 12 |
| RHOT2 | ras homolog family member T2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RREB1 | ras responsive element binding protein 1 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SIRT5 | sirtuin 5 |
| SLC25A30 | solute carrier family 25, member 30 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| STMN4 | stathmin-like 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAOK2 | TAO kinase 2 |
| TBX5 | T-box 5 |
| TBXA2R | thromboxane A2 receptor |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TOP3B | topoisomerase (DNA) III beta |
| TRADD | TNFRSF1A-associated via death domain |
| UBXN1 | UBX domain protein 1 |
| WIZ | widely interspaced zinc finger motifs |
| WWOX | WW domain containing oxidoreductase |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF44 | zinc finger protein 44 |
| ZNF516 | zinc finger protein 516 |
| ZNF528 | zinc finger protein 528 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| AGR2 | anterior gradient 2 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARRB2 | arrestin, beta 2 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BOLA1 | bolA family member 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C5 | complement component 5 |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC94 | coiled-coil domain containing 94 |
| CCS | copper chaperone for superoxide dismutase |
| CHEK2 | checkpoint kinase 2 |
| CHMP6 | charged multivesicular body protein 6 |
| CHPF | chondroitin polymerizing factor |
| CPA4 | carboxypeptidase A4 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EN2 | engrailed homeobox 2 |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FPGS | folylpolyglutamate synthase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR176 | G protein-coupled receptor 176 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3G | histone cluster 1, H3g |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMOX1 | heme oxygenase 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGFLR1 | IGF-like family receptor 1 |
| IRF9 | interferon regulatory factor 9 |
| KDM4D | lysine (K)-specific demethylase 4D |
| KLK5 | kallikrein-related peptidase 5 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCOLN1 | mucolipin 1 |
| MED15 | mediator complex subunit 15 |
| METTL2B | methyltransferase like 2B |
| MITF | microphthalmia-associated transcription factor |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1D | myosin ID |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PC | pyruvate carboxylase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE12 | phosphodiesterase 12 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLSCR4 | phospholipid scramblase 4 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PRKCD | protein kinase C, delta |
| PRR14L | proline rich 14-like |
| PRR3 | proline rich 3 |
| PRR7 | proline rich 7 (synaptic) |
| PYGB | phosphorylase, glycogen; brain |
| RASA2 | RAS p21 protein activator 2 |
| RBM42 | RNA binding motif protein 42 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNH1 | ribonuclease/angiogenin inhibitor 1 |
| RWDD3 | RWD domain containing 3 |
| S100A14 | S100 calcium binding protein A14 |
| SH2B2 | SH2B adaptor protein 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNX16 | sorting nexin 16 |
| SPATA2L | spermatogenesis associated 2-like |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TENM4 | teneurin transmembrane protein 4 |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TUBA3C | tubulin, alpha 3c |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| VEGFB | vascular endothelial growth factor B |
| ZNF177 | zinc finger protein 177 |
| ZNF197 | zinc finger protein 197 |
| ZNF253 | zinc finger protein 253 |
| ZNF611 | zinc finger protein 611 |
