melatonin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans. (Chemical Entities of Biological Interest Ontology, CHEBI_16796)
Similar Terms
Downloads & Tools

Genes

74 genes co-occuring with the biological term melatonin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ADRA1B adrenoceptor alpha 1B
ADRB1 adrenoceptor beta 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
APAF1 apoptotic peptidase activating factor 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMT acetylserotonin O-methyltransferase
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL5 chemokine (C-C motif) ligand 5
CLEC7A C-type lectin domain family 7, member A
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DDIT3 DNA-damage-inducible transcript 3
EDN1 endothelin 1
ESR1 estrogen receptor 1
FOXO1 forkhead box O1
GJA1 gap junction protein, alpha 1, 43kDa
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPR50 G protein-coupled receptor 50
HCRT hypocretin (orexin) neuropeptide precursor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSPB1 heat shock 27kDa protein 1
HTRA2 HtrA serine peptidase 2
IL1B interleukin 1, beta
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
KAT2B K(lysine) acetyltransferase 2B
LEP leptin
MAPK1 mitogen-activated protein kinase 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPDZ multiple PDZ domain protein
MPO myeloperoxidase
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NQO2 NAD(P)H dehydrogenase, quinone 2
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
PEA15 phosphoprotein enriched in astrocytes 15
PER1 period circadian clock 1
PER2 period circadian clock 2
PER3 period circadian clock 3
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAI1 retinoic acid induced 1
RARA retinoic acid receptor, alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS4 regulator of G-protein signaling 4
RORA RAR-related orphan receptor A
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNX2 runt-related transcription factor 2
SPHK1 sphingosine kinase 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNF tumor necrosis factor
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A