| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the memantine-2934 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD6 | abhydrolase domain containing 6 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AIF1 | allograft inflammatory factor 1 |
| AIM1L | absent in melanoma 1-like |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ATN1 | atrophin 1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
| BAIAP2 | BAI1-associated protein 2 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CABP2 | calcium binding protein 2 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC88A | coiled-coil domain containing 88A |
| CLEC4A | C-type lectin domain family 4, member A |
| CLTC | clathrin, heavy chain (Hc) |
| CNN1 | calponin 1, basic, smooth muscle |
| CROT | carnitine O-octanoyltransferase |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DUSP26 | dual specificity phosphatase 26 (putative) |
| DUSP4 | dual specificity phosphatase 4 |
| ECE1 | endothelin converting enzyme 1 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ESR1 | estrogen receptor 1 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FN1 | fibronectin 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GLRB | glycine receptor, beta |
| GSTT1 | glutathione S-transferase theta 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HKDC1 | hexokinase domain containing 1 |
| HPX | hemopexin |
| HRH4 | histamine receptor H4 |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGL | immunoglobulin lambda locus |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KHK | ketohexokinase (fructokinase) |
| KIFC3 | kinesin family member C3 |
| LMNA | lamin A/C |
| LRRC41 | leucine rich repeat containing 41 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAOA | monoamine oxidase A |
| MID2 | midline 2 |
| MTA1 | metastasis associated 1 |
| MTMR8 | myotubularin related protein 8 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NINJ2 | ninjurin 2 |
| NPEPL1 | aminopeptidase-like 1 |
| NPTX1 | neuronal pentraxin I |
| NXN | nucleoredoxin |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PARVB | parvin, beta |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PGAP3 | post-GPI attachment to proteins 3 |
| PML | promyelocytic leukemia |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PRDX2 | peroxiredoxin 2 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RASAL2 | RAS protein activator like 2 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| S100A1 | S100 calcium binding protein A1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SFN | stratifin |
| SH3PXD2A | SH3 and PX domains 2A |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPRR2B | small proline-rich protein 2B |
| SSTR4 | somatostatin receptor 4 |
| SYNGR3 | synaptogyrin 3 |
| TAOK2 | TAO kinase 2 |
| TAPBP | TAP binding protein (tapasin) |
| TEX40 | testis expressed 40 |
| TMOD1 | tropomodulin 1 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TRA | T cell receptor alpha locus |
| TRIM3 | tripartite motif containing 3 |
| TSC2 | tuberous sclerosis 2 |
| TTC9 | tetratricopeptide repeat domain 9 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| XAB2 | XPA binding protein 2 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF202 | zinc finger protein 202 |
| ZNF768 | zinc finger protein 768 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| AKTIP | AKT interacting protein |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC91 | coiled-coil domain containing 91 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD180 | CD180 molecule |
| CD69 | CD69 molecule |
| CISH | cytokine inducible SH2-containing protein |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EDC3 | enhancer of mRNA decapping 3 |
| EGR2 | early growth response 2 |
| ELAC1 | elaC ribonuclease Z 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FER | fer (fps/fes related) tyrosine kinase |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GID4 | GID complex subunit 4 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPATCH2 | G patch domain containing 2 |
| GPR85 | G protein-coupled receptor 85 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H2BI | histone cluster 1, H2bi |
| HOXA1 | homeobox A1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRF8 | interferon regulatory factor 8 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIF1B | kinesin family member 1B |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAK | male germ cell-associated kinase |
| MAP3K7CL | MAP3K7 C-terminal like |
| MCPH1 | microcephalin 1 |
| MDM4 | MDM4, p53 regulator |
| MIR22HG | MIR22 host gene |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MYO1E | myosin IE |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PDZD7 | PDZ domain containing 7 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PLA2G12A | phospholipase A2, group XIIA |
| PMCH | pro-melanin-concentrating hormone |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PSKH1 | protein serine kinase H1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB17 | RAB17, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS13 | regulator of G-protein signaling 13 |
| RRAGB | Ras-related GTP binding B |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SECISBP2 | SECIS binding protein 2 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SMAD7 | SMAD family member 7 |
| SNX16 | sorting nexin 16 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPRYD7 | SPRY domain containing 7 |
| STAG3 | stromal antigen 3 |
| STAP1 | signal transducing adaptor family member 1 |
| STRN | striatin, calmodulin binding protein |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| THAP10 | THAP domain containing 10 |
| TLR4 | toll-like receptor 4 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRABD | TraB domain containing |
| UPP1 | uridine phosphorylase 1 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| XYLT2 | xylosyltransferase II |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF155 | zinc finger protein 155 |
| ZNF250 | zinc finger protein 250 |
| ZNF280D | zinc finger protein 280D |
| ZNF480 | zinc finger protein 480 |
| ZNF529 | zinc finger protein 529 |
| ZNF552 | zinc finger protein 552 |
| ZNF667 | zinc finger protein 667 |
| ZNF770 | zinc finger protein 770 |
