| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the memantine-4017 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADCY9 | adenylate cyclase 9 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APOE | apolipoprotein E |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BAGE | B melanoma antigen |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| BEND5 | BEN domain containing 5 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACFD1 | calcium channel flower domain containing 1 |
| CALCR | calcitonin receptor |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC186 | coiled-coil domain containing 186 |
| CDC42 | cell division cycle 42 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CENPJ | centromere protein J |
| CHM | choroideremia (Rab escort protein 1) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CNTFR | ciliary neurotrophic factor receptor |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CST4 | cystatin S |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOCK10 | dedicator of cytokinesis 10 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| E2F1 | E2F transcription factor 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPHA5 | EPH receptor A5 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FRY | furry homolog (Drosophila) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GP6 | glycoprotein VI (platelet) |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| IL12A | interleukin 12A |
| IL18R1 | interleukin 18 receptor 1 |
| IL6 | interleukin 6 |
| IRX4 | iroquois homeobox 4 |
| LMX1B | LIM homeobox transcription factor 1, beta |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MEF2D | myocyte enhancer factor 2D |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| NNMT | nicotinamide N-methyltransferase |
| PAPOLG | poly(A) polymerase gamma |
| PAX4 | paired box 4 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PLCD1 | phospholipase C, delta 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRKCE | protein kinase C, epsilon |
| PRKCI | protein kinase C, iota |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RABGAP1 | RAB GTPase activating protein 1 |
| RASAL2 | RAS protein activator like 2 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RGS12 | regulator of G-protein signaling 12 |
| RGS5 | regulator of G-protein signaling 5 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| RXRB | retinoid X receptor, beta |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEC24A | SEC24 family member A |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SYCP2 | synaptonemal complex protein 2 |
| TGFA | transforming growth factor, alpha |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TOP3B | topoisomerase (DNA) III beta |
| TPM3 | tropomyosin 3 |
| TPP1 | tripeptidyl peptidase I |
| TTC30A | tetratricopeptide repeat domain 30A |
| UPB1 | ureidopropionase, beta |
| WNK1 | WNK lysine deficient protein kinase 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZNF155 | zinc finger protein 155 |
| ZNF24 | zinc finger protein 24 |
| ZNF473 | zinc finger protein 473 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B9D2 | B9 protein domain 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CABIN1 | calcineurin binding protein 1 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CHI3L2 | chitinase 3-like 2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRLF1 | cytokine receptor-like factor 1 |
| CYB5R2 | cytochrome b5 reductase 2 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DLL3 | delta-like 3 (Drosophila) |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPN1 | epsin 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF3 | fibroblast growth factor 3 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAS8 | growth arrest-specific 8 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR21 | G protein-coupled receptor 21 |
| GPR85 | G protein-coupled receptor 85 |
| GRAMD1C | GRAM domain containing 1C |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRM4 | glutamate receptor, metabotropic 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2 | interleukin 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| LAMC3 | laminin, gamma 3 |
| LATS1 | large tumor suppressor kinase 1 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MMP3 | matrix metallopeptidase 3 |
| MNMIP1 | manchette microtubule inner protein 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PICK1 | protein interacting with PRKCA 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POLL | polymerase (DNA directed), lambda |
| POM121 | POM121 transmembrane nucleoporin |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCG2 | secretogranin II |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLAMF7 | SLAM family member 7 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| STAB2 | stabilin 2 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TPCN1 | two pore segment channel 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VGLL3 | vestigial-like family member 3 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF276 | zinc finger protein 276 |
| ZNF528 | zinc finger protein 528 |
| ZNF747 | zinc finger protein 747 |
