| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the memantine-4135 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADRA1A | adrenoceptor alpha 1A |
| AGFG2 | ArfGAP with FG repeats 2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| BRD7P3 | bromodomain containing 7 pseudogene 3 |
| BTNL3 | butyrophilin-like 3 |
| CADM3 | cell adhesion molecule 3 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD58 | CD58 molecule |
| CD93 | CD93 molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLDN11 | claudin 11 |
| CLEC4E | C-type lectin domain family 4, member E |
| COL1A1 | collagen, type I, alpha 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYTH1 | cytohesin 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DOCK6 | dedicator of cytokinesis 6 |
| DUSP1 | dual specificity phosphatase 1 |
| EDA | ectodysplasin A |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EMC1 | ER membrane protein complex subunit 1 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FBXO2 | F-box protein 2 |
| FCAR | Fc fragment of IgA receptor |
| FLOT1 | flotillin 1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FST | follistatin |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAB1 | GRB2-associated binding protein 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HOXA2 | homeobox A2 |
| HPX | hemopexin |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| LOC647070 | uncharacterized LOC647070 |
| LOC729164 | hCG1732469 |
| MAL | mal, T-cell differentiation protein |
| MED25 | mediator complex subunit 25 |
| MEFV | Mediterranean fever |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MID1 | midline 1 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MIP | major intrinsic protein of lens fiber |
| MUC3B | mucin 3B, cell surface associated |
| MYH14 | myosin, heavy chain 14, non-muscle |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| ODAM | odontogenic, ameloblast asssociated |
| OPRM1 | opioid receptor, mu 1 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRMT2IP | PRMT2 interacting protein |
| PTAFR | platelet-activating factor receptor |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RANBP1 | RAN binding protein 1 |
| RANBP3 | RAN binding protein 3 |
| RGS10 | regulator of G-protein signaling 10 |
| SCARF1 | scavenger receptor class F, member 1 |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC35E2 | solute carrier family 35, member E2 |
| SNX29 | sorting nexin 29 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| SSPN | sarcospan |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUGP1 | SURP and G patch domain containing 1 |
| THBS2 | thrombospondin 2 |
| THY1 | Thy-1 cell surface antigen |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TOP3B | topoisomerase (DNA) III beta |
| TP73-AS1 | TP73 antisense RNA 1 |
| TUBA4B | tubulin, alpha 4b |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDR55 | WD repeat domain 55 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A2M | alpha-2-macroglobulin |
| ADCY7 | adenylate cyclase 7 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| CDK6 | cyclin-dependent kinase 6 |
| CEP131 | centrosomal protein 131kDa |
| CFHR4 | complement factor H-related 4 |
| CLCA1 | chloride channel accessory 1 |
| CLSTN2 | calsyntenin 2 |
| CNTNAP1 | contactin associated protein 1 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CSF1R | colony stimulating factor 1 receptor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNM3 | dynamin 3 |
| DOK5 | docking protein 5 |
| EFNA3 | ephrin-A3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM169A | family with sequence similarity 169, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXO31 | F-box protein 31 |
| FLCN | folliculin |
| FRK | fyn-related Src family tyrosine kinase |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPATCH2L | G patch domain containing 2-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HDAC11 | histone deacetylase 11 |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLHL25 | kelch-like family member 25 |
| KRT83 | keratin 83, type II |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MED15 | mediator complex subunit 15 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MVP | major vault protein |
| NELL2 | NEL-like 2 (chicken) |
| NIPAL2 | NIPA-like domain containing 2 |
| NME5 | NME/NM23 family member 5 |
| NPY4R | neuropeptide Y receptor Y4 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PDE8B | phosphodiesterase 8B |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| POPDC3 | popeye domain containing 3 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB3D | RAB3D, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RECQL4 | RecQ protein-like 4 |
| RIN2 | Ras and Rab interactor 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SNTA1 | syntrophin, alpha 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEP1 | telomerase-associated protein 1 |
| TIPRL | TOR signaling pathway regulator |
| TMEM53 | transmembrane protein 53 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM16 | tripartite motif containing 16 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| UCN | urocortin |
| UPK2 | uroplakin 2 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VASH2 | vasohibin 2 |
| WDR4 | WD repeat domain 4 |
| WDR76 | WD repeat domain 76 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF230 | zinc finger protein 230 |
| ZNF324 | zinc finger protein 324 |
| ZNF652 | zinc finger protein 652 |
