| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the memantine-7354 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADCK2 | aarF domain containing kinase 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| CA4 | carbonic anhydrase IV |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD4 | CD4 molecule |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DPYS | dihydropyrimidinase |
| DSPP | dentin sialophosphoprotein |
| DVL2 | dishevelled segment polarity protein 2 |
| EMC3 | ER membrane protein complex subunit 3 |
| EXO5 | exonuclease 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FLJ11292 | |
| FRMD4B | FERM domain containing 4B |
| GATA4 | GATA binding protein 4 |
| GPR137 | G protein-coupled receptor 137 |
| GPR3 | G protein-coupled receptor 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GTPBP4 | GTP binding protein 4 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H2BL | histone cluster 1, H2bl |
| HIST1H2BN | histone cluster 1, H2bn |
| HLA-C | major histocompatibility complex, class I, C |
| HOXC8 | homeobox C8 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL1B | interleukin 1, beta |
| IL1RN | interleukin 1 receptor antagonist |
| IL6ST | interleukin 6 signal transducer |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLF9 | Kruppel-like factor 9 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAX | MYC associated factor X |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFAP3L | microfibrillar-associated protein 3-like |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCOR2 | nuclear receptor corepressor 2 |
| NF1 | neurofibromin 1 |
| NKX2-1 | NK2 homeobox 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NRF1 | nuclear respiratory factor 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE12 | phosphodiesterase 12 |
| PER3 | period circadian clock 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLIN2 | perilipin 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRSS53 | protease, serine, 53 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB11B | RAB11B, member RAS oncogene family |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RGS12 | regulator of G-protein signaling 12 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SFTPB | surfactant protein B |
| SIX2 | SIX homeobox 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| ST5 | suppression of tumorigenicity 5 |
| STMN1 | stathmin 1 |
| TADA3 | transcriptional adaptor 3 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMEM63A | transmembrane protein 63A |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TOP3B | topoisomerase (DNA) III beta |
| TREX1 | three prime repair exonuclease 1 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| TROVE2 | TROVE domain family, member 2 |
| TTBK2 | tau tubulin kinase 2 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| USP22 | ubiquitin specific peptidase 22 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF222 | zinc finger protein 222 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ATG2A | autophagy related 2A |
| BAK1 | BCL2-antagonist/killer 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L2 | BCL2-like 2 |
| BMP4 | bone morphogenetic protein 4 |
| CARD8 | caspase recruitment domain family, member 8 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIC | capicua transcriptional repressor |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN15 | claudin 15 |
| CLSTN2 | calsyntenin 2 |
| CRBN | cereblon |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EPHA2 | EPH receptor A2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FMO4 | flavin containing monooxygenase 4 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLI3 | GLI family zinc finger 3 |
| GPC3 | glypican 3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| H2AFY2 | H2A histone family, member Y2 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF9 | interferon regulatory factor 9 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JMJD4 | jumonji domain containing 4 |
| KIF13B | kinesin family member 13B |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL12 | kelch-like family member 12 |
| LAMB3 | laminin, beta 3 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MKS1 | Meckel syndrome, type 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| ONECUT2 | one cut homeobox 2 |
| OSMR | oncostatin M receptor |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCDHB13 | protocadherin beta 13 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| SALL2 | spalt-like transcription factor 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SP1 | Sp1 transcription factor |
| SPAG7 | sperm associated antigen 7 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| THBS3 | thrombospondin 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM209 | transmembrane protein 209 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TWF2 | twinfilin actin binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| VIM | vimentin |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| ZNF227 | zinc finger protein 227 |
| ZNF365 | zinc finger protein 365 |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZNF492 | zinc finger protein 492 |
| ZNF506 | zinc finger protein 506 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
