| Dataset | GO Cellular Component Annotations 2025 |
| Category | structural or functional annotations |
| Type | cellular component |
| Description | A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. (Gene Ontology, GO_0005579) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0005579 |
| Similar Terms | |
| Downloads & Tools |
7 proteins localized to the membrane attack complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| C5 | complement component 5 |
| C8A | complement component 8, alpha polypeptide |
| C8B | complement component 8, beta polypeptide |
| C8G | complement component 8, gamma polypeptide |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 |
