membrane protein ectodomain proteolysis Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). (Gene Ontology, GO_0006509)
External Link http://amigo.geneontology.org/amigo/term/GO:0006509
Similar Terms
Downloads & Tools

Genes

23 genes participating in the membrane protein ectodomain proteolysis biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM19 ADAM metallopeptidase domain 19
ADAM9 ADAM metallopeptidase domain 9
APH1A APH1A gamma secretase subunit
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
ERAP1 endoplasmic reticulum aminopeptidase 1
HM13 histocompatibility (minor) 13
MMP7 matrix metallopeptidase 7
MYH9 myosin, heavy chain 9, non-muscle
NCSTN nicastrin
PRKCQ protein kinase C, theta
PRTN3 proteinase 3
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
RBMX RNA binding motif protein, X-linked
SPPL2A signal peptide peptidase like 2A
SPPL2B signal peptide peptidase like 2B
SPPL2C signal peptide peptidase like 2C
SPPL3 signal peptide peptidase like 3