membrane protein intracellular domain proteolysis Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. (Gene Ontology, GO_0031293)
External Link http://amigo.geneontology.org/amigo/term/GO:0031293
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Genes

14 genes participating in the membrane protein intracellular domain proteolysis biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM9 ADAM metallopeptidase domain 9
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
HM13 histocompatibility (minor) 13
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MMP7 matrix metallopeptidase 7
NCSTN nicastrin
PSENEN presenilin enhancer gamma secretase subunit
RHBDD1 rhomboid domain containing 1
SPPL2A signal peptide peptidase like 2A
SPPL2B signal peptide peptidase like 2B
SPPL2C signal peptide peptidase like 2C
TGFB1 transforming growth factor, beta 1