membrane raft Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. (Gene Ontology, GO_0045121)
External Link http://amigo.geneontology.org/amigo/term/GO:0045121
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Genes

170 proteins localized to the membrane raft cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE2 angiotensin I converting enzyme 2
ADAM17 ADAM metallopeptidase domain 17
ADCY2 adenylate cyclase 2 (brain)
ADCY8 adenylate cyclase 8 (brain)
ADD2 adducin 2 (beta)
AHNAK AHNAK nucleoprotein
AKAP5 A kinase (PRKA) anchor protein 5
ANGPT1 angiopoietin 1
ANXA2 annexin A2
APP amyloid beta (A4) precursor protein
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BTK Bruton agammaglobulinemia tyrosine kinase
C1ORF168 chromosome 1 open reading frame 168
CAPN2 calpain 2, (m/II) large subunit
CARD11 caspase recruitment domain family, member 11
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CAV3 caveolin 3
CAVIN1 caveolae associated protein 1
CAVIN2 caveolae associated protein 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CD14 CD14 molecule
CD177 CD177 molecule
CD226 CD226 molecule
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD4 CD4 molecule
CD48 CD48 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD79A CD79a molecule, immunoglobulin-associated alpha
CD8A CD8a molecule
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLIP3 CAP-GLY domain containing linker protein 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTSD cathepsin D
CXADR coxsackie virus and adenovirus receptor
DLL1 delta-like 1 (Drosophila)
DMD dystrophin
DYNLL1 dynein, light chain, LC8-type 1
EGFR epidermal growth factor receptor
EMP2 epithelial membrane protein 2
ERLIN1 ER lipid raft associated 1
ERLIN2 ER lipid raft associated 2
EZR ezrin
FAIM2 Fas apoptotic inhibitory molecule 2
FAM102A family with sequence similarity 102, member A
FAS Fas cell surface death receptor
FLOT1 flotillin 1
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GHSR growth hormone secretagogue receptor
GJA1 gap junction protein, alpha 1, 43kDa
GP6 glycoprotein VI (platelet)
GPC1 glypican 1
GPM6B glycoprotein M6B
HYAL2 hyaluronoglucosaminidase 2
IL6ST interleukin 6 signal transducer
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITLN1 intelectin 1 (galactofuranose binding)
JAK2 Janus kinase 2
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDHB lactate dehydrogenase B
LRP4 low density lipoprotein receptor-related protein 4
LYN LYN proto-oncogene, Src family tyrosine kinase
LYPD4 LY6/PLAUR domain containing 4
MAL mal, T-cell differentiation protein
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MALL mal, T-cell differentiation protein-like
MAPT microtubule-associated protein tau
MFAP3 microfibrillar-associated protein 3
MME membrane metallo-endopeptidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MYADM myeloid-associated differentiation marker
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYO1C myosin IC
NFAM1 NFAT activating protein with ITAM motif 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS1 nitric oxide synthase 1 (neuronal)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NTSR1 neurotensin receptor 1 (high affinity)
ORAI1 ORAI calcium release-activated calcium modulator 1
ORC3 origin recognition complex, subunit 3
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PDPN podoplanin
PGK1 phosphoglycerate kinase 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLPP3 phospholipid phosphatase 3
PLSCR1 phospholipid scramblase 1
PPAP2A phosphatidic acid phosphatase type 2A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPT1 palmitoyl-protein thioesterase 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRNP prion protein
PROM2 prominin 2
PRTN3 proteinase 3
PSEN1 presenilin 1
PSEN2 presenilin 2
PTPRC protein tyrosine phosphatase, receptor type, C
RAP1B RAP1B, member of RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RIT2 Ras-like without CAAX 2
RTN4R reticulon 4 receptor
RTN4RL2 reticulon 4 receptor-like 2
S100A10 S100 calcium binding protein A10
SDCBP syndecan binding protein (syntenin)
SELE selectin E
SELPLG selectin P ligand
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SHH sonic hedgehog
SKAP1 src kinase associated phosphoprotein 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SORBS1 sorbin and SH3 domain containing 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STIM1 stromal interaction molecule 1
STOM stomatin
STOML2 stomatin (EPB72)-like 2
STX12 syntaxin 12
SULF1 sulfatase 1
TDGF1 teratocarcinoma-derived growth factor 1
TEK TEK tyrosine kinase, endothelial
TEX101 testis expressed 101
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THY1 Thy-1 cell surface antigen
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR6 toll-like receptor 6
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TPP1 tripeptidyl peptidase I
TREM2 triggering receptor expressed on myeloid cells 2
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa