menadione-2439 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the menadione-2439 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
ARC activity-regulated cytoskeleton-associated protein
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BIRC3 baculoviral IAP repeat containing 3
BTG2 BTG family, member 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CREM cAMP responsive element modulator
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EGR4 early growth response 4
EIF5 eukaryotic translation initiation factor 5
FADS3 fatty acid desaturase 3
FAM46C family with sequence similarity 46, member C
FCMR Fc fragment of IgM receptor
FKBP4 FK506 binding protein 4, 59kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45B growth arrest and DNA-damage-inducible, beta
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
GNAS GNAS complex locus
HES1 hes family bHLH transcription factor 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H2AE histone cluster 1, H2ae
HIST1H2AL histone cluster 1, H2al
HIST1H2AM histone cluster 1, H2am
HIST1H2BG histone cluster 1, H2bg
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICAM1 intercellular adhesion molecule 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDI2-AS1 IDI2 antisense RNA 1
IER3 immediate early response 3
IER5 immediate early response 5
IFI30 interferon, gamma-inducible protein 30
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL24 interleukin 24
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KYNU kynureninase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MMP19 matrix metallopeptidase 19
MTUS1 microtubule associated tumor suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOV nephroblastoma overexpressed
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PCDH9 protocadherin 9
PHLDA1 pleckstrin homology-like domain, family A, member 1
POPDC3 popeye domain containing 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHOB ras homolog family member B
RIT1 Ras-like without CAAX 1
RPL13P5 ribosomal protein L13 pseudogene 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX4 SRY (sex determining region Y)-box 4
SQSTM1 sequestosome 1
STON1 stonin 1
THBS1 thrombospondin 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIM25 tripartite motif containing 25
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ADORA3 adenosine A3 receptor
ASB13 ankyrin repeat and SOCS box containing 13
BACE1 beta-site APP-cleaving enzyme 1
BAHCC1 BAH domain and coiled-coil containing 1
BARD1 BRCA1 associated RING domain 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF49 chromosome 11 open reading frame 49
C14ORF159 chromosome 14 open reading frame 159
C16ORF59 chromosome 16 open reading frame 59
C1ORF109 chromosome 1 open reading frame 109
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR4 carbonyl reductase 4
CDC7 cell division cycle 7
CLGN calmegin
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CORO7 coronin 7
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
DDHD2 DDHD domain containing 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DPY19L2P2 DPY19L2 pseudogene 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHB6 EPH receptor B6
ETAA1 Ewing tumor-associated antigen 1
FANCC Fanconi anemia, complementation group C
FANCF Fanconi anemia, complementation group F
FLT3 fms-related tyrosine kinase 3
GINS2 GINS complex subunit 2 (Psf2 homolog)
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPHN gephyrin
GPR19 G protein-coupled receptor 19
GPR65 G protein-coupled receptor 65
HELLS helicase, lymphoid-specific
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HILPDA hypoxia inducible lipid droplet-associated
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HK2 hexokinase 2
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IMPACT impact RWD domain protein
JADE1 jade family PHD finger 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIF21B kinesin family member 21B
KIF4A kinesin family member 4A
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIG1 ligase I, DNA, ATP-dependent
LINC00341 long intergenic non-protein coding RNA 341
LRRK1 leucine-rich repeat kinase 1
LY75 lymphocyte antigen 75
MAK16 MAK16 homolog (S. cerevisiae)
MANSC1 MANSC domain containing 1
MCM3 minichromosome maintenance complex component 3
METTL8 methyltransferase like 8
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NARFL nuclear prelamin A recognition factor-like
NHLRC2 NHL repeat containing 2
NIPAL2 NIPA-like domain containing 2
NLRX1 NLR family member X1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARN poly(A)-specific ribonuclease
PBK PDZ binding kinase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
POGK pogo transposable element with KRAB domain
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
RBL1 retinoblastoma-like 1
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RPIA ribose 5-phosphate isomerase A
RPP25 ribonuclease P/MRP 25kDa subunit
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SIDT1 SID1 transmembrane family, member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLITRK5 SLIT and NTRK-like family, member 5
SOX12 SRY (sex determining region Y)-box 12
TASP1 taspase, threonine aspartase, 1
TET3 tet methylcytosine dioxygenase 3
THEM6 thioesterase superfamily member 6
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TMEM254 transmembrane protein 254
TRIM66 tripartite motif containing 66
TTC13 tetratricopeptide repeat domain 13
TTLL1 tubulin tyrosine ligase-like family member 1
UNG uracil-DNA glycosylase
WDR43 WD repeat domain 43
WDR62 WD repeat domain 62
WDR7 WD repeat domain 7
ZNF512B zinc finger protein 512B
ZNF529 zinc finger protein 529
ZNF696 zinc finger protein 696