meningitis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Meningitis is a nervous system infectious disease characterized as an inflammation of the pia-arachnoid meninges. It can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells. Meningitis is a diffuse infection caused by a variety of different agents. (Human Disease Ontology, DOID_9471)
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Genes

60 genes co-occuring with the biological term meningitis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AADAT aminoadipate aminotransferase
ADA adenosine deaminase
ADRB2 adrenoceptor beta 2, surface
ALOX5 arachidonate 5-lipoxygenase
AQP4 aquaporin 4
ARRB2 arrestin, beta 2
B2M beta-2-microglobulin
C3 complement component 3
C5 complement component 5
CARD8 caspase recruitment domain family, member 8
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
EZR ezrin
FAIM2 Fas apoptotic inhibitory molecule 2
FN1 fibronectin 1
GBP1 guanylate binding protein 1, interferon-inducible
GLCCI1 glucocorticoid induced 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL10 interleukin 10
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
LCN2 lipocalin 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MDK midkine (neurite growth-promoting factor 2)
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
NLRP1 NLR family, pyrin domain containing 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
PLAU plasminogen activator, urokinase
PRKCA protein kinase C, alpha
PTK2 protein tyrosine kinase 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
VEGFA vascular endothelial growth factor A
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta