menopause Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age. (Experimental Factor Ontology, EFO_0003922)
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Genes

44 genes associated with the disease menopause in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADGRA2 adhesion G protein-coupled receptor A2
AGBL1 ATP/GTP binding protein-like 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALOX12 arachidonate 12-lipoxygenase
APOE apolipoprotein E
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BANP BTG3 associated nuclear protein
BRSK1 BR serine/threonine kinase 1
COMT catechol-O-methyltransferase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EXO1 exonuclease 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FNDC4 fibronectin type III domain containing 4
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HELQ helicase, POLQ-like
KPNA3 karyopherin alpha 3 (importin alpha 4)
LRRN4 leucine rich repeat neuronal 4
MCM8 minichromosome maintenance complex component 8
NLRP11 NLR family, pyrin domain containing 11
NOS3 nitric oxide synthase 3 (endothelial cell)
POLG polymerase (DNA directed), gamma
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRRC2A proline-rich coiled-coil 2A
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RNF44 ring finger protein 44
SARDH sarcosine dehydrogenase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC35F3 solute carrier family 35, member F3
SLC44A4 solute carrier family 44, member 4
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SYCP2L synaptonemal complex protein 2-like
TDRD3 tudor domain containing 3
THSD4 thrombospondin, type I, domain containing 4
TLK1 tousled-like kinase 1
TMEM150B transmembrane protein 150B
UIMC1 ubiquitin interaction motif containing 1