mephenesin-2304 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the mephenesin-2304 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AKAP7 A kinase (PRKA) anchor protein 7
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPTL2 angiopoietin-like 2
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOC4 apolipoprotein C-IV
ARG1 arginase 1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF6B activating transcription factor 6 beta
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BCL6 B-cell CLL/lymphoma 6
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C19ORF66 chromosome 19 open reading frame 66
CA5B carbonic anhydrase VB, mitochondrial
CADM3 cell adhesion molecule 3
CAV3 caveolin 3
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CDC42 cell division cycle 42
CFAP69 cilia and flagella associated protein 69
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLIP2 CAP-GLY domain containing linker protein 2
CNPY4 canopy FGF signaling regulator 4
CNR2 cannabinoid receptor 2 (macrophage)
CRYGD crystallin, gamma D
CUZD1 CUB and zona pellucida-like domains 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
ELL elongation factor RNA polymerase II
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB2 EPH receptor B2
EPS8L3 EPS8-like 3
ETV7 ets variant 7
FLJ11292
GJD2 gap junction protein, delta 2, 36kDa
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPNMB glycoprotein (transmembrane) nmb
GPR25 G protein-coupled receptor 25
GREB1 growth regulation by estrogen in breast cancer 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRK5 G protein-coupled receptor kinase 5
HLA-DOA major histocompatibility complex, class II, DO alpha
HNF4A hepatocyte nuclear factor 4, alpha
IFNA14 interferon, alpha 14
INE1 inactivation escape 1 (non-protein coding)
JAM3 junctional adhesion molecule 3
KLHL20 kelch-like family member 20
KRT24 keratin 24, type I
KRT5 keratin 5, type II
LMAN1 lectin, mannose-binding, 1
MAGOH2P mago-nashi homolog 2, pseudogene
MOGAT2 monoacylglycerol O-acyltransferase 2
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYT1 myelin transcription factor 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NRG2 neuregulin 2
NRN1 neuritin 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PARD6B par-6 family cell polarity regulator beta
PDLIM4 PDZ and LIM domain 4
PIGR polymeric immunoglobulin receptor
PLCE1 phospholipase C, epsilon 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PYHIN1 pyrin and HIN domain family, member 1
RBP3 retinol binding protein 3, interstitial
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
RTEL1 regulator of telomere elongation helicase 1
S100A9 S100 calcium binding protein A9
SIRT4 sirtuin 4
SKIL SKI-like proto-oncogene
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNPH syntaphilin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRPK2 SRSF protein kinase 2
STAC SH3 and cysteine rich domain
STEAP1 six transmembrane epithelial antigen of the prostate 1
STON1 stonin 1
STYK1 serine/threonine/tyrosine kinase 1
TBC1D2 TBC1 domain family, member 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
TM4SF1 transmembrane 4 L six family member 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRA T cell receptor alpha locus
TTC38 tetratricopeptide repeat domain 38
WDR62 WD repeat domain 62
WISP1 WNT1 inducible signaling pathway protein 1
ZBTB7A zinc finger and BTB domain containing 7A
ZKSCAN7 zinc finger with KRAB and SCAN domains 7
ZNF222 zinc finger protein 222
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
BCL9 B-cell CLL/lymphoma 9
C11ORF80 chromosome 11 open reading frame 80
C21ORF91 chromosome 21 open reading frame 91
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CASZ1 castor zinc finger 1
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CD83 CD83 molecule
CEP97 centrosomal protein 97kDa
CGA glycoprotein hormones, alpha polypeptide
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNGB3 cyclic nucleotide gated channel beta 3
COBL cordon-bleu WH2 repeat protein
CPTP ceramide-1-phosphate transfer protein
CRY2 cryptochrome circadian clock 2
CUL9 cullin 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DDIT3 DNA-damage-inducible transcript 3
DEPTOR DEP domain containing MTOR-interacting protein
DUSP13 dual specificity phosphatase 13
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHX2 epoxide hydrolase 2, cytoplasmic
EXD3 exonuclease 3'-5' domain containing 3
FOXI1 forkhead box I1
GAMT guanidinoacetate N-methyltransferase
GLI3 GLI family zinc finger 3
GPATCH3 G patch domain containing 3
GPR21 G protein-coupled receptor 21
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4D histone cluster 1, H4d
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFT140 intraflagellar transport 140
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
LAMA5 laminin, alpha 5
LOC257152 uncharacterized LOC257152
LRP2 low density lipoprotein receptor-related protein 2
MAGEB2 melanoma antigen family B2
MANBA mannosidase, beta A, lysosomal
MCOLN1 mucolipin 1
MTERF4 mitochondrial transcription termination factor 4
NES nestin
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
NRSN2 neurensin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PALM paralemmin
PER3 period circadian clock 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRF1 perforin 1 (pore forming protein)
PROS1 protein S (alpha)
PTPRS protein tyrosine phosphatase, receptor type, S
PTPRU protein tyrosine phosphatase, receptor type, U
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB5B RAB5B, member RAS oncogene family
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGR retinitis pigmentosa GTPase regulator
SETD1A SET domain containing 1A
SIK1 salt-inducible kinase 1
SLC35F5 solute carrier family 35, member F5
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SPINK4 serine peptidase inhibitor, Kazal type 4
ST5 suppression of tumorigenicity 5
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D17 TBC1 domain family, member 17
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TET3 tet methylcytosine dioxygenase 3
TEX40 testis expressed 40
TFF2 trefoil factor 2
THAP1 THAP domain containing, apoptosis associated protein 1
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC33 tetratricopeptide repeat domain 33
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
WBP2 WW domain binding protein 2
XK X-linked Kx blood group
ZNF250 zinc finger protein 250
ZNF571 zinc finger protein 571
ZNF573 zinc finger protein 573
ZNF787 zinc finger protein 787
ZNRD1-AS1 ZNRD1 antisense RNA 1