| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the mephenesin-3675 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ALX4 | ALX homeobox 4 |
| ANXA10 | annexin A10 |
| ARMC4 | armadillo repeat containing 4 |
| ARSA | arylsulfatase A |
| BMP2 | bone morphogenetic protein 2 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC57 | coiled-coil domain containing 57 |
| CD5 | CD5 molecule |
| CD82 | CD82 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CXXC4 | CXXC finger protein 4 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| FAM63A | family with sequence similarity 63, member A |
| FAM65B | family with sequence similarity 65, member B |
| FBXO21 | F-box protein 21 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPM6A | glycoprotein M6A |
| GPR182 | G protein-coupled receptor 182 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXB6 | homeobox B6 |
| HR | hair growth associated |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IGSF9B | immunoglobulin superfamily, member 9B |
| IL1RN | interleukin 1 receptor antagonist |
| INADL | InaD-like (Drosophila) |
| INHBE | inhibin, beta E |
| IRF4 | interferon regulatory factor 4 |
| IRS4 | insulin receptor substrate 4 |
| ITGA7 | integrin, alpha 7 |
| KERA | keratocan |
| KIAA0319L | KIAA0319-like |
| KLF13 | Kruppel-like factor 13 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LAT2 | linker for activation of T cells family, member 2 |
| LPA | lipoprotein, Lp(a) |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MEGF6 | multiple EGF-like-domains 6 |
| MEOX1 | mesenchyme homeobox 1 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MMP25 | matrix metallopeptidase 25 |
| MPPE1 | metallophosphoesterase 1 |
| MUC7 | mucin 7, secreted |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCLN | nicalin |
| NME5 | NME/NM23 family member 5 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NTF3 | neurotrophin 3 |
| NTNG1 | netrin G1 |
| OGFR | opioid growth factor receptor |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PCP4 | Purkinje cell protein 4 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| POU3F4 | POU class 3 homeobox 4 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDM14 | PR domain containing 14 |
| PRLR | prolactin receptor |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBBP9 | retinoblastoma binding protein 9 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| RUNX1 | runt-related transcription factor 1 |
| SH2D3A | SH2 domain containing 3A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLAMF8 | SLAM family member 8 |
| SLC6A11 | solute carrier family 6 (neurotransmitter transporter), member 11 |
| SOCS7 | suppressor of cytokine signaling 7 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TAGLN3 | transgelin 3 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TBX5 | T-box 5 |
| TLX2 | T-cell leukemia homeobox 2 |
| TOP3B | topoisomerase (DNA) III beta |
| TPM3 | tropomyosin 3 |
| TUBA4B | tubulin, alpha 4b |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZFP64 | ZFP64 zinc finger protein |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ABHD8 | abhydrolase domain containing 8 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AMT | aminomethyltransferase |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1R | complement component 1, r subcomponent |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC85C | coiled-coil domain containing 85C |
| CDHR2 | cadherin-related family member 2 |
| CES3 | carboxylesterase 3 |
| CLDN11 | claudin 11 |
| CORO2A | coronin, actin binding protein, 2A |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYB5R4 | cytochrome b5 reductase 4 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ENO3 | enolase 3 (beta, muscle) |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EXOC6B | exocyst complex component 6B |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FGL1 | fibrinogen-like 1 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAN | gigaxonin |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR19 | G protein-coupled receptor 19 |
| GRPR | gastrin-releasing peptide receptor |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT81 | intraflagellar transport 81 |
| INO80D | INO80 complex subunit D |
| IQCC | IQ motif containing C |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIFC3 | kinesin family member C3 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LOC157562 | uncharacterized LOC157562 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MMP3 | matrix metallopeptidase 3 |
| MTMR12 | myotubularin related protein 12 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG4 | NDRG family member 4 |
| NEK11 | NIMA-related kinase 11 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NID2 | nidogen 2 (osteonidogen) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| OSMR | oncostatin M receptor |
| PDE12 | phosphodiesterase 12 |
| PER3 | period circadian clock 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODXL2 | podocalyxin-like 2 |
| PRR15L | proline rich 15-like |
| PRR4 | proline rich 4 (lacrimal) |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB33B | RAB33B, member RAS oncogene family |
| RASL11B | RAS-like, family 11, member B |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNF122 | ring finger protein 122 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPA4 | replication protein A4, 30kDa |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMO | smoothened, frizzled class receptor |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TFCP2L1 | transcription factor CP2-like 1 |
| TMEM180 | transmembrane protein 180 |
| TMEM212 | transmembrane protein 212 |
| TMSB15A | thymosin beta 15a |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF428 | zinc finger protein 428 |
| ZNF528 | zinc finger protein 528 |
| ZNF639 | zinc finger protein 639 |
| ZNF768 | zinc finger protein 768 |
| ZNF84 | zinc finger protein 84 |
