| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the mephenesin-4698 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| AOX1 | aldehyde oxidase 1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CALML5 | calmodulin-like 5 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CD300C | CD300c molecule |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DMXL2 | Dmx-like 2 |
| DOK4 | docking protein 4 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EMP3 | epithelial membrane protein 3 |
| EN2 | engrailed homeobox 2 |
| FAS | Fas cell surface death receptor |
| FH | fumarate hydratase |
| FRMD1 | FERM domain containing 1 |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GID4 | GID complex subunit 4 |
| GLRX3 | glutaredoxin 3 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| HBB | hemoglobin, beta |
| HIST1H4A | histone cluster 1, H4a |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDUA | iduronidase, alpha-L- |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIA3 | melanoma inhibitory activity family, member 3 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NDRG2 | NDRG family member 2 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NMT1 | N-myristoyltransferase 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| ORM1 | orosomucoid 1 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PARVA | parvin, alpha |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHA6 | protocadherin alpha 6 |
| PCNX | pecanex homolog (Drosophila) |
| PDE8B | phosphodiesterase 8B |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLAC1 | placenta-specific 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLD2 | phospholipase D2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTHLH | parathyroid hormone-like hormone |
| PTK2B | protein tyrosine kinase 2 beta |
| QKI | QKI, KH domain containing, RNA binding |
| RASAL2 | RAS protein activator like 2 |
| RECQL5 | RecQ protein-like 5 |
| RFXAP | regulatory factor X-associated protein |
| RGS12 | regulator of G-protein signaling 12 |
| RNF122 | ring finger protein 122 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPS3A | ribosomal protein S3A |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TDRKH | tudor and KH domain containing |
| TESC | tescalcin |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF304 | zinc finger protein 304 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ALPK1 | alpha-kinase 1 |
| AMT | aminomethyltransferase |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BBC3 | BCL2 binding component 3 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC69 | coiled-coil domain containing 69 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CD82 | CD82 molecule |
| CDHR2 | cadherin-related family member 2 |
| CEL | carboxyl ester lipase |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRYGC | crystallin, gamma C |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DSPP | dentin sialophosphoprotein |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM204A | family with sequence similarity 204, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGF23 | fibroblast growth factor 23 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLJ22184 | |
| GLRA1 | glycine receptor, alpha 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPC3 | glypican 3 |
| HCFC1 | host cell factor C1 |
| HCFC2 | host cell factor C2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| HOXC8 | homeobox C8 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KLF13 | Kruppel-like factor 13 |
| KLHL28 | kelch-like family member 28 |
| KRT31 | keratin 31, type I |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MUC3A | mucin 3A, cell surface associated |
| NEUROD4 | neuronal differentiation 4 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL10 | nucleolar protein 10 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAT | plasminogen activator, tissue |
| PMEL | premelanosome protein |
| POLM | polymerase (DNA directed), mu |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIN1 | Ras and Rab interactor 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| S100A9 | S100 calcium binding protein A9 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SNTA1 | syntrophin, alpha 1 |
| SP1 | Sp1 transcription factor |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STMN3 | stathmin-like 3 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCTN2 | tectonic family member 2 |
| TEAD3 | TEA domain family member 3 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRAIP | TRAF interacting protein |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3D | tubulin, alpha 3d |
| USB1 | U6 snRNA biogenesis 1 |
| VGF | VGF nerve growth factor inducible |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF623 | zinc finger protein 623 |
