| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the mephenesin-7374 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AHI1 | Abelson helper integration site 1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APH1B | APH1B gamma secretase subunit |
| APOC4 | apolipoprotein C-IV |
| APOF | apolipoprotein F |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| AXIN1 | axin 1 |
| BAX | BCL2-associated X protein |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCNJ | cyclin J |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP164 | centrosomal protein 164kDa |
| CFD | complement factor D (adipsin) |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| CYTH3 | cytohesin 3 |
| DENND4A | DENN/MADD domain containing 4A |
| DOPEY2 | dopey family member 2 |
| EDAR | ectodysplasin A receptor |
| EGF | epidermal growth factor |
| ELL | elongation factor RNA polymerase II |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ETV1 | ets variant 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM69A | family with sequence similarity 69, member A |
| FGFR4 | fibroblast growth factor receptor 4 |
| FNDC4 | fibronectin type III domain containing 4 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPM6B | glycoprotein M6B |
| GPR27 | G protein-coupled receptor 27 |
| HBB | hemoglobin, beta |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC4 | homeobox C4 |
| IDS | iduronate 2-sulfatase |
| IFNA6 | interferon, alpha 6 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL24 | interleukin 24 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KRT6B | keratin 6B, type II |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAP1B | microtubule-associated protein 1B |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPT | microtubule-associated protein tau |
| MED16 | mediator complex subunit 16 |
| MRAS | muscle RAS oncogene homolog |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NDRG2 | NDRG family member 2 |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PEX3 | peroxisomal biogenesis factor 3 |
| PGM5 | phosphoglucomutase 5 |
| PIP | prolactin-induced protein |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PML | promyelocytic leukemia |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB36 | RAB36, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| TBC1D2B | TBC1 domain family, member 2B |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TUBA3C | tubulin, alpha 3c |
| UBE3B | ubiquitin protein ligase E3B |
| WDR61 | WD repeat domain 61 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF155 | zinc finger protein 155 |
| ZNF428 | zinc finger protein 428 |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADCY7 | adenylate cyclase 7 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARRB2 | arrestin, beta 2 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BOLA1 | bolA family member 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CAPN15 | calpain 15 |
| CBX7 | chromobox homolog 7 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC68 | coiled-coil domain containing 68 |
| CCNE1 | cyclin E1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD70 | CD70 molecule |
| CDH7 | cadherin 7, type 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLEC10A | C-type lectin domain family 10, member A |
| CLSPN | claspin |
| CNPY3 | canopy FGF signaling regulator 3 |
| CPA4 | carboxypeptidase A4 |
| CTAGE9 | CTAGE family, member 9 |
| CTSK | cathepsin K |
| CTSV | cathepsin V |
| CUL9 | cullin 9 |
| DBR1 | debranching RNA lariats 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| FER | fer (fps/fes related) tyrosine kinase |
| FHOD1 | formin homology 2 domain containing 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GALK1 | galactokinase 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPR137B | G protein-coupled receptor 137B |
| HELZ | helicase with zinc finger |
| HIST1H2AM | histone cluster 1, H2am |
| HYI | hydroxypyruvate isomerase (putative) |
| IMPACT | impact RWD domain protein |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0753 | KIAA0753 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MANBA | mannosidase, beta A, lysosomal |
| MBD5 | methyl-CpG binding domain protein 5 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MT1M | metallothionein 1M |
| NOL12 | nucleolar protein 12 |
| NOTCH1 | notch 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUBPL | nucleotide binding protein-like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMM1 | phosphomannomutase 1 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFX7 | regulatory factor X, 7 |
| RIN1 | Ras and Rab interactor 1 |
| SETBP1 | SET binding protein 1 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPAG4 | sperm associated antigen 4 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| SYNPO | synaptopodin |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM51 | transmembrane protein 51 |
| TMEM8B | transmembrane protein 8B |
| TOR4A | torsin family 4, member A |
| TRIM26 | tripartite motif containing 26 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UGT8 | UDP glycosyltransferase 8 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| YEATS2 | YEATS domain containing 2 |
| ZNF254 | zinc finger protein 254 |
| ZNF263 | zinc finger protein 263 |
| ZNF329 | zinc finger protein 329 |
| ZNF350 | zinc finger protein 350 |
| ZNF671 | zinc finger protein 671 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 |
| ZXDC | ZXD family zinc finger C |
