mephenesin Gene Set
Genes
19 genes differentially expressed following the mephenesin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EPHB2
|
EPH receptor B2
|
5.03325
|
|
VPS35
|
vacuolar protein sorting 35 homolog (S. cerevisiae)
|
3.58705
|
|
EGF
|
epidermal growth factor
|
3.45183
|
|
ZNF587
|
zinc finger protein 587
|
3.36448
|
|
UBQLN4
|
ubiquilin 4
|
3.29304
|
|
TBP
|
TATA box binding protein
|
3.26249
|
|
DLD
|
dihydrolipoamide dehydrogenase
|
3.22648
|
|
RPL26
|
ribosomal protein L26
|
3.21457
|
|
MSRB1
|
methionine sulfoxide reductase B1
|
3.1472
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.11766
|
|
H1-6
|
H1.6 linker histone, cluster member
|
3.05082
|
|
ZNF721
|
zinc finger protein 721
|
3.03628
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NFKBIB
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
|
-5.36453
|
|
CANT1
|
calcium activated nucleotidase 1
|
-4.7515
|
|
TSPAN4
|
tetraspanin 4
|
-3.40675
|
|
APLNR
|
apelin receptor
|
-3.20521
|
|
ITGB1
|
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
|
-3.17767
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.16859
|
|
UGT8
|
UDP glycosyltransferase 8
|
-3.10344
|
