mephentermine-2563 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mephentermine-2563 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
ADAM12 ADAM metallopeptidase domain 12
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANO1 anoctamin 1, calcium activated chloride channel
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARMCX1 armadillo repeat containing, X-linked 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BIN1 bridging integrator 1
BTF3P11 basic transcription factor 3 pseudogene 11
C9ORF116 chromosome 9 open reading frame 116
CCL20 chemokine (C-C motif) ligand 20
CD160 CD160 molecule
CD52 CD52 molecule
CD59 CD59 molecule, complement regulatory protein
CD6 CD6 molecule
CD69 CD69 molecule
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLIC2 chloride intracellular channel 2
CNTFR ciliary neurotrophic factor receptor
COL14A1 collagen, type XIV, alpha 1
COL1A2 collagen, type I, alpha 2
COL7A1 collagen, type VII, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRABP2 cellular retinoic acid binding protein 2
EDN3 endothelin 3
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EMP1 epithelial membrane protein 1
ENO2 enolase 2 (gamma, neuronal)
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPAS1 endothelial PAS domain protein 1
FAM106A family with sequence similarity 106, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGL1 fibrinogen-like 1
FOXG1 forkhead box G1
FTH1 ferritin, heavy polypeptide 1
GPNMB glycoprotein (transmembrane) nmb
HIST1H4A histone cluster 1, H4a
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IQSEC1 IQ motif and Sec7 domain 1
ITGB5 integrin, beta 5
JMJD6 jumonji domain containing 6
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KLF3 Kruppel-like factor 3 (basic)
KLHL1 kelch-like family member 1
LBX1 ladybird homeobox 1
LPAR3 lysophosphatidic acid receptor 3
MCM3AP minichromosome maintenance complex component 3 associated protein
MDFI MyoD family inhibitor
MED25 mediator complex subunit 25
METTL7A methyltransferase like 7A
MIER2 mesoderm induction early response 1, family member 2
MMP19 matrix metallopeptidase 19
MRC2 mannose receptor, C type 2
MTCP1 mature T-cell proliferation 1
MX1 MX dynamin-like GTPase 1
MYBPH myosin binding protein H
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCOA2 nuclear receptor coactivator 2
NMU neuromedin U
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OSBPL10 oxysterol binding protein-like 10
PALLD palladin, cytoskeletal associated protein
PARP11 poly (ADP-ribose) polymerase family, member 11
PARP3 poly (ADP-ribose) polymerase family, member 3
PHF20L1 PHD finger protein 20-like 1
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKN2 protein kinase N2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNOC prepronociceptin
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRM2 protamine 2
RAD51B RAD51 paralog B
RGS13 regulator of G-protein signaling 13
RGS6 regulator of G-protein signaling 6
RHOH ras homolog family member H
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SGSH N-sulfoglucosamine sulfohydrolase
SHB Src homology 2 domain containing adaptor protein B
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATA20 spermatogenesis associated 20
STK24 serine/threonine kinase 24
THPO thrombopoietin
TMEM140 transmembrane protein 140
TMEM45A transmembrane protein 45A
TRO trophinin
TRPM1 transient receptor potential cation channel, subfamily M, member 1
UBOX5 U-box domain containing 5
ZBTB7B zinc finger and BTB domain containing 7B
ZC3H7B zinc finger CCCH-type containing 7B
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKTIP AKT interacting protein
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ANO10 anoctamin 10
ARRB1 arrestin, beta 1
AXIN1 axin 1
C11ORF95 chromosome 11 open reading frame 95
CCNB1 cyclin B1
CCNF cyclin F
CD320 CD320 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDC20 cell division cycle 20
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CENPA centromere protein A
CHML choroideremia-like (Rab escort protein 2)
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTSG cathepsin G
DDN dendrin
DEAF1 DEAF1 transcription factor
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOLK dolichol kinase
DPH2 DPH2 homolog (S. cerevisiae)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELAC1 elaC ribonuclease Z 1
ELP5 elongator acetyltransferase complex subunit 5
EXD2 exonuclease 3'-5' domain containing 2
FAM53B family with sequence similarity 53, member B
FBXL6 F-box and leucine-rich repeat protein 6
GCDH glutaryl-CoA dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
GMEB1 glucocorticoid modulatory element binding protein 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPHN gephyrin
GPR27 G protein-coupled receptor 27
GRAMD1B GRAM domain containing 1B
GTF2I general transcription factor IIi
HAUS7 HAUS augmin-like complex, subunit 7
HP haptoglobin
KCTD20 potassium channel tetramerization domain containing 20
KIF23 kinesin family member 23
KLF1 Kruppel-like factor 1 (erythroid)
KPTN kaptin (actin binding protein)
LAMP5 lysosomal-associated membrane protein family, member 5
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOXL3 lysyl oxidase-like 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRPL12 mitochondrial ribosomal protein L12
MRPS34 mitochondrial ribosomal protein S34
NIP7 NIP7, nucleolar pre-rRNA processing protein
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSD1 nuclear receptor binding SET domain protein 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PDCD11 programmed cell death 11
PFKM phosphofructokinase, muscle
PLA2G12A phospholipase A2, group XIIA
PPAN peter pan homolog (Drosophila)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RANGAP1 Ran GTPase activating protein 1
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RUVBL1 RuvB-like AAA ATPase 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SIDT1 SID1 transmembrane family, member 1
SIK1 salt-inducible kinase 1
SIL1 SIL1 nucleotide exchange factor
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMYD5 SMYD family member 5
SNX16 sorting nexin 16
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEC tec protein tyrosine kinase
TESK1 testis-specific kinase 1
TLR4 toll-like receptor 4
TMEM115 transmembrane protein 115
TPX2 TPX2, microtubule-associated
TTC27 tetratricopeptide repeat domain 27
TXLNG taxilin gamma
UBIAD1 UbiA prenyltransferase domain containing 1
UPK3A uroplakin 3A
USP20 ubiquitin specific peptidase 20
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF197 zinc finger protein 197
ZNF232 zinc finger protein 232
ZNF254 zinc finger protein 254
ZNF74 zinc finger protein 74
ZNHIT2 zinc finger, HIT-type containing 2