| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the mephentermine-3425 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARRB2 | arrestin, beta 2 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP9A | ATPase, class II, type 9A |
| BBS9 | Bardet-Biedl syndrome 9 |
| BMP1 | bone morphogenetic protein 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCDC88A | coiled-coil domain containing 88A |
| CD82 | CD82 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DRD1 | dopamine receptor D1 |
| DTNA | dystrobrevin, alpha |
| EDA | ectodysplasin A |
| EDAR | ectodysplasin A receptor |
| EFNB3 | ephrin-B3 |
| EGFR | epidermal growth factor receptor |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM198B | family with sequence similarity 198, member B |
| GAL | galanin/GMAP prepropeptide |
| GAMT | guanidinoacetate N-methyltransferase |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GMPR | guanosine monophosphate reductase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPATCH3 | G patch domain containing 3 |
| GPR143 | G protein-coupled receptor 143 |
| GSDMB | gasdermin B |
| GSN | gelsolin |
| H2AFX | H2A histone family, member X |
| HFE | hemochromatosis |
| HHAT | hedgehog acyltransferase |
| HR | hair growth associated |
| ICAM1 | intercellular adhesion molecule 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFNA14 | interferon, alpha 14 |
| IL1A | interleukin 1, alpha |
| INCENP | inner centromere protein antigens 135/155kDa |
| ING4 | inhibitor of growth family, member 4 |
| KAZN | kazrin, periplakin interacting protein |
| KITLG | KIT ligand |
| LAMB1 | laminin, beta 1 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC729164 | hCG1732469 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTD1 | mbt domain containing 1 |
| MTAP | methylthioadenosine phosphorylase |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NTF3 | neurotrophin 3 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLAC1 | placenta-specific 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRF1 | perforin 1 (pore forming protein) |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| PXN | paxillin |
| RECQL5 | RecQ protein-like 5 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RHEB | Ras homolog enriched in brain |
| RNF122 | ring finger protein 122 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOCS1 | suppressor of cytokine signaling 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAOK1 | TAO kinase 1 |
| TBX19 | T-box 19 |
| TDRD1 | tudor domain containing 1 |
| TESC | tescalcin |
| TK2 | thymidine kinase 2, mitochondrial |
| TLR2 | toll-like receptor 2 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSPAN1 | tetraspanin 1 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZFPL1 | zinc finger protein-like 1 |
| Symbol | Name |
|---|---|
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATG2B | autophagy related 2B |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CASD1 | CAS1 domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLSPN | claspin |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COL9A2 | collagen, type IX, alpha 2 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTSK | cathepsin K |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC5 | excision repair cross-complementation group 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM193B | family with sequence similarity 193, member B |
| FAM53B | family with sequence similarity 53, member B |
| FEM1C | fem-1 homolog c (C. elegans) |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GYS1 | glycogen synthase 1 (muscle) |
| HCFC2 | host cell factor C2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIRA | histone cell cycle regulator |
| IMPACT | impact RWD domain protein |
| KIF16B | kinesin family member 16B |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT13 | keratin 13, type I |
| LMNB2 | lamin B2 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGEH1 | melanoma antigen family H1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| NBEAL2 | neurobeachin-like 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PCDHB3 | protocadherin beta 3 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLIN3 | perilipin 3 |
| PNPO | pyridoxamine 5'-phosphate oxidase |
| PODXL | podocalyxin-like |
| PRPH | peripherin |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RIN2 | Ras and Rab interactor 2 |
| RNF2 | ring finger protein 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SH2B3 | SH2B adaptor protein 3 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIRT6 | sirtuin 6 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPATA2L | spermatogenesis associated 2-like |
| SPATA7 | spermatogenesis associated 7 |
| THBS3 | thrombospondin 3 |
| TMEM104 | transmembrane protein 104 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNRC6B | trinucleotide repeat containing 6B |
| TNS2 | tensin 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRABD | TraB domain containing |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM45 | tripartite motif containing 45 |
| TRIM5 | tripartite motif containing 5 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TSC1 | tuberous sclerosis 1 |
| TSPAN15 | tetraspanin 15 |
| TSPYL2 | TSPY-like 2 |
| USP6NL | USP6 N-terminal like |
| WDR91 | WD repeat domain 91 |
| WRN | Werner syndrome, RecQ helicase-like |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF134 | zinc finger protein 134 |
| ZNF141 | zinc finger protein 141 |
| ZNF350 | zinc finger protein 350 |
| ZNF652 | zinc finger protein 652 |