mephentermine-3425 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mephentermine-3425 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAM22 ADAM metallopeptidase domain 22
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ARL4C ADP-ribosylation factor-like 4C
ARRB2 arrestin, beta 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP9A ATPase, class II, type 9A
BBS9 Bardet-Biedl syndrome 9
BMP1 bone morphogenetic protein 1
C22ORF46 chromosome 22 open reading frame 46
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC88A coiled-coil domain containing 88A
CD82 CD82 molecule
CDRT1 CMT1A duplicated region transcript 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DRD1 dopamine receptor D1
DTNA dystrobrevin, alpha
EDA ectodysplasin A
EDAR ectodysplasin A receptor
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
EXTL3 exostosin-like glycosyltransferase 3
FAM198B family with sequence similarity 198, member B
GAL galanin/GMAP prepropeptide
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GPR143 G protein-coupled receptor 143
GSDMB gasdermin B
GSN gelsolin
H2AFX H2A histone family, member X
HFE hemochromatosis
HHAT hedgehog acyltransferase
HR hair growth associated
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IFNA14 interferon, alpha 14
IL1A interleukin 1, alpha
INCENP inner centromere protein antigens 135/155kDa
ING4 inhibitor of growth family, member 4
KAZN kazrin, periplakin interacting protein
KITLG KIT ligand
LAMB1 laminin, beta 1
LMAN1 lectin, mannose-binding, 1
LOC729164 hCG1732469
MAP2K2 mitogen-activated protein kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MTAP methylthioadenosine phosphorylase
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NTF3 neurotrophin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OASL 2'-5'-oligoadenylate synthetase-like
PDGFB platelet-derived growth factor beta polypeptide
PHEX phosphate regulating endopeptidase homolog, X-linked
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC1 placenta-specific 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRDM2 PR domain containing 2, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PXN paxillin
RECQL5 RecQ protein-like 5
REPS1 RALBP1 associated Eps domain containing 1
RHEB Ras homolog enriched in brain
RNF122 ring finger protein 122
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMC4 structural maintenance of chromosomes 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS1 suppressor of cytokine signaling 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPG20 spastic paraplegia 20 (Troyer syndrome)
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAOK1 TAO kinase 1
TBX19 T-box 19
TDRD1 tudor domain containing 1
TESC tescalcin
TK2 thymidine kinase 2, mitochondrial
TLR2 toll-like receptor 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TRA2A transformer 2 alpha homolog (Drosophila)
TSPAN1 tetraspanin 1
TTLL3 tubulin tyrosine ligase-like family member 3
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZBTB7A zinc finger and BTB domain containing 7A
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARL15 ADP-ribosylation factor-like 15
ATG2B autophagy related 2B
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BATF basic leucine zipper transcription factor, ATF-like
BPGM 2,3-bisphosphoglycerate mutase
C11ORF95 chromosome 11 open reading frame 95
C9ORF40 chromosome 9 open reading frame 40
CASD1 CAS1 domain containing 1
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CHRM3 cholinergic receptor, muscarinic 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COL9A2 collagen, type IX, alpha 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRABP1 cellular retinoic acid binding protein 1
CTSK cathepsin K
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC5 excision repair cross-complementation group 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM193B family with sequence similarity 193, member B
FAM53B family with sequence similarity 53, member B
FEM1C fem-1 homolog c (C. elegans)
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP10 FK506 binding protein 10, 65 kDa
GYS1 glycogen synthase 1 (muscle)
HCFC2 host cell factor C2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HHLA3 HERV-H LTR-associating 3
HIRA histone cell cycle regulator
IMPACT impact RWD domain protein
KIF16B kinesin family member 16B
KLF3 Kruppel-like factor 3 (basic)
KRT13 keratin 13, type I
LMNB2 lamin B2
LOC257152 uncharacterized LOC257152
LRRC8E leucine rich repeat containing 8 family, member E
LZTR1 leucine-zipper-like transcription regulator 1
MAGEH1 melanoma antigen family H1
MFSD11 major facilitator superfamily domain containing 11
NBEAL2 neurobeachin-like 2
NDRG1 N-myc downstream regulated 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFE2L3 nuclear factor, erythroid 2-like 3
ODF2 outer dense fiber of sperm tails 2
P3H1 prolyl 3-hydroxylase 1
PCDHB3 protocadherin beta 3
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLIN3 perilipin 3
PNPO pyridoxamine 5'-phosphate oxidase
PODXL podocalyxin-like
PRPH peripherin
PTTG3P pituitary tumor-transforming 3, pseudogene
RIN2 Ras and Rab interactor 2
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
RPGR retinitis pigmentosa GTPase regulator
SCML2 sex comb on midleg-like 2 (Drosophila)
SH2B3 SH2B adaptor protein 3
SHARPIN SHANK-associated RH domain interactor
SIRT6 sirtuin 6
SLC35F5 solute carrier family 35, member F5
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPATA2L spermatogenesis associated 2-like
SPATA7 spermatogenesis associated 7
THBS3 thrombospondin 3
TMEM104 transmembrane protein 104
TMOD3 tropomodulin 3 (ubiquitous)
TNRC6B trinucleotide repeat containing 6B
TNS2 tensin 2
TPST2 tyrosylprotein sulfotransferase 2
TRABD TraB domain containing
TRAPPC11 trafficking protein particle complex 11
TRAPPC13 trafficking protein particle complex 13
TRIM45 tripartite motif containing 45
TRIM5 tripartite motif containing 5
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSC1 tuberous sclerosis 1
TSPAN15 tetraspanin 15
TSPYL2 TSPY-like 2
USP6NL USP6 N-terminal like
WDR91 WD repeat domain 91
WRN Werner syndrome, RecQ helicase-like
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZBTB39 zinc finger and BTB domain containing 39
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF350 zinc finger protein 350
ZNF652 zinc finger protein 652