mephentermine-3685 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the mephentermine-3685 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AIM2 absent in melanoma 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANGPTL2 angiopoietin-like 2
ANGPTL4 angiopoietin-like 4
ANXA10 annexin A10
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CA5B carbonic anhydrase VB, mitochondrial
CADM4 cell adhesion molecule 4
CALCR calcitonin receptor
CCDC132 coiled-coil domain containing 132
CCL22 chemokine (C-C motif) ligand 22
CDC14A cell division cycle 14A
CHD9 chromodomain helicase DNA binding protein 9
CLCN7 chloride channel, voltage-sensitive 7
COLEC10 collectin sub-family member 10 (C-type lectin)
COPZ2 coatomer protein complex, subunit zeta 2
CSDC2 cold shock domain containing C2, RNA binding
CSF1 colony stimulating factor 1 (macrophage)
DNAAF1 dynein, axonemal, assembly factor 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FLT1 fms-related tyrosine kinase 1
FNDC4 fibronectin type III domain containing 4
FZD1 frizzled class receptor 1
GK glycerol kinase
GP5 glycoprotein V (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPM6A glycoprotein M6A
GSTA3 glutathione S-transferase alpha 3
HLA-DOA major histocompatibility complex, class II, DO alpha
IGF1R insulin-like growth factor 1 receptor
IGLJ3 immunoglobulin lambda joining 3
INADL InaD-like (Drosophila)
IRF4 interferon regulatory factor 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIF25 kinesin family member 25
KLF13 Kruppel-like factor 13
KLK13 kallikrein-related peptidase 13
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LBH limb bud and heart development
LOC100294391 uncharacterized LOC100294391
LOC440895 two pore channel 3 pseudogene
MCF2L MCF.2 cell line derived transforming sequence-like
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEF2D myocyte enhancer factor 2D
MEGF6 multiple EGF-like-domains 6
MOGAT2 monoacylglycerol O-acyltransferase 2
MPPE1 metallophosphoesterase 1
MST1L macrophage stimulating 1-like
MUC3B mucin 3B, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NGF nerve growth factor (beta polypeptide)
NTF3 neurotrophin 3
NTM neurotrimin
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OXCT2 3-oxoacid CoA transferase 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCBP3 poly(rC) binding protein 3
PCDHB13 protocadherin beta 13
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PSG11 pregnancy specific beta-1-glycoprotein 11
PSG6 pregnancy specific beta-1-glycoprotein 6
PTPRO protein tyrosine phosphatase, receptor type, O
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RIBC2 RIB43A domain with coiled-coils 2
RIMS3 regulating synaptic membrane exocytosis 3
RNF208 ring finger protein 208
RPL10L ribosomal protein L10-like
RUNX1 runt-related transcription factor 1
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
SARDH sarcosine dehydrogenase
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCN5A sodium channel, voltage gated, type V alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SH3PXD2A SH3 and PX domains 2A
SHOX2 short stature homeobox 2
SNCG synuclein, gamma (breast cancer-specific protein 1)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
TBCD tubulin folding cofactor D
TESC tescalcin
THRB thyroid hormone receptor, beta
TNS1 tensin 1
TRIO trio Rho guanine nucleotide exchange factor
TUBA4B tubulin, alpha 4b
WNT16 wingless-type MMTV integration site family, member 16
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZIC3 Zic family member 3
ZNF140 zinc finger protein 140
ZNF362 zinc finger protein 362
ZNF444 zinc finger protein 444
ZSCAN32 zinc finger and SCAN domain containing 32
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM15 ADAM metallopeptidase domain 15
ADGRE2 adhesion G protein-coupled receptor E2
AGMAT agmatine ureohydrolase (agmatinase)
ALPK3 alpha-kinase 3
ALPP alkaline phosphatase, placental
ANKFY1 ankyrin repeat and FYVE domain containing 1
APH1B APH1B gamma secretase subunit
APOL6 apolipoprotein L, 6
AURKC aurora kinase C
BEX4 brain expressed, X-linked 4
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF80 chromosome 17 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C1ORF56 chromosome 1 open reading frame 56
CDH7 cadherin 7, type 2
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
COBL cordon-bleu WH2 repeat protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL3 chemokine (C-X-C motif) ligand 3
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DLK2 delta-like 2 homolog (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
EIF5A2 eukaryotic translation initiation factor 5A2
ERN2 endoplasmic reticulum to nucleus signaling 2
GBP2 guanylate binding protein 2, interferon-inducible
GDE1 glycerophosphodiester phosphodiesterase 1
GJC1 gap junction protein, gamma 1, 45kDa
GK3P glycerol kinase 3 pseudogene
GPR176 G protein-coupled receptor 176
GREB1L growth regulation by estrogen in breast cancer-like
GRPR gastrin-releasing peptide receptor
GTPBP2 GTP binding protein 2
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IDI2-AS1 IDI2 antisense RNA 1
IL22 interleukin 22
IMPAD1 inositol monophosphatase domain containing 1
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1107 KIAA1107
KRT8P12 keratin 8 pseudogene 12
LPPR4 lipid phosphate phosphatase-related protein type 4
MBNL3 muscleblind-like splicing regulator 3
MED9 mediator complex subunit 9
MMP9 matrix metallopeptidase 9
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
MTA2 metastasis associated 1 family, member 2
MTMR12 myotubularin related protein 12
NBEAL2 neurobeachin-like 2
NIPAL2 NIPA-like domain containing 2
NT5C 5', 3'-nucleotidase, cytosolic
PALMD palmdelphin
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLAC1 placenta-specific 1
PLXNB3 plexin B3
PRPH peripherin
PRR15L proline rich 15-like
PSAT1 phosphoserine aminotransferase 1
RAB4B RAB4B, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM23 RNA binding motif protein 23
RNF2 ring finger protein 2
RNF31 ring finger protein 31
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAYSD1 SAYSVFN motif domain containing 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMO smoothened, frizzled class receptor
SNTG1 syntrophin, gamma 1
SPAG4 sperm associated antigen 4
SPTBN2 spectrin, beta, non-erythrocytic 2
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TESPA1 thymocyte expressed, positive selection associated 1
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TMEM212 transmembrane protein 212
TMEM230 transmembrane protein 230
TMEM8A transmembrane protein 8A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
ZNF10 zinc finger protein 10
ZNF134 zinc finger protein 134
ZNF205 zinc finger protein 205
ZNF415 zinc finger protein 415
ZNF428 zinc finger protein 428
ZNF506 zinc finger protein 506
ZNF529 zinc finger protein 529
ZNF639 zinc finger protein 639
ZNF665 zinc finger protein 665