| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the mephenytoin-3580 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABI2 | abl-interactor 2 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APOC4 | apolipoprotein C-IV |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| CACTIN | cactin, spliceosome C complex subunit |
| CCDC85B | coiled-coil domain containing 85B |
| CCDC9 | coiled-coil domain containing 9 |
| CDK19 | cyclin-dependent kinase 19 |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CHRD | chordin |
| CNPY4 | canopy FGF signaling regulator 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| COL4A1 | collagen, type IV, alpha 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EFNA3 | ephrin-A3 |
| EPS8L1 | EPS8-like 1 |
| ETV5 | ets variant 5 |
| FAM46C | family with sequence similarity 46, member C |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GK | glycerol kinase |
| GPR21 | G protein-coupled receptor 21 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HIST1H2BO | histone cluster 1, H2bo |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IBSP | integrin-binding sialoprotein |
| IQCK | IQ motif containing K |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KHSRP | KH-type splicing regulatory protein |
| LAMC2 | laminin, gamma 2 |
| LHB | luteinizing hormone beta polypeptide |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MED16 | mediator complex subunit 16 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP25 | matrix metallopeptidase 25 |
| MS4A5 | membrane-spanning 4-domains, subfamily A, member 5 |
| MYO1B | myosin IB |
| MYOF | myoferlin |
| NCLN | nicalin |
| NEUROD1 | neuronal differentiation 1 |
| NF1 | neurofibromin 1 |
| NMT1 | N-myristoyltransferase 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NREP | neuronal regeneration related protein |
| OPRL1 | opiate receptor-like 1 |
| PCDHB13 | protocadherin beta 13 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PON1 | paraoxonase 1 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| S100A8 | S100 calcium binding protein A8 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SDS | serine dehydratase |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMAD1 | SMAD family member 1 |
| SMAD3 | SMAD family member 3 |
| STK4 | serine/threonine kinase 4 |
| SYNJ2 | synaptojanin 2 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TBC1D17 | TBC1 domain family, member 17 |
| TENM4 | teneurin transmembrane protein 4 |
| THAP9 | THAP domain containing 9 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TRIM62 | tripartite motif containing 62 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TUBB1 | tubulin, beta 1 class VI |
| ULBP2 | UL16 binding protein 2 |
| ZNF493 | zinc finger protein 493 |
| ZNF609 | zinc finger protein 609 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATF3 | activating transcription factor 3 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC68 | coiled-coil domain containing 68 |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CENPJ | centromere protein J |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CST6 | cystatin E/M |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DOCK1 | dedicator of cytokinesis 1 |
| EDAR | ectodysplasin A receptor |
| EMID1 | EMI domain containing 1 |
| EPYC | epiphycan |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM184A | family with sequence similarity 184, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GAS2 | growth arrest-specific 2 |
| GLRA1 | glycine receptor, alpha 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GTF2I | general transcription factor IIi |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BI | histone cluster 1, H2bi |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IRF7 | interferon regulatory factor 7 |
| KIAA1107 | KIAA1107 |
| KLHL25 | kelch-like family member 25 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LAMA5 | laminin, alpha 5 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LHX1 | LIM homeobox 1 |
| LINS | lines homolog (Drosophila) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC157562 | uncharacterized LOC157562 |
| MAGEA6 | melanoma antigen family A6 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MEFV | Mediterranean fever |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMP2 | matrix metallopeptidase 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYO1E | myosin IE |
| N4BP3 | NEDD4 binding protein 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCALD | neurocalcin delta |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RIN2 | Ras and Rab interactor 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| S100A4 | S100 calcium binding protein A4 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMA4 | glucuronidase, beta pseudogene |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TKFC | triokinase/FMN cyclase |
| TMEM120B | transmembrane protein 120B |
| TMEM180 | transmembrane protein 180 |
| TMEM209 | transmembrane protein 209 |
| TMEM51 | transmembrane protein 51 |
| TMEM53 | transmembrane protein 53 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAIP | TRAF interacting protein |
| UBQLN4 | ubiquilin 4 |
| USP19 | ubiquitin specific peptidase 19 |
| WDR4 | WD repeat domain 4 |
| XYLT2 | xylosyltransferase II |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF276 | zinc finger protein 276 |
| ZNF286A | zinc finger protein 286A |
