| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the mephenytoin-5801 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| AIM1L | absent in melanoma 1-like |
| ARTN | artemin |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTG2 | BTG family, member 2 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEMP1 | cementum protein 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLDN17 | claudin 17 |
| CLEC11A | C-type lectin domain family 11, member A |
| CPNE7 | copine VII |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CXORF21 | chromosome X open reading frame 21 |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DUOX2 | dual oxidase 2 |
| DUSP2 | dual specificity phosphatase 2 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| FOXN3 | forkhead box N3 |
| FRMD4B | FERM domain containing 4B |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GFER | growth factor, augmenter of liver regeneration |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPR85 | G protein-coupled receptor 85 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGF1R | insulin-like growth factor 1 receptor |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| INHBE | inhibin, beta E |
| IRX5 | iroquois homeobox 5 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KERA | keratocan |
| KIAA1644 | KIAA1644 |
| KRTAP9-9 | keratin associated protein 9-9 |
| LBH | limb bud and heart development |
| LOX | lysyl oxidase |
| LTK | leukocyte receptor tyrosine kinase |
| MAP7D3 | MAP7 domain containing 3 |
| N4BP1 | NEDD4 binding protein 1 |
| NAV3 | neuron navigator 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 |
| NXPE4 | neurexophilin and PC-esterase domain family, member 4 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PHF3 | PHD finger protein 3 |
| PLCH1 | phospholipase C, eta 1 |
| PLCL2 | phospholipase C-like 2 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKCB | protein kinase C, beta |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB11B | RAB11B, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| RASAL2 | RAS protein activator like 2 |
| RPL35A | ribosomal protein L35a |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMAD6 | SMAD family member 6 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STK11 | serine/threonine kinase 11 |
| SYNGR3 | synaptogyrin 3 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMPRSS5 | transmembrane protease, serine 5 |
| TSKS | testis-specific serine kinase substrate |
| TUBB1 | tubulin, beta 1 class VI |
| TULP1 | tubby like protein 1 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VSNL1 | visinin-like 1 |
| WDR78 | WD repeat domain 78 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARL15 | ADP-ribosylation factor-like 15 |
| ART1 | ADP-ribosyltransferase 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AXIN1 | axin 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BEND5 | BEN domain containing 5 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CBX4 | chromobox homolog 4 |
| CCDC71 | coiled-coil domain containing 71 |
| CD82 | CD82 molecule |
| CEP295 | centrosomal protein 295kDa |
| CES3 | carboxylesterase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CSF1R | colony stimulating factor 1 receptor |
| DLL3 | delta-like 3 (Drosophila) |
| DNM1 | dynamin 1 |
| ECM1 | extracellular matrix protein 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FGL1 | fibrinogen-like 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FUZ | fuzzy planar cell polarity protein |
| GPR21 | G protein-coupled receptor 21 |
| GPR3 | G protein-coupled receptor 3 |
| HDAC7 | histone deacetylase 7 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H3C | histone cluster 1, H3c |
| HIST1H4E | histone cluster 1, H4e |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC4 | homeobox C4 |
| HOXC5 | homeobox C5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| INO80D | INO80 complex subunit D |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| ITK | IL2-inducible T-cell kinase |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYLIP | myosin regulatory light chain interacting protein |
| MYO1F | myosin IF |
| NABP1 | nucleic acid binding protein 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NINJ1 | ninjurin 1 |
| NOL12 | nucleolar protein 12 |
| NTF3 | neurotrophin 3 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PCDH17 | protocadherin 17 |
| PDE12 | phosphodiesterase 12 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLXNA3 | plexin A3 |
| PODXL2 | podocalyxin-like 2 |
| PRAMEF11 | PRAME family member 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS22 | protease, serine, 22 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SDC3 | syndecan 3 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SNPH | syntaphilin |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPRYD7 | SPRY domain containing 7 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMC7 | transmembrane channel-like 7 |
| TMEM132A | transmembrane protein 132A |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTC30A | tetratricopeptide repeat domain 30A |
| VASH1 | vasohibin 1 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF358 | zinc finger protein 358 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
