| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the mephenytoin-6158 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADAMTSL4 | ADAMTS-like 4 |
| ADORA1 | adenosine A1 receptor |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| APOD | apolipoprotein D |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CCDC33 | coiled-coil domain containing 33 |
| CCR8 | chemokine (C-C motif) receptor 8 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD6 | CD6 molecule |
| CDK10 | cyclin-dependent kinase 10 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEP135 | centrosomal protein 135kDa |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLEC10A | C-type lectin domain family 10, member A |
| CLTA | clathrin, light chain A |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CTSZ | cathepsin Z |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DSCAM | Down syndrome cell adhesion molecule |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EN1 | engrailed homeobox 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| EPN2 | epsin 2 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FERMT1 | fermitin family member 1 |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GAB1 | GRB2-associated binding protein 1 |
| GPC1 | glypican 1 |
| GPR137 | G protein-coupled receptor 137 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| ICOS | inducible T-cell co-stimulator |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| IL5RA | interleukin 5 receptor, alpha |
| INHBA | inhibin, beta A |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KLK8 | kallikrein-related peptidase 8 |
| LIMK1 | LIM domain kinase 1 |
| LRRC75B | leucine rich repeat containing 75B |
| MAGEA12 | melanoma antigen family A12 |
| MED25 | mediator complex subunit 25 |
| MLH3 | mutL homolog 3 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MTA1 | metastasis associated 1 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYRF | myelin regulatory factor |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PHOX2A | paired-like homeobox 2a |
| PNMA3 | paraneoplastic Ma antigen 3 |
| POSTN | periostin, osteoblast specific factor |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKCH | protein kinase C, eta |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RASL12 | RAS-like, family 12 |
| RCAN2 | regulator of calcineurin 2 |
| REC8 | REC8 meiotic recombination protein |
| RPS28 | ribosomal protein S28 |
| RUNDC3A | RUN domain containing 3A |
| RUNX1 | runt-related transcription factor 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SGPL1 | sphingosine-1-phosphate lyase 1 |
| SLC19A3 | solute carrier family 19 (thiamine transporter), member 3 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRPK3 | SRSF protein kinase 3 |
| TAAR3 | trace amine associated receptor 3 (gene/pseudogene) |
| TACC2 | transforming, acidic coiled-coil containing protein 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TLR5 | toll-like receptor 5 |
| TM2D1 | TM2 domain containing 1 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNXB | tenascin XB |
| TRAT1 | T cell receptor associated transmembrane adaptor 1 |
| TRD | T cell receptor delta locus |
| TSPAN4 | tetraspanin 4 |
| TTC38 | tetratricopeptide repeat domain 38 |
| WDR1 | WD repeat domain 1 |
| WWC1 | WW and C2 domain containing 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AKTIP | AKT interacting protein |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| AQP9 | aquaporin 9 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ARRB1 | arrestin, beta 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBX4 | chromobox homolog 4 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC9 | coiled-coil domain containing 9 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDHR2 | cadherin-related family member 2 |
| CELP | carboxyl ester lipase pseudogene |
| CHMP6 | charged multivesicular body protein 6 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLEC2D | C-type lectin domain family 2, member D |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTRL | chymotrypsin-like |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DUSP8 | dual specificity phosphatase 8 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| FAM127B | family with sequence similarity 127, member B |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GCH1 | GTP cyclohydrolase 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR21 | G protein-coupled receptor 21 |
| GPX2 | glutathione peroxidase 2 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4D | histone cluster 1, H4d |
| HP | haptoglobin |
| IFI44L | interferon-induced protein 44-like |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LOC730101 | uncharacterized LOC730101 |
| MAGEH1 | melanoma antigen family H1 |
| MAK | male germ cell-associated kinase |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NARFL | nuclear prelamin A recognition factor-like |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGP | phosphoglycolate phosphatase |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLP1 | proteolipid protein 1 |
| PLS1 | plastin 1 |
| PNOC | prepronociceptin |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RFPL3 | ret finger protein-like 3 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RWDD2A | RWD domain containing 2A |
| SCAI | suppressor of cancer cell invasion |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SHPK | sedoheptulokinase |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SPATA1 | spermatogenesis associated 1 |
| SPATA2L | spermatogenesis associated 2-like |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TEX15 | testis expressed 15 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM140 | transmembrane protein 140 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRAIP | TRAF interacting protein |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUFT1 | tuftelin 1 |
| USB1 | U6 snRNA biogenesis 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZIC3 | Zic family member 3 |
| ZNF354A | zinc finger protein 354A |
| ZNF428 | zinc finger protein 428 |
| ZNF695 | zinc finger protein 695 |
| ZNF701 | zinc finger protein 701 |
