| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the mephenytoin-6275 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AHI1 | Abelson helper integration site 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALS2CL | ALS2 C-terminal like |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APC | adenomatous polyposis coli |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA9 | carbonic anhydrase IX |
| CALD1 | caldesmon 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CFAP45 | cilia and flagella associated protein 45 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHKB | choline kinase beta |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 |
| CORT | cortistatin |
| CPA4 | carboxypeptidase A4 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DRD2 | dopamine receptor D2 |
| EDNRB | endothelin receptor type B |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ETV7 | ets variant 7 |
| FAM134B | family with sequence similarity 134, member B |
| FAM155A | family with sequence similarity 155, member A |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAS7 | growth arrest-specific 7 |
| GPR182 | G protein-coupled receptor 182 |
| HIC2 | hypermethylated in cancer 2 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HMGA1 | high mobility group AT-hook 1 |
| IPO8 | importin 8 |
| ITGA10 | integrin, alpha 10 |
| JAK2 | Janus kinase 2 |
| KLF2 | Kruppel-like factor 2 |
| LMF2 | lipase maturation factor 2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAP4 | microtubule-associated protein 4 |
| MID1 | midline 1 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MYOF | myoferlin |
| NAAA | N-acylethanolamine acid amidase |
| NCOA2 | nuclear receptor coactivator 2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PACRG | PARK2 co-regulated |
| PCLO | piccolo presynaptic cytomatrix protein |
| PCNX | pecanex homolog (Drosophila) |
| PLAGL2 | pleiomorphic adenoma gene-like 2 |
| PLK4 | polo-like kinase 4 |
| PLXNA1 | plexin A1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRKCI | protein kinase C, iota |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| QKI | QKI, KH domain containing, RNA binding |
| RBBP9 | retinoblastoma binding protein 9 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RIN2 | Ras and Rab interactor 2 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SDC2 | syndecan 2 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SIRPA | signal-regulatory protein alpha |
| SLC12A8 | solute carrier family 12, member 8 |
| SMAD3 | SMAD family member 3 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STK38L | serine/threonine kinase 38 like |
| SUGP1 | SURP and G patch domain containing 1 |
| SUGP2 | SURP and G patch domain containing 2 |
| TAOK2 | TAO kinase 2 |
| TAS2R13 | taste receptor, type 2, member 13 |
| TAZ | tafazzin |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UTRN | utrophin |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF277 | zinc finger protein 277 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF749 | zinc finger protein 749 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ANKRD40 | ankyrin repeat domain 40 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| CENPJ | centromere protein J |
| CEP72 | centrosomal protein 72kDa |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLDN15 | claudin 15 |
| CLDND1 | claudin domain containing 1 |
| CLSPN | claspin |
| COL9A2 | collagen, type IX, alpha 2 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNM1 | dynamin 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EMD | emerin |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM184A | family with sequence similarity 184, member A |
| FLCN | folliculin |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLCE | glucuronic acid epimerase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| IFT81 | intraflagellar transport 81 |
| IL17RA | interleukin 17 receptor A |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MICALL2 | MICAL-like 2 |
| MITF | microphthalmia-associated transcription factor |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MSX1 | msh homeobox 1 |
| MXRA7 | matrix-remodelling associated 7 |
| NEK11 | NIMA-related kinase 11 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PEX10 | peroxisomal biogenesis factor 10 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G15 | phospholipase A2, group XV |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU2F1 | POU class 2 homeobox 1 |
| PQLC1 | PQ loop repeat containing 1 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCPEP1 | serine carboxypeptidase 1 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SSFA2 | sperm specific antigen 2 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYCP2 | synaptonemal complex protein 2 |
| TCTN2 | tectonic family member 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRIM25 | tripartite motif containing 25 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| ULBP2 | UL16 binding protein 2 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF180 | zinc finger protein 180 |
| ZNF219 | zinc finger protein 219 |
| ZNF250 | zinc finger protein 250 |
| ZNF552 | zinc finger protein 552 |
| ZNF668 | zinc finger protein 668 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF770 | zinc finger protein 770 |
| ZNF787 | zinc finger protein 787 |
| ZNF816 | zinc finger protein 816 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |