meprylcaine-3544 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the meprylcaine-3544 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF2 AF4/FMR2 family, member 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX12 arachidonate 12-lipoxygenase
AMACR alpha-methylacyl-CoA racemase
AMT aminomethyltransferase
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ARC activity-regulated cytoskeleton-associated protein
BAAT bile acid CoA:amino acid N-acyltransferase
BAIAP2 BAI1-associated protein 2
BMP10 bone morphogenetic protein 10
BRD7P3 bromodomain containing 7 pseudogene 3
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BTN3A1 butyrophilin, subfamily 3, member A1
C11ORF1 chromosome 11 open reading frame 1
C7ORF69 chromosome 7 open reading frame 69
CA1 carbonic anhydrase I
CAV2 caveolin 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC57 coiled-coil domain containing 57
CELA3B chymotrypsin-like elastase family, member 3B
CFAP74 cilia and flagella associated protein 74
CHAD chondroadherin
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLIC2 chloride intracellular channel 2
CLPS colipase, pancreatic
CLSTN2 calsyntenin 2
CNGB1 cyclic nucleotide gated channel beta 1
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CST1 cystatin SN
DFNB31 deafness, autosomal recessive 31
DISC1 disrupted in schizophrenia 1
EFCAB6 EF-hand calcium binding domain 6
EFNB3 ephrin-B3
EPHX2 epoxide hydrolase 2, cytoplasmic
ERBB4 erb-b2 receptor tyrosine kinase 4
FGF5 fibroblast growth factor 5
GALK1 galactokinase 1
GCM2 glial cells missing homolog 2 (Drosophila)
GRIP2 glutamate receptor interacting protein 2
GRM3 glutamate receptor, metabotropic 3
GSPT1 G1 to S phase transition 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOMER3 homer scaffolding protein 3
HOXA1 homeobox A1
IGFBP5 insulin-like growth factor binding protein 5
INHBA inhibin, beta A
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
LAMC2 laminin, gamma 2
LHX2 LIM homeobox 2
LINC00472 long intergenic non-protein coding RNA 472
LOC399491
LPAR4 lysophosphatidic acid receptor 4
LTBP4 latent transforming growth factor beta binding protein 4
LUZP4 leucine zipper protein 4
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MIR622 microRNA 622
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOF myoferlin
MZF1 myeloid zinc finger 1
NEUROD1 neuronal differentiation 1
NLE1 notchless homolog 1 (Drosophila)
NOV nephroblastoma overexpressed
OCA2 oculocutaneous albinism II
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
PEAK1 pseudopodium-enriched atypical kinase 1
PLCG1 phospholipase C, gamma 1
PLXNC1 plexin C1
PPARD peroxisome proliferator-activated receptor delta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RBM5 RNA binding motif protein 5
RND1 Rho family GTPase 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SP100 SP100 nuclear antigen
SPAG6 sperm associated antigen 6
SRCAP Snf2-related CREBBP activator protein
SSX1 synovial sarcoma, X breakpoint 1
STAT2 signal transducer and activator of transcription 2, 113kDa
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TBXA2R thromboxane A2 receptor
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TLDC1 TBC/LysM-associated domain containing 1
TUBA4B tubulin, alpha 4b
UBE3A ubiquitin protein ligase E3A
VTCN1 V-set domain containing T cell activation inhibitor 1
WSCD1 WSC domain containing 1
ZBTB7A zinc finger and BTB domain containing 7A
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF280A zinc finger protein 280A
ZNF415 zinc finger protein 415
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTL8 actin-like 8
ADAM15 ADAM metallopeptidase domain 15
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
C5ORF45 chromosome 5 open reading frame 45
CCDC186 coiled-coil domain containing 186
CCDC88C coiled-coil domain containing 88C
CCNK cyclin K
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPC centromere protein C
CENPJ centromere protein J
CGA glycoprotein hormones, alpha polypeptide
CHRM3 cholinergic receptor, muscarinic 3
CNGB3 cyclic nucleotide gated channel beta 3
COG4 component of oligomeric golgi complex 4
CYBA cytochrome b-245, alpha polypeptide
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNMBP dynamin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FKBPL FK506 binding protein like
FLCN folliculin
GCHFR GTP cyclohydrolase I feedback regulator
GINS4 GINS complex subunit 4 (Sld5 homolog)
GOLM1 golgi membrane protein 1
GPATCH2L G patch domain containing 2-like
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
HEATR3 HEAT repeat containing 3
HIRA histone cell cycle regulator
HIST1H2BC histone cluster 1, H2bc
INCENP inner centromere protein antigens 135/155kDa
IRF9 interferon regulatory factor 9
ITPKB inositol-trisphosphate 3-kinase B
KCTD20 potassium channel tetramerization domain containing 20
KIFC1 kinesin family member C1
KLHL25 kelch-like family member 25
LAMB3 laminin, beta 3
LIN7A lin-7 homolog A (C. elegans)
LRP5 low density lipoprotein receptor-related protein 5
LRRC37A2 leucine rich repeat containing 37, member A2
MAP9 microtubule-associated protein 9
MEFV Mediterranean fever
METTL21B methyltransferase like 21B
MITF microphthalmia-associated transcription factor
MOCS3 molybdenum cofactor synthesis 3
MT1H metallothionein 1H
MTG1 mitochondrial ribosome-associated GTPase 1
MYL5 myosin, light chain 5, regulatory
NKAIN1 Na+/K+ transporting ATPase interacting 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGFRL1 opioid growth factor receptor-like 1
PCNXL4 pecanex-like 4 (Drosophila)
PGPEP1 pyroglutamyl-peptidase I
PHC2 polyhomeotic homolog 2 (Drosophila)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASAL1 RAS protein activator like 1 (GAP1 like)
RIN2 Ras and Rab interactor 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RUNDC3B RUN domain containing 3B
S100A4 S100 calcium binding protein A4
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC41A3 solute carrier family 41, member 3
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STIM1 stromal interaction molecule 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TDRD1 tudor domain containing 1
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TMEM62 transmembrane protein 62
TRAF2 TNF receptor-associated factor 2
TTC33 tetratricopeptide repeat domain 33
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP18 ubiquitin specific peptidase 18
VAX2 ventral anterior homeobox 2
WDR18 WD repeat domain 18
ZNF212 zinc finger protein 212
ZNF652 zinc finger protein 652
ZSCAN26 zinc finger and SCAN domain containing 26
ZSCAN31 zinc finger and SCAN domain containing 31