| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the meprylcaine-5723 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AADAC | arylacetamide deacetylase |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| APC | adenomatous polyposis coli |
| ARSD | arylsulfatase D |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATG10 | autophagy related 10 |
| B9D1 | B9 protein domain 1 |
| BGN | biglycan |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CD4 | CD4 molecule |
| CD47 | CD47 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CLSTN3 | calsyntenin 3 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| EDA | ectodysplasin A |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EGR1 | early growth response 1 |
| EHD2 | EH-domain containing 2 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPX | eosinophil peroxidase |
| FAM65B | family with sequence similarity 65, member B |
| FLJ11292 | |
| FLOT1 | flotillin 1 |
| FRMD1 | FERM domain containing 1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GIPR | gastric inhibitory polypeptide receptor |
| GLRA3 | glycine receptor, alpha 3 |
| GPR157 | G protein-coupled receptor 157 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HFE | hemochromatosis |
| HOXA11 | homeobox A11 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IRS4 | insulin receptor substrate 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KRT34 | keratin 34, type I |
| KRT86 | keratin 86, type II |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LY9 | lymphocyte antigen 9 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYL9 | myosin, light chain 9, regulatory |
| NAA11 | N(alpha)-acetyltransferase 11, NatA catalytic subunit |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NF1 | neurofibromin 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PALM | paralemmin |
| PDPN | podoplanin |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLXNC1 | plexin C1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTAFR | platelet-activating factor receptor |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RASAL2 | RAS protein activator like 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIX2 | SIX homeobox 2 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPRR1B | small proline-rich protein 1B |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| TBCD | tubulin folding cofactor D |
| TBKBP1 | TBK1 binding protein 1 |
| TGFA | transforming growth factor, alpha |
| TMEM180 | transmembrane protein 180 |
| TMEM63A | transmembrane protein 63A |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TSHR | thyroid stimulating hormone receptor |
| TSPAN32 | tetraspanin 32 |
| TTC12 | tetratricopeptide repeat domain 12 |
| UST | uronyl-2-sulfotransferase |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF268 | zinc finger protein 268 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ALPK1 | alpha-kinase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BEX1 | brain expressed, X-linked 1 |
| BTC | betacellulin |
| C1RL | complement component 1, r subcomponent-like |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNJL | cyclin J-like |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDK6 | cyclin-dependent kinase 6 |
| CENPO | centromere protein O |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM102A | family with sequence similarity 102, member A |
| FBRS | fibrosin |
| FGF13 | fibroblast growth factor 13 |
| FGL1 | fibrinogen-like 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRAMD1C | GRAM domain containing 1C |
| GRAMD4 | GRAM domain containing 4 |
| GTF2I | general transcription factor IIi |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOOK1 | hook microtubule-tethering protein 1 |
| IFNA14 | interferon, alpha 14 |
| IL17RB | interleukin 17 receptor B |
| IREB2 | iron-responsive element binding protein 2 |
| LINS | lines homolog (Drosophila) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC729164 | hCG1732469 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAGEB2 | melanoma antigen family B2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC3A | mucin 3A, cell surface associated |
| MYLIP | myosin regulatory light chain interacting protein |
| NDP | Norrie disease (pseudoglioma) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NINJ1 | ninjurin 1 |
| NME5 | NME/NM23 family member 5 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PDE8B | phosphodiesterase 8B |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| POM121 | POM121 transmembrane nucleoporin |
| PRR14L | proline rich 14-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAI | suppressor of cancer cell invasion |
| SCAMP5 | secretory carrier membrane protein 5 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPRYD7 | SPRY domain containing 7 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STEAP4 | STEAP family member 4 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TOM1 | target of myb1 (chicken) |
| TRIM25 | tripartite motif containing 25 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TWISTNB | TWIST neighbor |
| ULBP2 | UL16 binding protein 2 |
| VGF | VGF nerve growth factor inducible |
| VN1R1 | vomeronasal 1 receptor 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| YY2 | YY2 transcription factor |
| ZNF197 | zinc finger protein 197 |
| ZNF230 | zinc finger protein 230 |
| ZNF34 | zinc finger protein 34 |
| ZNF552 | zinc finger protein 552 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
