meptazinol-2906 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the meptazinol-2906 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACVR1B activin A receptor, type IB
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AQP9 aquaporin 9
AREG amphiregulin
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AXIN1 axin 1
B9D1 B9 protein domain 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C7ORF43 chromosome 7 open reading frame 43
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD3D CD3d molecule, delta (CD3-TCR complex)
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCP1 CUB domain containing protein 1
CECR1 cat eye syndrome chromosome region, candidate 1
CEP250 centrosomal protein 250kDa
CFP complement factor properdin
CLIP2 CAP-GLY domain containing linker protein 2
COL7A1 collagen, type VII, alpha 1
CORO2B coronin, actin binding protein, 2B
CREB3L1 cAMP responsive element binding protein 3-like 1
CXCR3 chemokine (C-X-C motif) receptor 3
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DZIP3 DAZ interacting zinc finger protein 3
ELN elastin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPN2 epsin 2
FASLG Fas ligand (TNF superfamily, member 6)
FBXL18 F-box and leucine-rich repeat protein 18
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FDXR ferredoxin reductase
FN1 fibronectin 1
GLE1 GLE1 RNA export mediator
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPC3 glypican 3
GRK5 G protein-coupled receptor kinase 5
HNF1B HNF1 homeobox B
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL24 interleukin 24
INA internexin neuronal intermediate filament protein, alpha
IQSEC1 IQ motif and Sec7 domain 1
ITGB5 integrin, beta 5
ITPKA inositol-trisphosphate 3-kinase A
KAT8 K(lysine) acetyltransferase 8
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KIF1C kinesin family member 1C
KIFC3 kinesin family member C3
KLHL36 kelch-like family member 36
LECT1 leukocyte cell derived chemotaxin 1
LTBP3 latent transforming growth factor beta binding protein 3
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MST1 macrophage stimulating 1
MTCL1 microtubule crosslinking factor 1
MUC1 mucin 1, cell surface associated
MYOZ3 myozenin 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGFR opioid growth factor receptor
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEX11A peroxisomal biogenesis factor 11 alpha
PLCD1 phospholipase C, delta 1
PLSCR3 phospholipid scramblase 3
PML promyelocytic leukemia
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTCRA pre T-cell antigen receptor alpha
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB6B RAB6B, member RAS oncogene family
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RIBC2 RIB43A domain with coiled-coils 2
RUNX1 runt-related transcription factor 1
SETBP1 SET binding protein 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC12A8 solute carrier family 12, member 8
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLMO1 slowmo homolog 1 (Drosophila)
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TLDC1 TBC/LysM-associated domain containing 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRD T cell receptor delta locus
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
VNN2 vanin 2
WISP1 WNT1 inducible signaling pathway protein 1
YLPM1 YLP motif containing 1
ZNF154 zinc finger protein 154
ZNF574 zinc finger protein 574
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADGRA3 adhesion G protein-coupled receptor A3
AKTIP AKT interacting protein
AOAH acyloxyacyl hydrolase (neutrophil)
ARMC7 armadillo repeat containing 7
BPI bactericidal/permeability-increasing protein
C16ORF59 chromosome 16 open reading frame 59
C17ORF80 chromosome 17 open reading frame 80
CBX4 chromobox homolog 4
CCRL2 chemokine (C-C motif) receptor-like 2
CD48 CD48 molecule
CDC73 cell division cycle 73
CDR2 cerebellar degeneration-related protein 2, 62kDa
CTPS2 CTP synthase 2
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DGAT1 diacylglycerol O-acyltransferase 1
DGKG diacylglycerol kinase, gamma 90kDa
DNAL4 dynein, axonemal, light chain 4
ELAC1 elaC ribonuclease Z 1
EML4 echinoderm microtubule associated protein like 4
ENO3 enolase 3 (beta, muscle)
FAM50B family with sequence similarity 50, member B
FAM53B family with sequence similarity 53, member B
FKBP5 FK506 binding protein 5
FOSL1 FOS-like antigen 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FZD2 frizzled class receptor 2
GEMIN8 gem (nuclear organelle) associated protein 8
GFOD2 glucose-fructose oxidoreductase domain containing 2
GPR22 G protein-coupled receptor 22
HIRA histone cell cycle regulator
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA4L heat shock 70kDa protein 4-like
ICK intestinal cell (MAK-like) kinase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JADE3 jade family PHD finger 3
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
LIN7A lin-7 homolog A (C. elegans)
LNPEP leucyl/cystinyl aminopeptidase
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCPH1 microcephalin 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MON1B MON1 secretory trafficking family member B
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MX2 MX dynamin-like GTPase 2
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NFE2L3 nuclear factor, erythroid 2-like 3
NLK nemo-like kinase
NT5M 5',3'-nucleotidase, mitochondrial
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP12 poly (ADP-ribose) polymerase family, member 12
PARPBP PARP1 binding protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PFKM phosphofructokinase, muscle
PGPEP1 pyroglutamyl-peptidase I
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PITX2 paired-like homeodomain 2
PLA2G15 phospholipase A2, group XV
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PRR4 proline rich 4 (lacrimal)
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RABL6 RAB, member RAS oncogene family-like 6
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RNF25 ring finger protein 25
RPGR retinitis pigmentosa GTPase regulator
RSAD1 radical S-adenosyl methionine domain containing 1
SCAMP4 secretory carrier membrane protein 4
SGMS1 sphingomyelin synthase 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC16A4 solute carrier family 16, member 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAI1 snail family zinc finger 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STX1A syntaxin 1A (brain)
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYCP2 synaptonemal complex protein 2
TCTN2 tectonic family member 2
THAP10 THAP domain containing 10
THEM6 thioesterase superfamily member 6
TLR6 toll-like receptor 6
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPS1 trichorhinophalangeal syndrome I
TSSC4 tumor suppressing subtransferable candidate 4
ULBP2 UL16 binding protein 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF155 zinc finger protein 155
ZNF32 zinc finger protein 32
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675