meptazinol-4188 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the meptazinol-4188 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAM22 ADAM metallopeptidase domain 22
ADAM28 ADAM metallopeptidase domain 28
AFF2 AF4/FMR2 family, member 2
ALDOB aldolase B, fructose-bisphosphate
APOB apolipoprotein B
APOD apolipoprotein D
ART1 ADP-ribosyltransferase 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BMP7 bone morphogenetic protein 7
C11ORF1 chromosome 11 open reading frame 1
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CADM3 cell adhesion molecule 3
CCK cholecystokinin
CCKBR cholecystokinin B receptor
CD33 CD33 molecule
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CEL carboxyl ester lipase
CEP152 centrosomal protein 152kDa
CES3 carboxylesterase 3
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLCA2 chloride channel accessory 2
CMA1 chymase 1, mast cell
DCX doublecortin
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIAPH2-AS1 DIAPH2 antisense RNA 1
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DMP1 dentin matrix acidic phosphoprotein 1
DMRT1 doublesex and mab-3 related transcription factor 1
DNAI2 dynein, axonemal, intermediate chain 2
DSCAM Down syndrome cell adhesion molecule
EDA ectodysplasin A
EDN3 endothelin 3
EGR1 early growth response 1
ELN elastin
ERBB4 erb-b2 receptor tyrosine kinase 4
EYA3 EYA transcriptional coactivator and phosphatase 3
FABP1 fatty acid binding protein 1, liver
FAM149A family with sequence similarity 149, member A
FOXO4 forkhead box O4
GAB1 GRB2-associated binding protein 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GHRHR growth hormone releasing hormone receptor
GJA8 gap junction protein, alpha 8, 50kDa
GLRA2 glycine receptor, alpha 2
GPC3 glypican 3
HAMP hepcidin antimicrobial peptide
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
ICA1 islet cell autoantigen 1, 69kDa
IL12B interleukin 12B
IL26 interleukin 26
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KIAA1045 KIAA1045
KIF1C kinesin family member 1C
KIF21B kinesin family member 21B
LEP leptin
LMO3 LIM domain only 3 (rhombotin-like 2)
LRP1 low density lipoprotein receptor-related protein 1
LUM lumican
METTL7A methyltransferase like 7A
MMRN2 multimerin 2
MNDA myeloid cell nuclear differentiation antigen
MT1G metallothionein 1G
MTRF1L mitochondrial translational release factor 1-like
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NRG1 neuregulin 1
NUDC nudC nuclear distribution protein
PIP prolactin-induced protein
PKNOX2 PBX/knotted 1 homeobox 2
PLN phospholamban
PLVAP plasmalemma vesicle associated protein
PMP2 peripheral myelin protein 2
PRMT2IP PRMT2 interacting protein
PROM1 prominin 1
PTGDR2 prostaglandin D2 receptor 2
REG1A regenerating islet-derived 1 alpha
RPL35A ribosomal protein L35a
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SELE selectin E
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEZ6L seizure related 6 homolog (mouse)-like
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SORCS3 sortilin-related VPS10 domain containing receptor 3
SOX5 SRY (sex determining region Y)-box 5
SP100 SP100 nuclear antigen
SRSF7 serine/arginine-rich splicing factor 7
SSX3 synovial sarcoma, X breakpoint 3
SYT11 synaptotagmin XI
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TLN2 talin 2
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
ZNF674 zinc finger protein 674

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACE angiotensin I converting enzyme
AKR1C4 aldo-keto reductase family 1, member C4
APOC4 apolipoprotein C-IV
ARMC6 armadillo repeat containing 6
ARPIN actin-related protein 2/3 complex inhibitor
BAG4 BCL2-associated athanogene 4
BCAS3 breast carcinoma amplified sequence 3
BEND5 BEN domain containing 5
BGLAP bone gamma-carboxyglutamate (gla) protein
BTF3P11 basic transcription factor 3 pseudogene 11
C5ORF42 chromosome 5 open reading frame 42
CAMKMT calmodulin-lysine N-methyltransferase
CDK3 cyclin-dependent kinase 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CHEK2 checkpoint kinase 2
CLDN11 claudin 11
CLK3 CDC-like kinase 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORT cortistatin
CSRNP3 cysteine-serine-rich nuclear protein 3
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGF epidermal growth factor
EML4 echinoderm microtubule associated protein like 4
ERAP2 endoplasmic reticulum aminopeptidase 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FRS3 fibroblast growth factor receptor substrate 3
FZD8 frizzled class receptor 8
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GMPR guanosine monophosphate reductase
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HIRIP3 HIRA interacting protein 3
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HMHA1 histocompatibility (minor) HA-1
HOXA1 homeobox A1
HOXA6 homeobox A6
HSPA1L heat shock 70kDa protein 1-like
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI35 interferon-induced protein 35
INF2 inverted formin, FH2 and WH2 domain containing
KDM7A lysine (K)-specific demethylase 7A
KLHL28 kelch-like family member 28
KRT75 keratin 75, type II
KRT86 keratin 86, type II
LRRC61 leucine rich repeat containing 61
MAL mal, T-cell differentiation protein
MATN3 matrilin 3
METTL16 methyltransferase like 16
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
MYOZ3 myozenin 3
NBEAL2 neurobeachin-like 2
ONECUT2 one cut homeobox 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAX9 paired box 9
PECR peroxisomal trans-2-enoyl-CoA reductase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMT2 protein-O-mannosyltransferase 2
PROX1 prospero homeobox 1
PRR7 proline rich 7 (synaptic)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RHOBTB2 Rho-related BTB domain containing 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A4 S100 calcium binding protein A4
SETD1A SET domain containing 1A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPTBN2 spectrin, beta, non-erythrocytic 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTN1 tectonic family member 1
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM177 transmembrane protein 177
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TMEM8A transmembrane protein 8A
TRAPPC6A trafficking protein particle complex 6A
TSPAN1 tetraspanin 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF137P zinc finger protein 137, pseudogene
ZNF391 zinc finger protein 391