mepyramine-1568 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the mepyramine-1568 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACTC1 actin, alpha, cardiac muscle 1
ACVRL1 activin A receptor type II-like 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCY6 adenylate cyclase 6
AKAP8L A kinase (PRKA) anchor protein 8-like
ARHGAP33 Rho GTPase activating protein 33
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AXIN1 axin 1
BAX BCL2-associated X protein
BMP2K BMP2 inducible kinase
BMP7 bone morphogenetic protein 7
BMPR1A bone morphogenetic protein receptor, type IA
C8ORF44 chromosome 8 open reading frame 44
CD177 CD177 molecule
CDC42 cell division cycle 42
CEND1 cell cycle exit and neuronal differentiation 1
CIAO1 cytosolic iron-sulfur assembly component 1
CLIC4 chloride intracellular channel 4
CORO7 coronin 7
CTBP2 C-terminal binding protein 2
CUL5 cullin 5
DCAF8 DDB1 and CUL4 associated factor 8
DOK5 docking protein 5
DUSP2 dual specificity phosphatase 2
E2F1 E2F transcription factor 1
EHBP1 EH domain binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM57A family with sequence similarity 57, member A
FBXW4 F-box and WD repeat domain containing 4
FSCN1 fascin actin-bundling protein 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GIMAP5 GTPase, IMAP family member 5
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GSK3A glycogen synthase kinase 3 alpha
HEG1 heart development protein with EGF-like domains 1
HIRA histone cell cycle regulator
HSF1 heat shock transcription factor 1
HSPB11 heat shock protein family B (small), member 11
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIFC1 kinesin family member C1
KRIT1 KRIT1, ankyrin repeat containing
KTN1 kinectin 1 (kinesin receptor)
LINC00339 long intergenic non-protein coding RNA 339
LMAN2L lectin, mannose-binding 2-like
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRK1 leucine-rich repeat kinase 1
MAP2K3 mitogen-activated protein kinase kinase 3
MKL1 megakaryoblastic leukemia (translocation) 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO1C myosin IC
NDRG2 NDRG family member 2
NEK3 NIMA-related kinase 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLCG1 phospholipase C, gamma 1
PLS1 plastin 1
POGZ pogo transposable element with ZNF domain
POU5F1B POU class 5 homeobox 1B
PRKCA protein kinase C, alpha
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PRRC2B proline-rich coiled-coil 2B
PSIP1 PC4 and SFRS1 interacting protein 1
RAB22A RAB22A, member RAS oncogene family
RANBP3 RAN binding protein 3
RBBP5 retinoblastoma binding protein 5
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL23AP7 ribosomal protein L23a pseudogene 7
RPS11 ribosomal protein S11
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RWDD3 RWD domain containing 3
SAG S-antigen; retina and pineal gland (arrestin)
SDHAF3 succinate dehydrogenase complex assembly factor 3
SERINC5 serine incorporator 5
SIRT6 sirtuin 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35E1 solute carrier family 35, member E1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMC5 structural maintenance of chromosomes 5
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOAT1 sterol O-acyltransferase 1
SOD2 superoxide dismutase 2, mitochondrial
SPRY4 sprouty homolog 4 (Drosophila)
SRSF7 serine/arginine-rich splicing factor 7
SSBP2 single-stranded DNA binding protein 2
SUGP1 SURP and G patch domain containing 1
TDRD3 tudor domain containing 3
THUMPD1 THUMP domain containing 1
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TM2D1 TM2 domain containing 1
TMEM159 transmembrane protein 159
TSC22D2 TSC22 domain family, member 2
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZMYM1 zinc finger, MYM-type 1
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACOT9 acyl-CoA thioesterase 9
ADAT1 adenosine deaminase, tRNA-specific 1
AES amino-terminal enhancer of split
AKIRIN1 akirin 1
ALPK1 alpha-kinase 1
APOBR apolipoprotein B receptor
APOD apolipoprotein D
ATP13A1 ATPase type 13A1
BAHCC1 BAH domain and coiled-coil containing 1
BCL7B B-cell CLL/lymphoma 7B
BCL7C B-cell CLL/lymphoma 7C
C1GALT1C1 C1GALT1-specific chaperone 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAPG capping protein (actin filament), gelsolin-like
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD82 CD82 molecule
CDC34 cell division cycle 34
CEP85 centrosomal protein 85kDa
CHKB choline kinase beta
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COG7 component of oligomeric golgi complex 7
CPNE1 copine I
CRYM crystallin, mu
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DDIT3 DNA-damage-inducible transcript 3
DMBT1 deleted in malignant brain tumors 1
DPH2 DPH2 homolog (S. cerevisiae)
DRAM1 DNA-damage regulated autophagy modulator 1
ELMO1 engulfment and cell motility 1
FAM114A1 family with sequence similarity 114, member A1
FAM193B family with sequence similarity 193, member B
FAM63A family with sequence similarity 63, member A
FBXO31 F-box protein 31
FCHO1 FCH domain only 1
FPGS folylpolyglutamate synthase
GLOD4 glyoxalase domain containing 4
GPR137B G protein-coupled receptor 137B
GPR27 G protein-coupled receptor 27
GRPR gastrin-releasing peptide receptor
GSTA4 glutathione S-transferase alpha 4
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTF2IRD1 GTF2I repeat domain containing 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HNRNPF heterogeneous nuclear ribonucleoprotein F
HRAS Harvey rat sarcoma viral oncogene homolog
IFITM3 interferon induced transmembrane protein 3
IL4R interleukin 4 receptor
LMBR1L limb development membrane protein 1-like
LOC642236 FSHD region gene 1 pseudogene
LSP1 lymphocyte-specific protein 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MIS18BP1 MIS18 binding protein 1
MON1B MON1 secretory trafficking family member B
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCTP phosphatidylcholine transfer protein
PEF1 penta-EF-hand domain containing 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PNPLA6 patatin-like phospholipase domain containing 6
PRMT5 protein arginine methyltransferase 5
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PTGES2 prostaglandin E synthase 2
PUS1 pseudouridylate synthase 1
RAB1B RAB1B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB4B RAB4B, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RHBDD3 rhomboid domain containing 3
RHOC ras homolog family member C
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAMP5 secretory carrier membrane protein 5
SCML1 sex comb on midleg-like 1 (Drosophila)
SETD1B SET domain containing 1B
SH2D2A SH2 domain containing 2A
SIPA1 signal-induced proliferation-associated 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SND1-IT1 SND1 intronic transcript 1
SPEF1 sperm flagellar 1
TESK2 testis-specific kinase 2
THAP4 THAP domain containing 4
TIAM2 T-cell lymphoma invasion and metastasis 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM242 transmembrane protein 242
TMEM62 transmembrane protein 62
TMPRSS6 transmembrane protease, serine 6
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TUBA4B tubulin, alpha 4b
WDR19 WD repeat domain 19
WDR46 WD repeat domain 46
WDR82 WD repeat domain 82
ZNF33B zinc finger protein 33B
ZNF529 zinc finger protein 529