mepyramine-3184 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mepyramine-3184 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM7 ADAM metallopeptidase domain 7
ADGRB3 adhesion G protein-coupled receptor B3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APAF1 apoptotic peptidase activating factor 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL3 ADP-ribosylation factor-like 3
ASPN asporin
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1QL1 complement component 1, q subcomponent-like 1
C21ORF2 chromosome 21 open reading frame 2
CA9 carbonic anhydrase IX
CAPN9 calpain 9
CCDC85B coiled-coil domain containing 85B
CCL2 chemokine (C-C motif) ligand 2
CDC14B cell division cycle 14B
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEMIP cell migration inducing protein, hyaluronan binding
CLEC7A C-type lectin domain family 7, member A
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRISP2 cysteine-rich secretory protein 2
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCHS2 dachsous cadherin-related 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIAPH2 diaphanous-related formin 2
DLG4 discs, large homolog 4 (Drosophila)
DOK5 docking protein 5
DRD2 dopamine receptor D2
ECE1 endothelin converting enzyme 1
FLJ11292
FN1 fibronectin 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GIF gastric intrinsic factor (vitamin B synthesis)
GPR21 G protein-coupled receptor 21
GPX5 glutathione peroxidase 5
GYPB glycophorin B (MNS blood group)
HAP1 huntingtin-associated protein 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HCG4 HLA complex group 4 (non-protein coding)
HFE hemochromatosis
ICOSLG inducible T-cell co-stimulator ligand
IL18 interleukin 18
IL2RA interleukin 2 receptor, alpha
ITGA7 integrin, alpha 7
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KLK2 kallikrein-related peptidase 2
KRT19P2 keratin 19 pseudogene 2
LECT2 leukocyte cell-derived chemotaxin 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMD1 LIM domains containing 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MFGE8 milk fat globule-EGF factor 8 protein
MGAM maltase-glucoamylase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP19 matrix metallopeptidase 19
MTAP methylthioadenosine phosphorylase
MUC2 mucin 2, oligomeric mucus/gel-forming
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOF myoferlin
MYT1L myelin transcription factor 1-like
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
PARP8 poly (ADP-ribose) polymerase family, member 8
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFC platelet derived growth factor C
PER2 period circadian clock 2
PHF1 PHD finger protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP5C protein phosphatase 5, catalytic subunit
PRB1 proline-rich protein BstNI subfamily 1
PRELP proline/arginine-rich end leucine-rich repeat protein
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RDH16 retinol dehydrogenase 16 (all-trans)
SCG2 secretogranin II
SIGLEC9 sialic acid binding Ig-like lectin 9
SIPA1 signal-induced proliferation-associated 1
SLC16A4 solute carrier family 16, member 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SOGA1 suppressor of glucose, autophagy associated 1
SORT1 sortilin 1
SPRED2 sprouty-related, EVH1 domain containing 2
TCP10L t-complex 10-like
TGM2 transglutaminase 2
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TNNI3K TNNI3 interacting kinase
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4
UGT8 UDP glycosyltransferase 8
VPREB3 pre-B lymphocyte 3
ZNF155 zinc finger protein 155
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
AFAP1 actin filament associated protein 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB2 arrestin, beta 2
ASAP1-IT1 ASAP1 intronic transcript 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAG4 BCL2-associated athanogene 4
C11ORF80 chromosome 11 open reading frame 80
CAPRIN2 caprin family member 2
CCDC132 coiled-coil domain containing 132
CCDC69 coiled-coil domain containing 69
CGREF1 cell growth regulator with EF-hand domain 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHPF chondroitin polymerizing factor
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
COG4 component of oligomeric golgi complex 4
DENND4A DENN/MADD domain containing 4A
DMTN dematin actin binding protein
DNA2 DNA replication helicase/nuclease 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC6L excision repair cross-complementation group 6-like
FAM189A2 family with sequence similarity 189, member A2
FGGY FGGY carbohydrate kinase domain containing
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXN2 forkhead box N2
FRS2 fibroblast growth factor receptor substrate 2
GMPR guanosine monophosphate reductase
GPR19 G protein-coupled receptor 19
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC5 homeobox C5
HOXC8 homeobox C8
HPS6 Hermansky-Pudlak syndrome 6
IDI2-AS1 IDI2 antisense RNA 1
IL15RA interleukin 15 receptor, alpha
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD20 potassium channel tetramerization domain containing 20
KDM8 lysine (K)-specific demethylase 8
KIAA0586 KIAA0586
KLF2 Kruppel-like factor 2
LAMB3 laminin, beta 3
LDHB lactate dehydrogenase B
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC257152 uncharacterized LOC257152
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC14 leucine rich repeat containing 14
LYZ lysozyme
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED9 mediator complex subunit 9
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUC3A mucin 3A, cell surface associated
MYL5 myosin, light chain 5, regulatory
MYO1F myosin IF
NRSN2 neurensin 2
NT5E 5'-nucleotidase, ecto (CD73)
NXPH4 neurexophilin 4
OLFML3 olfactomedin-like 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PADI2 peptidyl arginine deiminase, type II
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLL polymerase (DNA directed), lambda
PSKH1 protein serine kinase H1
PYCRL pyrroline-5-carboxylate reductase-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB3A RAB3A, member RAS oncogene family
RNF121 ring finger protein 121
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D4A SH2 domain containing 4A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRD5A3 steroid 5 alpha-reductase 3
STX1A syntaxin 1A (brain)
TMEM120B transmembrane protein 120B
TOM1 target of myb1 (chicken)
TPST1 tyrosylprotein sulfotransferase 1
TTC23 tetratricopeptide repeat domain 23
TTC33 tetratricopeptide repeat domain 33
UBXN6 UBX domain protein 6
VAV1 vav 1 guanine nucleotide exchange factor
ZNF205 zinc finger protein 205
ZNF329 zinc finger protein 329
ZNF767P zinc finger family member 767, pseudogene
ZNF778 zinc finger protein 778
ZNF816 zinc finger protein 816
ZSCAN26 zinc finger and SCAN domain containing 26