| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the mepyramine-5869 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADCK2 | aarF domain containing kinase 2 |
| AIM2 | absent in melanoma 2 |
| APOM | apolipoprotein M |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| CA11 | carbonic anhydrase XI |
| CCDC85B | coiled-coil domain containing 85B |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CD22 | CD22 molecule |
| CDC42 | cell division cycle 42 |
| CES3 | carboxylesterase 3 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| COL11A2 | collagen, type XI, alpha 2 |
| CSNK1E | casein kinase 1, epsilon |
| CTSS | cathepsin S |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DST | dystonin |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GSTA3 | glutathione S-transferase alpha 3 |
| H1F0 | H1 histone family, member 0 |
| HBS1L | HBS1-like translational GTPase |
| HCFC1 | host cell factor C1 |
| HDAC5 | histone deacetylase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IL6 | interleukin 6 |
| IL7R | interleukin 7 receptor |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAMB4 | laminin, beta 4 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC61 | leucine rich repeat containing 61 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MECOM | MDS1 and EVI1 complex locus |
| MEFV | Mediterranean fever |
| MEGF9 | multiple EGF-like-domains 9 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MUC1 | mucin 1, cell surface associated |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEB | nebulin |
| NEK11 | NIMA-related kinase 11 |
| NOTCH4 | notch 4 |
| NRP2 | neuropilin 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PASK | PAS domain containing serine/threonine kinase |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PMP2 | peripheral myelin protein 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRM2 | protamine 2 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAB29 | RAB29, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS14 | regulator of G-protein signaling 14 |
| RHOT2 | ras homolog family member T2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPS14 | ribosomal protein S14 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RTN2 | reticulon 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STK16 | serine/threonine kinase 16 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TEX15 | testis expressed 15 |
| TGFB2 | transforming growth factor, beta 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM53 | transmembrane protein 53 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| UBOX5 | U-box domain containing 5 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WEE1 | WEE1 G2 checkpoint kinase |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AEN | apoptosis enhancing nuclease |
| AMT | aminomethyltransferase |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARMC7 | armadillo repeat containing 7 |
| ASF1B | anti-silencing function 1B histone chaperone |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CDCA3 | cell division cycle associated 3 |
| CDK3 | cyclin-dependent kinase 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CTSD | cathepsin D |
| CTSK | cathepsin K |
| CYTH2 | cytohesin 2 |
| DENND1B | DENN/MADD domain containing 1B |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| ECM1 | extracellular matrix protein 1 |
| EFNA4 | ephrin-A4 |
| EVPL | envoplakin |
| FADS2 | fatty acid desaturase 2 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FBRS | fibrosin |
| FGF13 | fibroblast growth factor 13 |
| FHOD1 | formin homology 2 domain containing 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR3 | G protein-coupled receptor 3 |
| HIRA | histone cell cycle regulator |
| HIST1H3G | histone cluster 1, H3g |
| HLX | H2.0-like homeobox |
| HYI | hydroxypyruvate isomerase (putative) |
| IFNA14 | interferon, alpha 14 |
| IFT22 | intraflagellar transport 22 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IREB2 | iron-responsive element binding protein 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0754 | KIAA0754 |
| KIAA0895 | KIAA0895 |
| KLHL3 | kelch-like family member 3 |
| LOC730101 | uncharacterized LOC730101 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MVP | major vault protein |
| NDE1 | nudE neurodevelopment protein 1 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NOTCH1 | notch 1 |
| NUBP2 | nucleotide binding protein 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| NUPL2 | nucleoporin like 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PARPBP | PARP1 binding protein |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PLSCR4 | phospholipid scramblase 4 |
| POM121 | POM121 transmembrane nucleoporin |
| POR | P450 (cytochrome) oxidoreductase |
| RNF122 | ring finger protein 122 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SALL2 | spalt-like transcription factor 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC35G2 | solute carrier family 35, member G2 |
| SNX16 | sorting nexin 16 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPAG4 | sperm associated antigen 4 |
| SPATA7 | spermatogenesis associated 7 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SYNPO | synaptopodin |
| TAGLN3 | transgelin 3 |
| TBC1D19 | TBC1 domain family, member 19 |
| THOP1 | thimet oligopeptidase 1 |
| TMEM183A | transmembrane protein 183A |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TOR4A | torsin family 4, member A |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM21 | tripartite motif containing 21 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP18 | ubiquitin specific peptidase 18 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF430 | zinc finger protein 430 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
