mepyramine-7223 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mepyramine-7223 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ALK anaplastic lymphoma receptor tyrosine kinase
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARSD arylsulfatase D
ATF7IP activating transcription factor 7 interacting protein
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BIRC3 baculoviral IAP repeat containing 3
BMP2K BMP2 inducible kinase
C14ORF79 chromosome 14 open reading frame 79
CALD1 caldesmon 1
CAPRIN2 caprin family member 2
CCHCR1 coiled-coil alpha-helical rod protein 1
CD3D CD3d molecule, delta (CD3-TCR complex)
CLCN7 chloride channel, voltage-sensitive 7
CPD carboxypeptidase D
CPED1 cadherin-like and PC-esterase domain containing 1
CRELD1 cysteine-rich with EGF-like domains 1
CRYAB crystallin, alpha B
CRYM crystallin, mu
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
DGKQ diacylglycerol kinase, theta 110kDa
DIO2 deiodinase, iodothyronine, type II
DMPK dystrophia myotonica-protein kinase
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM189A2 family with sequence similarity 189, member A2
FAM214B family with sequence similarity 214, member B
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGB fibrinogen beta chain
FGF12 fibroblast growth factor 12
FGL1 fibrinogen-like 1
FLJ11292
FSCN3 fascin actin-bundling protein 3, testicular
GPC1 glypican 1
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR3 G protein-coupled receptor 3
HBS1L HBS1-like translational GTPase
HDAC7 histone deacetylase 7
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HSF1 heat shock transcription factor 1
HSPA1L heat shock 70kDa protein 1-like
ICAM1 intercellular adhesion molecule 1
IDUA iduronidase, alpha-L-
IGFBP5 insulin-like growth factor binding protein 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL12RB1 interleukin 12 receptor, beta 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIAA0355 KIAA0355
KRT19P2 keratin 19 pseudogene 2
LCMT2 leucine carboxyl methyltransferase 2
LIMCH1 LIM and calponin homology domains 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MRPL41 mitochondrial ribosomal protein L41
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NPTXR neuronal pentraxin receptor
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OMD osteomodulin
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM3 PDZ and LIM domain 3
PHF20 PHD finger protein 20
PKD2L2 polycystic kidney disease 2-like 2
PLAU plasminogen activator, urokinase
PLK4 polo-like kinase 4
PSG1 pregnancy specific beta-1-glycoprotein 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RANBP3 RAN binding protein 3
RPAP1 RNA polymerase II associated protein 1
RREB1 ras responsive element binding protein 1
RS1 retinoschisin 1
RUNDC3A RUN domain containing 3A
SCN11A sodium channel, voltage gated, type XI alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIX2 SIX homeobox 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A16 solute carrier family 6, member 16
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPN sialophorin
SRCAP Snf2-related CREBBP activator protein
SSBP3 single stranded DNA binding protein 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT12 synaptotagmin XII
TAT tyrosine aminotransferase
TDRKH tudor and KH domain containing
TMOD1 tropomodulin 1
TMPRSS4 transmembrane protease, serine 4
TRIM3 tripartite motif containing 3
TRIP11 thyroid hormone receptor interactor 11
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF451 zinc finger protein 451
ZNF710 zinc finger protein 710
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTN4 actinin, alpha 4
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGAP10 Rho GTPase activating protein 10
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASB9 ankyrin repeat and SOCS box containing 9
ATAD5 ATPase family, AAA domain containing 5
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BEX4 brain expressed, X-linked 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
C10ORF88 chromosome 10 open reading frame 88
C1ORF109 chromosome 1 open reading frame 109
C21ORF91 chromosome 21 open reading frame 91
CDKL3 cyclin-dependent kinase-like 3
CHPF chondroitin polymerizing factor
CLDN15 claudin 15
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CORO2A coronin, actin binding protein, 2A
DCAF17 DDB1 and CUL4 associated factor 17
DENND4A DENN/MADD domain containing 4A
DSCAM Down syndrome cell adhesion molecule
F3 coagulation factor III (thromboplastin, tissue factor)
FAM169A family with sequence similarity 169, member A
FAM86C1 family with sequence similarity 86, member C1
FZD2 frizzled class receptor 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GJA1 gap junction protein, alpha 1, 43kDa
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IP6K1 inositol hexakisphosphate kinase 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0753 KIAA0753
KREMEN2 kringle containing transmembrane protein 2
LHX6 LIM homeobox 6
LMNB1 lamin B1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP5L low density lipoprotein receptor-related protein 5-like
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAST3 microtubule associated serine/threonine kinase 3
MFSD11 major facilitator superfamily domain containing 11
MFSD12 major facilitator superfamily domain containing 12
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MORC3 MORC family CW-type zinc finger 3
MRPL52 mitochondrial ribosomal protein L52
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
MYO1E myosin IE
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NECAB3 N-terminal EF-hand calcium binding protein 3
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PILRB paired immunoglobin-like type 2 receptor beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPP6R3 protein phosphatase 6, regulatory subunit 3
PROCR protein C receptor, endothelial
R3HCC1L R3H domain and coiled-coil containing 1-like
RNASEH2B ribonuclease H2, subunit B
SETD8 SET domain containing (lysine methyltransferase) 8
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPINK4 serine peptidase inhibitor, Kazal type 4
STBD1 starch binding domain 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNJ2BP synaptojanin 2 binding protein
TEP1 telomerase-associated protein 1
THBS3 thrombospondin 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TUBA3D tubulin, alpha 3d
TUBG2 tubulin, gamma 2
TWSG1 twisted gastrulation BMP signaling modulator 1
UBXN6 UBX domain protein 6
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
WDR18 WD repeat domain 18
WDR60 WD repeat domain 60
ZFP69B ZFP69 zinc finger protein B
ZNF141 zinc finger protein 141
ZNF16 zinc finger protein 16
ZNF430 zinc finger protein 430
ZNF443 zinc finger protein 443
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668