| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the merbromin-2577 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| APP | amyloid beta (A4) precursor protein |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP9B | ATPase, class II, type 9B |
| BEST1 | bestrophin 1 |
| BIN1 | bridging integrator 1 |
| BMP7 | bone morphogenetic protein 7 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| BTG2 | BTG family, member 2 |
| CAPN9 | calpain 9 |
| CDO1 | cysteine dioxygenase type 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CSNK1E | casein kinase 1, epsilon |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EMP1 | epithelial membrane protein 1 |
| FBXO22 | F-box protein 22 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FRMD8 | FERM domain containing 8 |
| FUS | FUS RNA binding protein |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GALC | galactosylceramidase |
| GK3P | glycerol kinase 3 pseudogene |
| GPR21 | G protein-coupled receptor 21 |
| GPR22 | G protein-coupled receptor 22 |
| GPX2 | glutathione peroxidase 2 |
| GSN | gelsolin |
| GTF2I | general transcription factor IIi |
| GTPBP1 | GTP binding protein 1 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL27RA | interleukin 27 receptor, alpha |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MCL1 | myeloid cell leukemia 1 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MCOLN1 | mucolipin 1 |
| MKL2 | MKL/myocardin-like 2 |
| MRC2 | mannose receptor, C type 2 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTAP | methylthioadenosine phosphorylase |
| NCKAP1L | NCK-associated protein 1-like |
| NF2 | neurofibromin 2 (merlin) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIP | prolactin-induced protein |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRR5 | proline rich 5 (renal) |
| RAB35 | RAB35, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RHOH | ras homolog family member H |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RRP1B | ribosomal RNA processing 1B |
| RUNX1 | runt-related transcription factor 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMAD5 | SMAD family member 5 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPP1 | secreted phosphoprotein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TLN2 | talin 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIM23 | tripartite motif containing 23 |
| TRIM25 | tripartite motif containing 25 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TYRO3 | TYRO3 protein tyrosine kinase |
| USP53 | ubiquitin specific peptidase 53 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF215 | zinc finger protein 215 |
| ZNF280B | zinc finger protein 280B |
| Symbol | Name |
|---|---|
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APOC4 | apolipoprotein C-IV |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BTNL3 | butyrophilin-like 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CABP2 | calcium binding protein 2 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCDC176 | coiled-coil domain containing 176 |
| CDHR2 | cadherin-related family member 2 |
| CELP | carboxyl ester lipase pseudogene |
| CFAP45 | cilia and flagella associated protein 45 |
| CHPF | chondroitin polymerizing factor |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRYGC | crystallin, gamma C |
| CTC1 | CTS telomere maintenance complex component 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DPYS | dihydropyrimidinase |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EPN1 | epsin 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM163A | family with sequence similarity 163, member A |
| FAM222B | family with sequence similarity 222, member B |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXD2 | forkhead box D2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GIPR | gastric inhibitory polypeptide receptor |
| GPR68 | G protein-coupled receptor 68 |
| GRPR | gastrin-releasing peptide receptor |
| GSN-AS1 | GSN antisense RNA 1 |
| HIST1H3G | histone cluster 1, H3g |
| HOXB9 | homeobox B9 |
| ICK | intestinal cell (MAK-like) kinase |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNA17 | interferon, alpha 17 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA10 | integrin, alpha 10 |
| JAM3 | junctional adhesion molecule 3 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC100287590 | uncharacterized LOC100287590 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MGP | matrix Gla protein |
| MTMR12 | myotubularin related protein 12 |
| MYH15 | myosin, heavy chain 15 |
| MYO1E | myosin IE |
| MYOZ3 | myozenin 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NRAP | nebulin-related anchoring protein |
| NSUN6 | NOP2/Sun domain family, member 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDH12 | protocadherin 12 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PMEL | premelanosome protein |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PRDM12 | PR domain containing 12 |
| PRO2964 | uncharacterized protein PRO2964 |
| PRR7 | proline rich 7 (synaptic) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPEF1 | sperm flagellar 1 |
| STMN4 | stathmin-like 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSC22D4 | TSC22 domain family, member 4 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZNF219 | zinc finger protein 219 |
