merbromin-3439 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the merbromin-3439 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADM adrenomedullin
AKAP7 A kinase (PRKA) anchor protein 7
AOX1 aldehyde oxidase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOM apolipoprotein M
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP1 Rho GTPase activating protein 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARTN artemin
BTBD7 BTB (POZ) domain containing 7
CCDC28B coiled-coil domain containing 28B
CCNO cyclin O
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CLIC4 chloride intracellular channel 4
COMT catechol-O-methyltransferase
DIEXF digestive organ expansion factor homolog (zebrafish)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
E2F4 E2F transcription factor 4, p107/p130-binding
ECE1 endothelin converting enzyme 1
FAM214B family with sequence similarity 214, member B
FCMR Fc fragment of IgM receptor
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FKBP5 FK506 binding protein 5
FKBP8 FK506 binding protein 8, 38kDa
FLOT1 flotillin 1
GALC galactosylceramidase
GALK1 galactokinase 1
GPATCH3 G patch domain containing 3
GPER1 G protein-coupled estrogen receptor 1
GPR143 G protein-coupled receptor 143
GREB1 growth regulation by estrogen in breast cancer 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFT27 intraflagellar transport 27
ITGB4 integrin, beta 4
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM4A lysine (K)-specific demethylase 4A
KIAA1109 KIAA1109
KLHL22 kelch-like family member 22
LHX1 LIM homeobox 1
LMNA lamin A/C
LPCAT4 lysophosphatidylcholine acyltransferase 4
LUZP1 leucine zipper protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MARK2 MAP/microtubule affinity-regulating kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED14 mediator complex subunit 14
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MORC3 MORC family CW-type zinc finger 3
MYO1E myosin IE
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NT5E 5'-nucleotidase, ecto (CD73)
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITX1 paired-like homeodomain 1
PLEC plectin
POLL polymerase (DNA directed), lambda
PRLR prolactin receptor
PSD4 pleckstrin and Sec7 domain containing 4
R3HDM4 R3H domain containing 4
RAB11B RAB11B, member RAS oncogene family
RBM8A RNA binding motif protein 8A
RGS3 regulator of G-protein signaling 3
RHEB Ras homolog enriched in brain
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
S100A13 S100 calcium binding protein A13
S100A9 S100 calcium binding protein A9
SCD5 stearoyl-CoA desaturase 5
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC35E2 solute carrier family 35, member E2
SMTN smoothelin
SOX15 SRY (sex determining region Y)-box 15
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTBN1 spectrin, beta, non-erythrocytic 1
ST20 suppressor of tumorigenicity 20
ST5 suppression of tumorigenicity 5
TADA2A transcriptional adaptor 2A
TBX19 T-box 19
THBS3 thrombospondin 3
TMPO thymopoietin
TMPRSS4 transmembrane protease, serine 4
TRAFD1 TRAF-type zinc finger domain containing 1
TRAPPC10 trafficking protein particle complex 10
TTC33 tetratricopeptide repeat domain 33
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB6 zinc finger and BTB domain containing 6
ZNF235 zinc finger protein 235
ZNF253 zinc finger protein 253

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATAD5 ATPase family, AAA domain containing 5
BCL2L2 BCL2-like 2
BEX4 brain expressed, X-linked 4
BTBD2 BTB (POZ) domain containing 2
C2ORF27A chromosome 2 open reading frame 27A
C5AR2 complement component 5a receptor 2
C5ORF45 chromosome 5 open reading frame 45
CAPN5 calpain 5
CCP110 centriolar coiled coil protein 110kDa
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DEAF1 DEAF1 transcription factor
DNAL4 dynein, axonemal, light chain 4
DUSP13 dual specificity phosphatase 13
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELOVL4 ELOVL fatty acid elongase 4
ENO2 enolase 2 (gamma, neuronal)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
EXO5 exonuclease 5
FBXL2 F-box and leucine-rich repeat protein 2
FBXW12 F-box and WD repeat domain containing 12
FGF23 fibroblast growth factor 23
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H2BC histone cluster 1, H2bc
HMOX1 heme oxygenase 1
HSPA1L heat shock 70kDa protein 1-like
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
JADE1 jade family PHD finger 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
KIAA0125 KIAA0125
KIF13B kinesin family member 13B
LHX6 LIM homeobox 6
LOC390998 ribosomal protein L10 pseudogene
LYPLA2P1 lysophospholipase II pseudogene 1
MED9 mediator complex subunit 9
MGC12488
MRPL44 mitochondrial ribosomal protein L44
NUP62CL nucleoporin 62kDa C-terminal like
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G3 phospholipase A2, group III
PLD3 phospholipase D family, member 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PNKP polynucleotide kinase 3'-phosphatase
QSER1 glutamine and serine rich 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF2 ring finger protein 2
SAYSD1 SAYSVFN motif domain containing 1
SCAMP5 secretory carrier membrane protein 5
SLC12A8 solute carrier family 12, member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STARD5 StAR-related lipid transfer (START) domain containing 5
STRA6 stimulated by retinoic acid 6
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TMSB15A thymosin beta 15a
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSPAN15 tetraspanin 15
TSPYL2 TSPY-like 2
USP27X ubiquitin specific peptidase 27, X-linked
VAX2 ventral anterior homeobox 2
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB22 zinc finger and BTB domain containing 22
ZC3H3 zinc finger CCCH-type containing 3
ZNF141 zinc finger protein 141
ZNF204P zinc finger protein 204, pseudogene
ZNF350 zinc finger protein 350
ZNF442 zinc finger protein 442
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747