mercaptopurine-334 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mercaptopurine-334 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
AKR1C3 aldo-keto reductase family 1, member C3
ATG13 autophagy related 13
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BCL6 B-cell CLL/lymphoma 6
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BTG2 BTG family, member 2
C17ORF59 chromosome 17 open reading frame 59
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CD70 CD70 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CIITA class II, major histocompatibility complex, transactivator
CLCN5 chloride channel, voltage-sensitive 5
COL5A1 collagen, type V, alpha 1
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DDIT4 DNA-damage-inducible transcript 4
DRD2 dopamine receptor D2
DSE dermatan sulfate epimerase
DVL3 dishevelled segment polarity protein 3
DXO decapping exoribonuclease
EFR3B EFR3 homolog B (S. cerevisiae)
ENG endoglin
EPHB1 EPH receptor B1
FAM89B family with sequence similarity 89, member B
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
FRMPD1 FERM and PDZ domain containing 1
GADD45B growth arrest and DNA-damage-inducible, beta
GLG1 golgi glycoprotein 1
GPR35 G protein-coupled receptor 35
GPR87 G protein-coupled receptor 87
GPSM3 G-protein signaling modulator 3
GSK3A glycogen synthase kinase 3 alpha
GULP1 GULP, engulfment adaptor PTB domain containing 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HSPB3 heat shock 27kDa protein 3
IFFO1 intermediate filament family orphan 1
IFITM1 interferon induced transmembrane protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHL1 kelch-like family member 1
LMTK1 lemur tail kinase 1
LTK leukocyte receptor tyrosine kinase
MED28 mediator complex subunit 28
MMP8 matrix metallopeptidase 8
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
N4BP2L2 NEDD4 binding protein 2-like 2
NDRG2 NDRG family member 2
NFX1 nuclear transcription factor, X-box binding 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PQLC2 PQ loop repeat containing 2
PRF1 perforin 1 (pore forming protein)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRD protein tyrosine phosphatase, receptor type, D
RRBP1 ribosome binding protein 1
RTN2 reticulon 2
RWDD2A RWD domain containing 2A
SERHL2 serine hydrolase-like 2
SETD4 SET domain containing 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SMAD3 SMAD family member 3
SPEG SPEG complex locus
SQSTM1 sequestosome 1
SRCAP Snf2-related CREBBP activator protein
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TEX13B testis expressed 13B
TGM2 transglutaminase 2
TGM3 transglutaminase 3
TTR transthyretin
UBE4B ubiquitination factor E4B
WBP4 WW domain binding protein 4
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR48 WD repeat domain 48
WIZ widely interspaced zinc finger motifs
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF277 zinc finger protein 277
ZNF33B zinc finger protein 33B
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALX1 ALX homeobox 1
ANKRD11 ankyrin repeat domain 11
ARGLU1 arginine and glutamate rich 1
ARMC7 armadillo repeat containing 7
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C10ORF88 chromosome 10 open reading frame 88
C1ORF159 chromosome 1 open reading frame 159
C5ORF28 chromosome 5 open reading frame 28
CAMKV CaM kinase-like vesicle-associated
CARD8 caspase recruitment domain family, member 8
CCDC177 coiled-coil domain containing 177
CCDC94 coiled-coil domain containing 94
CCNK cyclin K
CD5 CD5 molecule
CD83 CD83 molecule
CDCA8 cell division cycle associated 8
CETN1 centrin, EF-hand protein, 1
CHGB chromogranin B
CLCN6 chloride channel, voltage-sensitive 6
COPZ2 coatomer protein complex, subunit zeta 2
CORO1A coronin, actin binding protein, 1A
CROT carnitine O-octanoyltransferase
CTRB2 chymotrypsinogen B2
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DISC1 disrupted in schizophrenia 1
EGR3 early growth response 3
EHD3 EH-domain containing 3
ERO1L ERO1-like (S. cerevisiae)
FAM110D family with sequence similarity 110, member D
FANCF Fanconi anemia, complementation group F
FJX1 four jointed box 1 (Drosophila)
FLRT1 fibronectin leucine rich transmembrane protein 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAB2 GRB2-associated binding protein 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GATAD2A GATA zinc finger domain containing 2A
GDF2 growth differentiation factor 2
GMEB1 glucocorticoid modulatory element binding protein 1
GMIP GEM interacting protein
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRIA4 glutamate receptor, ionotropic, AMPA 4
GSN-AS1 GSN antisense RNA 1
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
H2AFJ H2A histone family, member J
HBD hemoglobin, delta
HIST1H1D histone cluster 1, H1d
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IL19 interleukin 19
IP6K1 inositol hexakisphosphate kinase 1
IRX4 iroquois homeobox 4
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KREMEN2 kringle containing transmembrane protein 2
LIAS lipoic acid synthetase
LINC00652 long intergenic non-protein coding RNA 652
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MALL mal, T-cell differentiation protein-like
MC3R melanocortin 3 receptor
MEPE matrix extracellular phosphoglycoprotein
MMRN2 multimerin 2
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NNAT neuronatin
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARG poly (ADP-ribose) glycohydrolase
PCSK7 proprotein convertase subtilisin/kexin type 7
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
PYCRL pyrroline-5-carboxylate reductase-like
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAP1A RAP1A, member of RAS oncogene family
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOH ras homolog family member H
RORC RAR-related orphan receptor C
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAG S-antigen; retina and pineal gland (arrestin)
SDCCAG3 serologically defined colon cancer antigen 3
SEC14L5 SEC14-like 5 (S. cerevisiae)
SIDT1 SID1 transmembrane family, member 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SNORA21 small nucleolar RNA, H/ACA box 21
STAB2 stabilin 2
TMEM176A transmembrane protein 176A
TMPRSS5 transmembrane protease, serine 5
TULP1 tubby like protein 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR43 WD repeat domain 43
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF512B zinc finger protein 512B
ZXDC ZXD family zinc finger C