| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the mercaptopurine-667 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ADH6 | alcohol dehydrogenase 6 (class V) |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| ATF6 | activating transcription factor 6 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BIN1 | bridging integrator 1 |
| BLK | BLK proto-oncogene, Src family tyrosine kinase |
| BLMH | bleomycin hydrolase |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD8A | CD8a molecule |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLDN1 | claudin 1 |
| CNTN1 | contactin 1 |
| CRYM | crystallin, mu |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| DEDD | death effector domain containing |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DISC1 | disrupted in schizophrenia 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| ECE2 | endothelin converting enzyme 2 |
| FN1 | fibronectin 1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GAB1 | GRB2-associated binding protein 1 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GLRX3 | glutaredoxin 3 |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GPR107 | G protein-coupled receptor 107 |
| H2AFY2 | H2A histone family, member Y2 |
| HOXD9 | homeobox D9 |
| HRH1 | histamine receptor H1 |
| INO80B | INO80 complex subunit B |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KHK | ketohexokinase (fructokinase) |
| KIAA1045 | KIAA1045 |
| KLHL1 | kelch-like family member 1 |
| KYNU | kynureninase |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LRRN2 | leucine rich repeat neuronal 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED1 | mediator complex subunit 1 |
| MT1G | metallothionein 1G |
| MYL10 | myosin, light chain 10, regulatory |
| MYL12B | myosin, light chain 12B, regulatory |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYLIP | myosin regulatory light chain interacting protein |
| NCS1 | neuronal calcium sensor 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUP214 | nucleoporin 214kDa |
| PASK | PAS domain containing serine/threonine kinase |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 |
| PKP1 | plakophilin 1 |
| PLIN2 | perilipin 2 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTH1R | parathyroid hormone 1 receptor |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB29 | RAB29, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| REC8 | REC8 meiotic recombination protein |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RGS3 | regulator of G-protein signaling 3 |
| RNF141 | ring finger protein 141 |
| RUNDC3A | RUN domain containing 3A |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPRR1A | small proline-rich protein 1A |
| SYNGR1 | synaptogyrin 1 |
| TAGLN3 | transgelin 3 |
| TBC1D2B | TBC1 domain family, member 2B |
| TLE3 | transducin-like enhancer of split 3 |
| TMEM97 | transmembrane protein 97 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TP63 | tumor protein p63 |
| TRIB2 | tribbles pseudokinase 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TWIST1 | twist family bHLH transcription factor 1 |
| WDR61 | WD repeat domain 61 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| WWC2 | WW and C2 domain containing 2 |
| ZNF778 | zinc finger protein 778 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ADRB2 | adrenoceptor beta 2, surface |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARMC7 | armadillo repeat containing 7 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| ATXN2 | ataxin 2 |
| AXIN1 | axin 1 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNA1 | cyclin A1 |
| CCS | copper chaperone for superoxide dismutase |
| CDH18 | cadherin 18, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CPOX | coproporphyrinogen oxidase |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERF | Ets2 repressor factor |
| EXOSC9 | exosome component 9 |
| FUZ | fuzzy planar cell polarity protein |
| GALK1 | galactokinase 1 |
| GDF9 | growth differentiation factor 9 |
| GPR21 | G protein-coupled receptor 21 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HIST1H4J | histone cluster 1, H4j |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLX | H2.0-like homeobox |
| HMGA2 | high mobility group AT-hook 2 |
| HMHA1 | histocompatibility (minor) HA-1 |
| IL22 | interleukin 22 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRS1 | insulin receptor substrate 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIF18A | kinesin family member 18A |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LIPG | lipase, endothelial |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MED23 | mediator complex subunit 23 |
| MOB3B | MOB kinase activator 3B |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NUPL2 | nucleoporin like 2 |
| NVL | nuclear VCP-like |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PLAU | plasminogen activator, urokinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POLM | polymerase (DNA directed), mu |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTX3 | pentraxin 3, long |
| RAD54L | RAD54-like (S. cerevisiae) |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RSPH6A | radial spoke head 6 homolog A (Chlamydomonas) |
| SIX1 | SIX homeobox 1 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMO | smoothened, frizzled class receptor |
| SNAI2 | snail family zinc finger 2 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| TBX3 | T-box 3 |
| THBS4 | thrombospondin 4 |
| TJP2 | tight junction protein 2 |
| TMEM8A | transmembrane protein 8A |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSPAN5 | tetraspanin 5 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR41 | WD repeat domain 41 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF432 | zinc finger protein 432 |
| ZNF671 | zinc finger protein 671 |
| ZNF696 | zinc finger protein 696 |
| ZNF787 | zinc finger protein 787 |
